Nazanin Karimaghaei added an answer:How to quantify the effects of long term mild cold exposure while accounting for uncontrolled variables?
Does anybody have any experience on how to conduct clinically controlled trials on ordinary office workers with the intention of measuring the impacts of ambient temperatures? I am interested in developing a method for quantifying the effects of colder office environments aimed at studying how occupant thermogenesis adapts to compensate for lower zone temperatures.
One difficulty that I envisage is standardising the conditions and accounting for uncertainty. For instance assuming that as a result of spending two weeks in cooler offices, 10 subjects lose weight; whereas similar subjects in a warmer office maintain their initial body fat. But I have no control on the effects of life beyond their office environment, and how that can impact the results. Does anybody have any experience on how to create a level playing field when so many variables are concerned so that you can only narrow your results to talk about the effects of temperature in the office?
Really appreciate any thoughts…
Thanks for your insightful comments, yes you are right that establishing links between mild cold and occupant long-term response is going to be difficult. The offices are likely to be university buildings, with the potential of few commercial partners also joining up. Given that for a first phase we may not be able to have a large pool of volunteers, we may just repeat the trial on the same people, with two weeks of lower temperatures followed by two weeks of normal temperatures.
Grateful for your mention of sickness risks (dare I say over the Atlantic where you are people need to be more careful otherwise someone will sue!). I also think using motion sensing is a great idea, and I take note of the ‘controllable variables’ you mentioned.
As you both pointed out there are many confounding variables and with an intelligent trial design I might be able to find out few things about the effects on 1) body composition 2) increased resting thermogenesis 3) perhaps productivity (though it is very controversial).!
Thanks once moreFollowing
Kannadasan Narasimmarajan added an answer:How to monitor the estrous phases of a bat?
Is there a way to observe and document the varios phases of the estrous cycle in a wild female bat?
I think this is possible through urine and /or fecal matter analysis. one more way if time and FD permission permits you marked few females and recaptured through mist net and get blood or urine to do the analysis. if you willing to do through non-invasive technique urine or fecal is the best way to collect hormone data...Following
About Observation Medicine
Observation medicine is a medical service aimed at continued care of selected patients, usually for a period of 6 to 24 hours, to determine their need for inpatient admission. This service is usually provided in emergency departments.