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  • Dr. Muhammad Zubair Asghar added an answer in Scientific Publication:
    How do you increase the visibility of published article?

    I'm curious to learn about any additional PR steps you can take to increase the visibility of your published articles. Here are some steps I try to take (in various combinations, depending on the nature of the article):

    • Cite the paper whenever appropriate
    • Post preprint/postprint on arXiv/similar repository
    • Bring a pile of reprints to the next conference
    • Write a press release together with the press office of my university
    • Send announcements out on an appropriate email list
    • Put a paper copy in any academic lunch room I happen to visit

    What am I missing? What are your tricks and secrets?



    Dr. Muhammad Zubair Asghar

    Nice sharing dear Bahram Kazemian

  • Xingang Guan asked a question in Protein Elution:
    How can I get the recombinant protein without urea and salt?

    I had produced and purified the recombinant protein by genetic engineering. However, the protein was eluted from resin with high salt and urea solution. When I use dialysis method to remove them, the proteins aggregated.  When using ultrafiltration, the protein did not accumulate in upper solution. I just want the protein in low salt solutin but with high concentration.

  • W. M. Bernstein added an answer in Impulse Control Disorders:
    Are there any case reports of Modafinil causing imp use control disorders?
    Any case reports of Modafinil causing impulse control issues like gambling
    W. M. Bernstein

    I've never encountered it. And I prescribe it a lot.

    w.m. bernstein

  • Bruce E Oddson added an answer in k-means:
    K-medians vs k-medians - k-medians to ordinal data- do you agree with me?

    I've ordinal data - in my opinion I should use k-medians in spite of k-means do you agree with me?

    Thanks in advance.


    Bruce E Oddson

    I am sorry but the question as posed is not clear.

  • Pedram Abdollahi added an answer in Etching:
    LePera etchant - Why does in our case Picric acid crystallize on mixing with Sodium metabisulfite?

    We are trying to etch DP600 using LePera etchant. As soon as we add Sodium metabisulfite to Picral, the picric acid crystallizes as powder at the bottom. Even after stirring for long it does not goes back into solution. We etched despite all this and then picric acid crystallized on specimen surface. Can someone tell what we could be doing wrong? Thanks…

    Pedram Abdollahi

    The etchant is a mixture of two pristine solutions . Volumes of 30 ml of reagent 1

    and 30ml of reagent 2 are poured into two different beakers. "Just before the etching

    is started, the solutions are mixed in a small crystallizing vessel"

    + 1 more attachment

  • Quy Nguyen added an answer in Educational Games:
    What do you think about educational games developed in Virtual Worlds like OpenSimulator?

    Does this tool satisfactory can be used for this purpose?

    Quy Nguyen

    I think its good and necessary in education

  • Muhammad Khattab asked a question in Solvents:
    What does it mean when blank (solvent) has intense peak in excitation spectrum, but weak one in emission (<10%) of sample intensity?

    Also, sometimes i notice the reverse where weak excitation peak and strong emission peak. For the best of my knowledge, the solvent peak should be (<10%) of sample peak in both excitation and emission measurements.

  • Brian Prasad added an answer in Innovation Studies:
    Are there in developed countries models of cooperation between large and small firms?

    I am studying the models of cooperation and relationship between NTBFs or SMEs and large companies (supply chain, R&D or ….). I would appreciate if you could help me, Are there in developed countries program, plan or act about support of formation this relationships?

    Brian Prasad

    It requires a framework to entice cooperation between small and large firms. See the article discussed herein.

    • Source
      [Show abstract] [Hide abstract]
      ABSTRACT: This study proposes a conceptual framework for software systems that support concurrent engineering (CE). The framework uses a CE model inspired by the distributed artificial intelligence paradigm. We illustrate the framework using an example from the printed circuit board (PCB) product development process. This underlying application or problem domain is decomposed into several sub-domains that are relatively independent. Each sub-domain contains some specialized human or system knowledge, and is generally referred to as "agents." Each agent then uses its particular knowledge base and inference mechanism to contribute to the solution of the overall problem. The support for CE is achieved by considering all the agents as part of a ''virtual" team environment, i.e, a team of multiple experts working oollaboratively to solve the problem. We refer to this CE software-support framework as the Multi-Agent based Cooperative Expert System (MACES). The major elements of MACES include a multi-agent based architecture, a cooperative centered mode of interaction among agents, a dynamic constraint network based knowledge representation to represent the knowledge base of the agents, and a negotiation protocol based on a conflict resolution mechanism. CE94 Conference Proceedings of Concurrent Engineering: Research and Applications 1994 ISBN: 096424490X 9780964244900 OCLC Number: 36292580 Notes: "Sponsored by Concurrent Technologies Corporation, International Society for Productivity Enhancement, CERA journal." Description: ix, 574 p. : ill. ; 28 cm.
      Concurrent Engineering: Research & Applications - A Global Perspecive, CE94, Conference, Pittsburgh, Pennsylvania, USA, Publisher: Concurrent Technologies Corp. c1994 , Johnstown, PA; 08/1994
  • Mohamad Irwan Ahmad added an answer in Psychological Contract:
    Does anyone here familiar with Mechanical Turk (MTurk)?

