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... two drugs resulted in downregulation (2-ΔΔCT value <1) of lasR gene occurred in all tested strains where quercetin had better effect than meloxicam. Regarding their effect on rhlR expression quercetin caused downregulation in all tested samples while meloxicam caused downregulation in PAO1 and P1 and it surprisingly caused upregulation in the clinical isolate, as shown in Figure 2 and Table 3. ...