Nuclear Medicine

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1 Can anyone help me with formula for calculating gastric emptying with solid food?
By Dinesh Rawat · Manipal University

Sujith P G · Tyndall National Institute

Only patients with Gastroparesis, show delayed emptying, especially to wards the end of the study, ie. after 2 hours. Please check clinical indication... [more]

Only patients with Gastroparesis, show delayed emptying, especially to wards the end of the study, ie. after 2 hours. Please check clinical indications of patients. Also, use a standard meal, ideally, Mashed potato, mixed with Tc Sulphur Colloid. Also patient has to stop few medications, before the study.

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24 What is the period of discharge of patients receiving Iodine131 for thyroid therapy?
By Said Kenida · ChuConstantine - enseignement

Lung-Kwang Pan · Central Taiwan University of Science and Technology

The biological half life for whole body and speciic thyroid is around 0.4-0.8d and 0.15-1.00d, respectively for thyroidectomy patients. The thyroid g... [more]

The biological half life for whole body and speciic thyroid is around 0.4-0.8d and 0.15-1.00d, respectively for thyroidectomy patients. The thyroid gland is largely removed for thyroidectomy patients, and thus the I-131 is remained mainly in the whole body. The internal dose thus comes from the whole body too. in such situation, the dose can be calculated by estimating the whole body as a homogenous water tank, then get the solution easily.

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1 Could anyone share his experience in calculating the 99m-Tc-mebrofenine uptake rate to evaluate hepatic function with hepatobilary scintigraphy?
By Emmanuel Deshayes · CRLC Val d'Aurelle

Ramin Sadeghi · Mashhad University of Medical Sciences

There are many ways to analyse the hepatic function by semi-quantitative methods. Recently, our research center performed an meta-analysis and you can... [more]

There are many ways to analyse the hepatic function by semi-quantitative methods. Recently, our research center performed an meta-analysis and you can find several methods in the Table 1 of this study.

Accuracy of hepatobiliary scintigraphy for differentiation of neonatal hepatitis from biliary atresia systematic review and metaanalysis of the literature.pdf ×

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Question:
Open In PET images, with the current methods of reconstruction, it is still a necessary denoising step?
If so, what is the most common method for denoising?

If so, what is the most common method for denoising?

By Jose Mejia · Universidad Autónoma de Ciudad Juárez

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1 Can anyone help me to find a research tool to assess discomfort when performing ROLL (radionuclide occult lesion localisation) rather than pain?
By Janica Mercieca · University of Malta

Rohan Khandelwal · Narayana Hrudayalaya Hospitals

Pain is the only problem at the time of injection of the radionucleotide. Other than that the procedure is not associated with much discomfort.

Pain is the only problem at the time of injection of the radionucleotide. Other than that the procedure is not associated with much discomfort.

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2 Is there a method to radiolabel Iloprost, sildenafil or Cyclosporin with a gamma emitter or a positron emitter?
By Manoj Bhatt · Townsville Hospital

Manoj Bhatt · Townsville Hospital

Dear Anna, I will try to send some links on these drugs with structure. Would there be a preferred email? Thanks, Manoj

Dear Anna, I will try to send some links on these drugs with structure. Would there be a preferred email? Thanks, Manoj

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6 Do we need the Society of Nuclear Medicine (SNM) Guidelines? As the survey shows that a good percentage of institutions do not follow them.
By Robert Njoagwuani · Mercy University Hospital

Robert Njoagwuani · Mercy University Hospital

Just to mention that Guidelines are Guidelines, they are recommendations / suggestions and are not strictly binding. Lawyers would tell you that yo... [more]

Just to mention that Guidelines are Guidelines, they are recommendations / suggestions and are not strictly binding. Lawyers would tell you that you do not win a suit strictly based on them. Protocols are different as they outline to you what you are expected do during a procedure/study. This is not to relegate the importance of the SNM and like bodies, they are very useful bodies but my argument is you to not base your practice strictly on their guidelines. These Guidelines can be modified to suit different patient or a particular situation during a study.

