ISSUE TITLE: Enantioselective Synthesis in Organic, Materials and Medicinal Chemistry GUEST-EDITORS: (1) Prof. E. Lete, Email: esther.lete@ehu.es (2) Prof. N. Sotomayor, Email: nuria.sotomayor@ehu.es (3) Assoc. Prof. S. Arrasate, Email: sonia.arrasate@ehu.es, LinkedIn: http://linkd.in/WeZ6kv AFFILIATION: Department of Organic Chemistry II, Faculty of Science and Technology, University of The Basque Country UPV/EHU, Leioa, 48940, Bizkaia, Basque Country, Spain. RGate: https://www.researchgate.net/institution/Universidad_del_Pais_Vasco_Euskal_Herriko_Unibertsitatea Co-EDITOR-In-Chief: Research Prof. Humberto González-Díaz Email: humberto.gonzalezdiaz@ehu.es RGate: https://www.researchgate.net/profile/H_Gonzalez-Diaz/ Linkedin: http://es.linkedin.com/pub/humberto-gonzalez-diaz/22/422/b77 (1) Department of Organic Chemistry II, Faculty of Science and Technology, University of The Basque Country UPV/EHU, Leioa, 48940, Bizkaia, Basque Country, Spain. (2) Ikerbasque, Basque Foundation for Science, 48011, Bilbao, Bizkaia, Basque Country, Spain. FB page: https://www.facebook.com/Ikerbasque

It is important to start from a structure with 5 carbon atoms !!

Lis, Neubeck(2006) Smoke-free hospitals

Once answered what is "passive" and what "active" in electronics, https://www.researchgate.net/post/What_is_passive_and_what_active_in_electricity_and_electronics_Can_we_make_passive_elements_become_less_passive_neutral_or_even_active? we should answer what is "linear" and what - "nonlinear"... and even to see if there are some relations between these four fundamental categories. Some "genius" speculations-:) are already proposed by Gregg and Lutz in the question above. Actually, the main question here is, "What is a nonlinear resistor?" My deep inner conviction is that only to show the nonlinear IV curve is not enough to answer this question; we have to show how this odd curve is obtained. I have been thinking about this problem since the late 80's when I began marveling at the weird negative resistance phenomenon. Thus I have finally created my own "philosophy" about the nonlinear phenomenon. But I have not yet got a satisfactory confirmation of my speculations from some "scientific luminary" just because famous persons, blinded by fame, do not have time to answer (or are confused by) such unsolicited questions... My notion of a "linear resistor" (the simplest case) is that this is an element with steady, constant, static, invariable (toward the input quantity variations) resistance; i.e., "linear" means "static" for me. When we change the input quantity (e.g., the voltage across the resistor), the operating point draws the real IV curve of this humble element (ohmic resistor) - a line beginning from the coordinates origin and graphically representing the Ohm's law: http://www.circuit-fantasia.com/my-students/ske2004/classes/class1/v-to-i-old-page6-3.html This linear resistor can be a "variable linear resistor" (a rheostat) with the reservation that we will not change its resistance together with the input quantity changes. Its IV curve remains a line beginning from the origin but it only changes its slope according to the instant linear resistance. But if, at some moment and for some reasons, we break our promise to keep the resistance steady while the input quantity wiggles, the operating point changes its trajectory. Now it begins drawing a new imaginary, artificial, virtual, "nonlinear" IV curve with some new (vertical, horizontal, negative, whatever...) slope. So, my notion of a "nonlinear resistor" is that this is an element with a kind of "self-variable" (toward the input quantity variations) resistance; i.e., "nonlinear" means "dynamic" for me. To show graphically this "dynamization", I superimpose two IV curves (lines) on the same coordinate system: the first - of the instant ohmic resistance; the second - of the input source. In contrast to the linear graphical representation, where only the input source IV curve moves, here both the curves simultaneously move and, as a result, the operating point draws the new nonlinear IV curve. I have developed this idea to the utmost in the Wikibooks story about the negative differential resistance: http://en.wikibooks.org/wiki/Circuit_Idea/Negative_Differential_Resistance My questions are: Is it reasonable to present the nonlinear resistor as a dynamic linear resistor? Can we illustrate its operation in this way?