Adjusted prevalence of severe fatigue with 95% CI before and after Delta and Omicron SARS-CoV-2 infections and in matched uninfected participants Infected and uninfected participants were matched on month and year of pre-infection CIS-fatigue assessment, the pre-infection CIS-fatigue score, age group (18–59 years, 60–85 years), sex (male, female), medical risk condition (yes, no), and vaccination status (unvaccinated, primary vaccinated, booster vaccinated). CIS = Checklist Individual Strength; CI = Confidence Interval.

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Adjusted mean post- vs pre-infection CIS-fatigue scores with 95% CI...

Adjusted prevalence of severe fatigue with 95% CI over time since first...

Adjusted prevalence of severe fatigue with 95% CI before and after...

Prospective cohort study of fatigue before and after SARS-CoV-2 infection in the Netherlands

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Full-text available

Mar 2025

Fatigue is one of the most common persistent symptoms of SARS-CoV-2 infection. We aimed to assess fatigue during and after a SARS-CoV-2 infection by age, sex, presence of a medical risk condition, SARS-CoV-2 variant and vaccination status, accounting for pre-infection fatigue and compared with uninfected individuals. We used data from an ongoing pr...