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Abb. 2 Schematische Darstellung der striatalen Nebensysteme und deren kortikale Projektionen: Der rote Pfeil kennzeichnet die Efferenz vom vmPFC, der dunkelorange vom OFC, der hellorange vom ACC und der gelbe Pfeil kennzeichnet die Efferenzen vom dPFC; die braunen Pfeile beschreiben die relevanten Verbindungen des Belohnungssystems. Abkürzungen: Amy, Amygdala-Komplex; dACC, dorsaler anteriorer Cingulärer Kortex; dPFC, dorsaler präfrontaler Kortex; Hipp, Hippocampus; LHb, laterale Habenula ; Hypo, Hypothalamus; OFC, orbitaler frontaler Kortex; PPT, Pedunculopontiner Nucleus; S, shell, SNc, substantia nigra, pars compacta; STN, subthalamischer Nucleus.; VP, ventrales Pallidum; VTA, ventrale tegmentale Area; vmPFC, ventraler medialer präfrontaler Kortex. (Übernommen aus: Haber SN, Rauch SL. Neurocircuitry: a window into the networks underlying neuropsychiatric disease. Neuropsychopharmacol 2010; 35: 1 – 3).  

Abb. 2 Schematische Darstellung der striatalen Nebensysteme und deren kortikale Projektionen: Der rote Pfeil kennzeichnet die Efferenz vom vmPFC, der dunkelorange vom OFC, der hellorange vom ACC und der gelbe Pfeil kennzeichnet die Efferenzen vom dPFC; die braunen Pfeile beschreiben die relevanten Verbindungen des Belohnungssystems. Abkürzungen: Amy, Amygdala-Komplex; dACC, dorsaler anteriorer Cingulärer Kortex; dPFC, dorsaler präfrontaler Kortex; Hipp, Hippocampus; LHb, laterale Habenula ; Hypo, Hypothalamus; OFC, orbitaler frontaler Kortex; PPT, Pedunculopontiner Nucleus; S, shell, SNc, substantia nigra, pars compacta; STN, subthalamischer Nucleus.; VP, ventrales Pallidum; VTA, ventrale tegmentale Area; vmPFC, ventraler medialer präfrontaler Kortex. (Übernommen aus: Haber SN, Rauch SL. Neurocircuitry: a window into the networks underlying neuropsychiatric disease. Neuropsychopharmacol 2010; 35: 1 – 3).  

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The interaction of basal ganglia and other brain regions is more complex regarding anatomic and functional perspectives than previously assumed. Hence, the classical basal ganglia model has to be extended to at least four satellite systems modulating motor-executive, associative and limbic-motivational brain regions: (i) an indirect projection syst...

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