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Absorption of a UV-C photon by DNA and formation of a thymine dimer 

Absorption of a UV-C photon by DNA and formation of a thymine dimer 

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Background: Despite the great health significance of Legionella, there is only little information on their UV sensitivity. Besides Legionella pneumophila only L. longbeachae has been investigated so far. Methods: In this study L. rubrilucens has been spread on buffered charcoal yeast extract agar and irradiated with the 254 nm UV-C emission of a me...

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... radiation is usually generated by mercury vapor lamps, which show strong emission at a wavelength of 254 nm. The UV-C radiation is absorbed by DNA, resulting in the formation of thymine dimers [6] as illustrated in Figure 1. This DNA damage hinders gene expression and DNA replication and should lead to the death of the irradiated microorganisms. ...

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Article
Full-text available
Background: Despite the great health significance of Legionella, there is only little information on their UV sensitivity. Besides Legionella pneumophila only L. longbeachae has been investigated so far. Methods: In this study L. rubrilucens has been spread on buffered charcoal yeast extract agar and irradiated with the 254 nm UV-C emission of a me...