Nephrology is a branch of internal medicine dealing with the study of the function and diseases of the kidney.

• Mallikarjun Jaji

  Animal model of kidney fibrosis

  I want to know the animal model of kidney fibrosis in diabetes, my question is if you have any idea about how to develop a kidney fibrosis model in mice economically?

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  • 
    John Leader replied

    Post mortem.

    3 days ago
• um Mariam

  Is Innohep (low molecular weight heparin) or heparin better for haemodialysis patients and why?

  Most patients in our unit are on heparin which causes thrombocytopenia to some patients.

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    Sameer Alarrayed replied

    Use of low molecular weight heparin for hemodialysis: a short-term study. Sameer Al-Arrayed, Rajagopalan Seshadri Saudi journal of kidney diseases and transplantation : an official publication ofUse of low molecular weight heparin for hemodialysis: a short-term study. Sameer Al-Arrayed, Rajagopalan Seshadri Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia. 13(2):146-50.

    8 days ago
• Preeti Bommannavar

  Do antioxidant agents aid in reducing nephrotoxicity?

  Specifically in regards to nephrotoxicity induced by aminoglycosides and their mechanism of action.

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    Nikolaos Tzenakis replied

    It may be helpful. No RCT'S has published yet.in a point of view that it is not harmful you can be used in your pts

    19 days ago
• Joachim Beige

  Peritoneal dialysis in rare metabolic disorders

  There is scarce literature data on the use of peritoneal dialysis in rare metabolic disorders like primary hyperoxaluria, Fabry´s disease or hyperamonemia. Who has some systematic experience on thisThere is scarce literature data on the use of peritoneal dialysis in rare metabolic disorders like primary hyperoxaluria, Fabry´s disease or hyperamonemia. Who has some systematic experience on this issues?

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    Michael L Moritz replied

    Primary hyperoxaluriua requires aliver transplant, but prior to that being available you need frequent hemodialysis 5 - 6 days a week and the addition of nightly peritoneal dialysis ifPrimary hyperoxaluriua requires aliver transplant, but prior to that being available you need frequent hemodialysis 5 - 6 days a week and the addition of nightly peritoneal dialysis if possible/practical. Acute hyperammonemia requires hemodialysis or CRRT. In Farbry's disease dialysis is indicated for the treatment of ESRD but it does not affect the course fo the disease and is not indicated for Fabry's disease in the absence of ESRD. Hope's this is helpful. Michael Moritz

    20 days ago
• Preeti Bommannavar

  Is diuretic activity important in reducing nephrotoxicity and nephritis?

  What is the mechanism in reducing the above problems? Nephrotoxcity induced by gentamicine.

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    Marcelo Tavares replied

    Activation of RAAS is complex and is related not only to hypertension per se but also (in the particular case of ADPKD) to cysts growth. This article (Activation of RAAS is complex and is related not only to hypertension per se but also (in the particular case of ADPKD) to cysts growth. This article ( http://cjasn.asnjournals.org/content/3/4/1197.full ) is free for download and shos some particularities concerning this disease, including RAAS. Hpe you enjoy. Best regards.

    25 days ago
• Rafael José Vargas Alves

  I have a case report of Oligomeganephronia in adult. Does anyone have a suggestion on which journal I could submit it to?

  Oligomeganephronia is a type of renal hypoplasia characterized by a severe developmental defect in both kidneys and the following histopathologic features: low number of nephrons, hypertrophicOligomeganephronia is a type of renal hypoplasia characterized by a severe developmental defect in both kidneys and the following histopathologic features: low number of nephrons, hypertrophic glomeruli and hypertrophic tubules .

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    Jeetendra Rathod replied

    May I ask you about the interesting association with this histological picture and the disorder you have found, has it been reported previously?

    Apr 24, 2012
• Marsida Kasa

  Carperitide (Atrial Natriuretic Peptide) experience.

  I’m very interested in sharing some practical experience with low-dose Carperitide (atrial natriuretic peptide) infusion in patient undergoing CABG or its usage in prevention contrast inducedI’m very interested in sharing some practical experience with low-dose Carperitide (atrial natriuretic peptide) infusion in patient undergoing CABG or its usage in prevention contrast induced nephropathy. Can anyone tell me the cost and dosage of this treatment, and did you use it as a standard therapy?