    I need to use it in my data collection. My proposed samples are working employees since I would like to assess their psychological contract breach as a initial study. 

    Mohamad Irwan Ahmad

    Thanks Tim Straub and Jesse Chandler.

  • Acapman Azman asked a question in Photocatalysts:
    May someone help me. How to do calculation on sol gel if I need to produce 97% Cerium dioxide and 3% Copper dioxide?

    sol gel

    photocatalyst Ce-Cu

  • Mohamad Irwan Ahmad added an answer in Psychological Contract:
    Does anyone have the Psychological Contract Fulfilment scale at work?

    Does anyone have the Psychological Contract Fulfilment scale at work? I need it to measure organisation's promise, trust and fairness among employees at workplace.


    Mohamad Irwan Ahmad

    Thanks Zhou Jiang

  • Mehrdad Taheran asked a question in Electrospinning:
    Where to find affordable coaxial needles for electrospinning?

    Does anybody know where I can find affordable coaxial needles for electrospinning of PAN?

  • Clara Thao Hoang Tran asked a question in Surface Chemistry:
    How to prepare sample for analyzing surface chemistry of nanoparticles using ATR-FTIR?

    I found in literature that FTIR can be used to study the surface chemistry of nanoparticles. Can someone describe in detail how to prepare samples for this measurement?

    Thank you!

  • George Dishman added an answer in Stars:
    What conditions were required for Stellar formation pre inflation epoch (as w/ the Pearlman Spiral cosmological redshift hypothesis) ?

    Assume stars formed prior to the inflation epoch as hypothesized in the Pearlman Spiral cosmological redshift hypothesis for various reasons. The stars would have been much more condense (as the universe was moving from the initial singularity) prior to the universe expanding 13B light years +- during the inflation epoch.
    Under what conditions could stars have formed during that span prior to cosmic inflation?

    George Dishman

    RMP: I think i know where the misunderstanding is.

    I don't think there's any misunderstanding, we just hold different views.

    RMP: While what you say makes a lot of sense under the standard cosmology model (SCM), if that is the actuality. under the Pearlman spiral cosmological redshift (CR) hypothesis and cosmology model we can take the identical factual evidence and derive very different predictions, calculations and conclusions.

    Perhaps, but there is a vast array of other information available that you should research first.

    RMP: SCM - Gas expanded before stars formed.
    RMP: Pearlman Sprial - Stars already existed (in a much denser form) prior to the expansion.

    Expansion is ongoing but that is a separate issue. Stars give off ultra-violet light which ionises neutral gas into plasma. Neutral hydrogen absorbs a particular frequency called the Lyman-Alpha line but the ionised plasma does not so we can tell when the first stars formed by looking at that ionisation. As a result, we know it was much later than the formation of the gas.

    RMP: SCM - CMB of today must have been so hot to start that stars could not have survived. this is based on the assumption CR is due to an expanding universe over the past 13B +/-years would have diluted/dissipated the CMB temp.

    No, the CMB from which we get the light was only about 2970K, stars are much hotter. Even the Sun is 5870K and hot blue stars often exceed 20,000K. The absence of stars in the few tens of millions of years after the CMB was released is based on the observation that the gas became neutral hydrogen which would be impossible if there had been any stars then. For more information, look up the "Lyman Alpha Forest" and the "Peterson Trough". Any alternative cosmology you wish to try will have to explain those in detail.

    RMP: Pearlman Spiral (which is short for Pearlman SPIRALL ;) - The CR is due to RALL (Redshift Attests to Lagging Light) in SPIRALL

    I have no idea what that means. Many people have tried to explain how the frequency of light can be changed without expansion but all have failed, it is harder than you think. In particular, remember that any explanation must also explain why all frequencies of light are shifted by the same ratio for any given source, and sources of light which have well defined durations also last longer in exact proportion to the change of frequency.

    Then how do you explain the fact that it was so much denser and hotter that it glowed, something we see as the CMB now? Where did the helium and deuterium in the universe come from? The temperature needed to produce those exceeds 300 million degrees and it had to cool rapidly to avoid destroying the elements as fast as they formed

    RMP: so the universe is best estimated at 5776 years old

    Don't be silly, dendrochronology alone can date trees to exact years back nearly 14,000 years and of course there has been life on Earth for several billion years.