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4 Interested in working on computer models for myocardial viability? Any takers?
By Henry Levenson · University of Southern California

Henry Levenson · University of Southern California

I believe simply labeling something "viable" is inadequate. It has to be evidence based to justify the idea of what is best to define to define myocar... [more]

I believe simply labeling something "viable" is inadequate. It has to be evidence based to justify the idea of what is best to define to define myocardial viability using the constraint of a model. However, technology would vary in many parts of the world so some models would be more accurate than other. As you describe, the model could include functional recovery of the myocardium before or after coronary revascularization, ECG, echocardiogram, arrhythmogenity, myocardial response to exercise, image evaluation with nuclear or MRI imaging. Essentially, a multivariate model would essentially describe what is myocardial viability and would give a a statistical answer to this semantic enigma. I would suggest using a retrospective study using data already available in population groups with cardiac disease in humans.

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7 Total number of radioiodine treatments in the USA, EU or Worldwide?
By Jeppe la Cour · Glostrup Hospital

Jeppe la Cour · Glostrup Hospital

Most help full comments with the pin point of the table - I found the number of treaments for hyperthyroidsm and thyroid cancer. Now I can say that th... [more]

Most help full comments with the pin point of the table - I found the number of treaments for hyperthyroidsm and thyroid cancer. Now I can say that the number of treatments is at least xx/million. I hope to find the numbers for treament of goiters too. First time using RG question and I'm impressed.

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Answer added to:
6 Anybody here working on a production facility of a Mo-99/Tc-99m generator?
By Denis Aquino · Philippine Nuclear Research Institute

Lidia Matei · Best Theratronics Ltd

in Hungary at Budapest - Izotop 1121 Budapest, Konkoly Thege Miklós út 29-33 in US Covidien... in Canada Lantheus.. in Korea... in South Afric... [more]

in Hungary at Budapest - Izotop 1121 Budapest, Konkoly Thege Miklós út 29-33 in US Covidien... in Canada Lantheus.. in Korea... in South Africa.. On IAEA documents you find all Mo99/Tc99m producers... Good luck

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Answer added to:
1 How do you consider the individual absorbed doses of non-target organs in thyroid gland radiation therapy?

Jerry Battista · The University of Western Ontario

Your best approach is to use the MIRD method of radionuclide dose calculation published in a series of "MIRD pamphlets" by the Society of Nuclear Medi... [more]

Your best approach is to use the MIRD method of radionuclide dose calculation published in a series of "MIRD pamphlets" by the Society of Nuclear Medicine. These contain Tables of physical factors for paired "source" and "destination" organs. You account for the nuclear decay scheme of the isotope and need to know the biodistribution and clearance of the pharmaceutical (biological half life). For I131 thyroid, there is a rich literature and relevant data sets. Search "MIRD Pamphlets"...and they should all appear. Some may require $. Refresher courses (PowerPoint) are usually free. The more sophisticated approach uses the Monte Carlo method but that's an order of magnitude more complex and slower. A "Nuclear Medicine" hospital physicist is your best helper. J2

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2 Can we fractionate to smallest activities (1000 MBq) for a patient with renal failure and which precautions during hemodialysis session?
By Said Kenida · ChuConstantine - enseignement

Ceferino Gutierrez Mendiguchia · Hospital Povisa

Dear Dr. kenida. I think that in these patients, we must reduce the 131-I dosage because radio-iodine recirculation is present and the whole body irr... [more]

Dear Dr. kenida. I think that in these patients, we must reduce the 131-I dosage because radio-iodine recirculation is present and the whole body irradiation and the red bone marrow doses are 3-5 times higher. Also, if we fraccionate the dose, we have to considerate the high probability of thiyoid stunning and thus, we could be not to achieve a enough amount of radioactivity in the remnant thyroid tissue.

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1 Welcome! :) / Logo
By Wolfgang Bergter · Martin-Luther-Universität Halle-Wittenberg

Wolfgang Bergter · Martin-Luther-Universität Halle-Wittenberg

In the meantime I changed tho logo of our group.This ist what we are dealing with: high end technology for the benefit of our patients.

In the meantime I changed tho logo of our group.This ist what we are dealing with: high end technology for the benefit of our patients.

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Answer added to:
8 Is there any experimental or computational basis for release of radioactivity in environment from production of Tc-99m generator?
By Denis Aquino · Philippine Nuclear Research Institute

James Secrest · Biotech-Net.com

If I find somthing else I'll let you know. Are you on LinkedIn ?

If I find somthing else I'll let you know. Are you on LinkedIn ?

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About Nuclear Medicine

A specialty field of radiology concerned with diagnostic, therapeutic, and investigative use of radioactive compounds in a pharmaceutical form.

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