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    Kunio Misono replied

    I am a basic science researcher so that have no practical experience. You probably know this paper. In any case, I too am very interested in knowing the clinical utility of natriureticI am a basic science researcher so that have no practical experience. You probably know this paper. In any case, I too am very interested in knowing the clinical utility of natriuretic peptides. Renal protective effects and the prevention of contrast-induced nephropathy by atrial natriuretic peptide. Morikawa S, Sone T, Tsuboi H, Mukawa H, Morishima I, Uesugi M, Morita Y, Numaguchi Y, Okumura K, Murohara T. J Am Coll Cardiol. 2009 Mar 24;53(12):1040-6. Erratum in: J Am Coll Cardiol. 2009 Sep 15;54(12):1122.

    Apr 19, 2012
• Noemí Esparza

  Do you treat mild subclinical hypotiroidism (TSH < 10) in patients with diabetic nephropathy?

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    Isnail Ibrahim replied

    NO, AN APPROACH OF TADE-OFF should be adopted; otherwise there will be RAPID DECLINE OF KIDNEY FUNCTION (RDKF) and creeping up of creatinine through upgrading the metablic pathways... However, INO, AN APPROACH OF TADE-OFF should be adopted; otherwise there will be RAPID DECLINE OF KIDNEY FUNCTION (RDKF) and creeping up of creatinine through upgrading the metablic pathways... However, I would cautiously treat them if they have intractable constipation or other vague glaring symptoms warranting hormonal replacement therapy to be instituted... Needless to reemphasize the paramount importance of following those patients from cardiological point of view in parallel which may unequivocally advocate which way to go... By the end of the day, personalization of management should be pursued... Ismail Ibrahim

    Apr 12, 2012
• Nikola Pavlovic

  Balkan Endemic Nephropathy (BEN) patients

  Is anyone interested in looking at genetics in Balkan Endemic Nephropathy (BEN) patients? Many researchers believe that genetic predisposition may play a crucial role in the etiology of BEN providedIs anyone interested in looking at genetics in Balkan Endemic Nephropathy (BEN) patients? Many researchers believe that genetic predisposition may play a crucial role in the etiology of BEN provided there are some environmental factors present as well (aristolochic acid, ochratoxin A, organics etc). Doing GWAS or exome sequencing could give the clue for solving the problem of BEN etiology.

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    Francesco Paolo Schena replied

    I am not involved in Balkany nephropathy

    Mar 24, 2012
• Abduzhappar Gaipov

  Is there any case of late recovery of one of the two kidneys after AKI?

  We have a case of AKI developed after unilateral per cutaneous contacted lithotripsy with anuria about 2 weeks and intacted kidney recovered after 8-10 days then affected kidney (stoned kidney).We have a case of AKI developed after unilateral per cutaneous contacted lithotripsy with anuria about 2 weeks and intacted kidney recovered after 8-10 days then affected kidney (stoned kidney). What was the mechanism?
• Zewdneh Shewamene

  Looking co-advisor

  Hello dear fellows, I need to ask those of you who are interested to co-advise my research on RENAL EFFECTS OF KHAT (Catha edulis forsk) in rats

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  • 
    Prof.Trushakant Narayanrao Patil replied

    I shall be more than happy to be associated with this event.Please do correspond with me. Prof.T.N.Patil.Biochemistry,St.James School of Medicine ,AnguillaI shall be more than happy to be associated with this event.Please do correspond with me. Prof.T.N.Patil.Biochemistry,St.James School of Medicine ,Anguilla ,BWI.Email:patiltruna@gmail.com,Ph.+12645825551

    Nov 19, 2011
• Ziyong Tang

  Is there anyone interested in the nephrology of the elders?

  I am interested in the aging of the kidney and sure of that it is important to distinguish the process of fibrosis and aging.

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    Zhangxue Hu replied

    It is very dificult to differentiate loss of renal function from aging or fibrosis caused by unknown reasons. It is also hard to develope a animal model mimic aging because animal models are oftenIt is very dificult to differentiate loss of renal function from aging or fibrosis caused by unknown reasons. It is also hard to develope a animal model mimic aging because animal models are often short-time.

    Nov 7, 2011
• Rolando Milian

  What is a loopagram in a kidney test?

  where can I find information about it? I would greatly appreciate it any help with this. Thanks

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  • 
    Deepak Sharma replied

    loopogram is a test wherein a contrasr dye is put and a scan is taken to check the patency of kidney tube or that of an artificial urinary bladder made out of small intestine in some patients. Iloopogram is a test wherein a contrasr dye is put and a scan is taken to check the patency of kidney tube or that of an artificial urinary bladder made out of small intestine in some patients. I hope this answers your question. you are welcome to ask any further query on this

    Oct 12, 2011