  • Getachew Agegnehu added an answer in Physiological Signals:
    What are the mechanistic insights about the response of a nutrient at various levels of plant organisation ?

    Nutrient response of a plant is expressed through a sequence of events , called physiological signals , the origin of which is claimed to differ from one plant to another plant species. Our most of the nutrient responses are expressed at whole plant level , especially on the basis of consumable plant parts . My question pertains to following set of sub-questions:

    * Why do we evaluate response of a nutrient at the whole plant level ?. Is it  because of ease of measurement ?.

    * Whether the response of a nutrient is visible at gene level?

    *  Whether response of a nutrient visible at cellular level ?. If so , whether  the signal is translated  at whole plant level ?

    * Do you feel  , expression of nutrient response is a sequel of significant communications from  sub-cellular level to whole plant level?

    * How do you see the role of plant species in these nutrient response-induced cellular functions?

    Hope , We will get better insights into the plant responses operating in response to nutrient application .   

    Getachew Agegnehu

    The way how Dr. Paul tried to relate the ancient Greek Philosophy with science is very interesting.

  • José Arzola-Ruiz added an answer in Genetic Algorithm:
    Building Blocks: Do you agree it is really a critical issue?

    Some works in the literature (Goldberg/Bridges, for instance) have demonstrated that standard Genetic Algorithms (GAs) usually cause the building blocks disruption of the solutions. On the other hand, some current papers have shown that the use of a GA special implementation may be a viable alternative in order to overcome this issue. In this sense, I would like to know what you think about that. Please, try answering my question in a short clear response if possible.

    Thank you very much in advance!

    José Arzola-Ruiz

    Dear Lauro Cássio:

    The building blocks problem depends on the nature of the concrete task you are solving. But there are a variety of algorithms that makes evolve solutions codes populations (one or more) helped by a diversity of operators, GA could be included in this variety. Some of these algorithms could be more effective for a diversity of tasks.

     The first article I wrotte devoted to this method "The Integration of Variables method". an additional information you can find in other works that you can download in my researchgate page, like Analysis and Synthesis of Engineering Systems.

    Excepting the GA, the rest of the algorithms included in the method doesn't present the building blocks problem.

    Best wishes,

    José Arzola

  • Giovanni Ltb asked a question in Bayesian:
    If we want inference to be driven solely form data, why do we even bother specifying a prior? What is the sense of a so called "uninformative prior"?

    What is the raison d'être of uninformative priors? Isn't one of the Bayesian goals that of allowing to systematically incorporate prior information into inference?


  • Will K Reeves added an answer in Lymnaea:
    When is the convenient time to look for an intermediate host freshwater snails, Lymnaea rubiginosa, at a grazing area?

    Recently, we when to the paddy field in early morning, about 6.30 am, to look for the freshwater snails. During observation, there were no Lymnaied snails was present there. Before this, studies have been done in that area, the liver fluke infection has occurred in cattle. But, still did not find the presence of snails that act as intermediate host for this disease.Therefore, we want to know when and where to find the snail intermediate host that causes liver fluke disease in cattle. Thanks. 

    Will K Reeves

    I find that with Lymnaied snails you can find them almost year round in many parts of the world.  If you really believe the infections are coming from the ponds on the field you should start to check around the edges of the water and perhaps on emergent vegetation.  Since Lymnaied snails are amphibious I often find them 5-10 cm or so out of the water sitting on a substrata like cement or plants.

  • V. P. N Nziko added an answer in Hydrogen Bonding:
    How do I calculate hydrogen bond energies?

    We investigate a dimer of an organic molecule. It is linked together by two hydrogen bridges.

            a) What is the best way to calculate the bonding energy of the dimer?

    One possible approach is to optimize the geometries of the dimer and the monomer with classical DFT methods, let’s say B3LYP/6-311+G(d,p). The energy of the monomer is corrected with BSSE correction. The difference between (2x)monomer and dimer energy gives the bond energy of the hydrogen bond.

           b) Is that correct?

           c) How to do this type of calculation with modern dispersion-corrected DFT methods?

           d) Which method / basis set combination would you propose?

    V. P. N Nziko

    Your ans to B is yes. as to which method is the best..I will say use MP2 methods with big basis sets.

  • Marc Tessera added an answer in Cognitive Systems:
    Is Chalmers' so-called "hard problem" in consciousness real?

    In his 2014 book "Consciousness and the Brain: Deciphering How the Brain Codes Our Thoughts" Stanislas Dehaene wrote "Chalmers, a philosopher of the University of Arizona, is famous for introducing a distinction between the easy and the hard problems. The easy problem of consciousness, he argues, consists in explaining the many functions of the brain: how do we recognize a face, a word, or a landscape? How do we extract information form the senses and use it to guide our behavior? How do we generate sentences to describe what we feel?

    “Although all these questions are associated with consciousness,” Chalmers argues, “they all concern the objective mechanisms of the cognitive system, and consequently, we have every reason to expect that continued work in cognitive psychology and neuroscience will answer them. By contrast the hard problem is the “question of how physical processes in the brain give rise to subjective experience … the way things feel for the subject. When we see for example, we experience visual sensations, such as that of vivid blue. Or think of the ineffable sound of a distant oboe, the agony of an intense pain, the sparkle of happiness or the meditative quality of a moment lost in thought … It is these phenomena that poses the real mystery of the mind”."

    Stanislas Dehaene's opinion is "that Chalmers swapped the labels: it is the “easy” problem that is hard, while the “hard” problem just seems hard because it engages ill-defined intuitions. Once our intuition is educated by cognitive neuroscience and computer simulations, Chalmers’ “hard problem” will evaporate".

    Personally, I agree with Stanislas Dehaene's opinion.

    Marc Tessera


    Even in the case of an illusion you need their self-reports to validate the fact that the involved individuals have a similar conscious experience.

  • Cuong Tran added an answer in Water Quality:
    Can carbonate/bicarbonate concentrations be calculated using major ions/TDS/pH/EC?

    I need to construct Piper diagrams using historical water quality data, but don't have carbonate/bicarbonate concentrations... Please advise if it's possible.

    Cuong Tran

    Hi Gerhard,

    The link below is one of the most accurate method to calculate what you want. Currently, I am using this method for working out alkalinity and other species in the samples.

    Good luck


  • Can Kiessling added an answer in Trizol:
    Any advice on RNA isolation of skin sample for rt-PCR?


    To extract RNA properly out of a whole Skin sample (mouse), how can I homogenize the sample? would the ceramic beads be enough for that? and later, which is better, TriFast or Trizol?

    Thanks alot in advance!

    Can Kiessling

    Why not pass them through 18 and 21-gauge needles?

    I have used this method with success for RNA isolation in mice ventricles which have become rubberised (difficult to break down) as a result of RNALater. I have syringed a sample ten times up and down in QiAzol solution to break it down. I think with skin tissue this will be even easier.

  • Mahendra Chordia added an answer in Immunology Techniques:
    How do I enhance surface expression of FPR1 on primary human neutrophils?

    I want to titrate my rabbit anti-human FPR1 antibody and would like to perform the titration on cells that I know strongly express FPR1 on their surface.

    Mahendra Chordia

    Yes  PMA should work fine too. Li Xiao reported ear lobe inflammation model for imaging using PMA, check the molecular imaging paper.

  • Krzysztof Korbel asked a question in Neurological:
    Does anyone have experience with SaeboFlex?

    Does anyone have experience with SaeboFlex in neurological hand treatment?

  • Andrew Ahmed asked a question in Learning:
    Where can I find trending topics and research on machine learning?

    I'd rather hear it from the experts in this subject, but I am going to look around "Cognitive Learning Applications" and other biological learning methods and it's application to technology. Although help from in field researchers would be great. Thanks!

  • V. P. N Nziko added an answer in Gaussian:
    Gaussian the error in link 716?

    While I put a job for Scan 2 molecules in gaussian the error 716 appeared. Could you please suggest how I can resolve it?


    V. P. N Nziko

    Explanation of Error
    This means that the Gaussian job terminated abnormally because an angle x in the z-matrix optimized to become outside the allowed range of 0 < x < 180.

    Fixing the Error
    This can happen if there are large geometry changes in a molecule, especially one composed of interacting fragments, and one must either re-define the z-matrix, or use a different coordinate system.

  • Alan Philip Garfinkel added an answer in 3D Visualization:
    What is the epistemic value of 3D visualization in archaeology and heritage?

    I am working on a theoretical analysis of the practice of 3D visualization of archaeological heritage and built heritage and am open to comments and suggestions.

    Alan Philip Garfinkel

    We think that 3-D documentation in rock art might be helpful as a means of capturing much of the data encompassed on a rock relating to the prehistoric image production.  It would be helpful for an interactive experience of a rock art site by those who are unable to directly and personally visit these locations.

    We have experimented with 3-D approach.  See our work on academia.edu

  • V. P. N Nziko added an answer in Gibbs Free Energy:
    How can I change gibbs free energy of rection from positive to negative in gaussian?


    I optimized all reactants and products. all frequencies and directions are correct but the delta G of reaction is positive. Delta G should be negative because the reaction is Automatically. I use B3LYP/6-31+G** and a have Se and S in my reactant and product

    V. P. N Nziko

    Remember a positive free energy does not mean the reaction doesn't take place it means the reaction is not spontaneous under the given conditions and in the set direction. So if you're free energy is positive it simply means you reaction is not spontaneous in that direction.