Study of interactions between nanomaterials and biological systems

• Mini MS

  Toxic effects of silver nanoparticles

  Silver nanoparticles can be synthesized by both biological & chemical means. Is it true that in general, nanoparticles synthesized by chemical means are more toxic? How is this possible whenSilver nanoparticles can be synthesized by both biological & chemical means. Is it true that in general, nanoparticles synthesized by chemical means are more toxic? How is this possible when regardless of the means of synthesis, the structural and other aspects remain the same?

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    Seyed Ali Johari replied

    Please See Our last paper about your question in following link: Toxicity of various silver nanoparticles compared to silver ions in DaphniaPlease See Our last paper about your question in following link: Toxicity of various silver nanoparticles compared to silver ions in Daphnia magna http://www.jnanobiotechnology.com/content/10/1/14/abstract

    Apr 17, 2012

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    Stephan Barcikowski replied

    does the nickel nanoparticles or the nickel ions released/dissolved from the particles determine the toxicity? In our case, the medium played an important role, and we thick it is more likely thedoes the nickel nanoparticles or the nickel ions released/dissolved from the particles determine the toxicity? In our case, the medium played an important role, and we thick it is more likely the ions that reduce cell viability: Hahn, A. ; Fuhlrott, J. ; Loos, A. ; BARCIKOWSKI, S.: Cytotoxicity and ion release of alloy nanoparticles. In: Journal of Nanoparticle Research 14 (2012), Nr. 1, S. 686–695 and BARCIKOWSKI, S. ; Hahn, A. ; Guggenheim, M. ; Reimers, K. ; Ostendorf, A.: Biocompatibility of nanoactuators: stem cell growth on laser generated nickel titanium shape memory alloy nanoparticles. In: Journal of Nanoparticle Research 12 (2010), Nr. 5, S. 1733–1742

    Apr 16, 2012
• Jawahar Sharma

  Nanotoxicology of metals

  How nanoparticles can be used to improve the medicinal values

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    Stephan Barcikowski replied

    for nano-gold, there are multiple examples, e.g. in cancer taregting, transfection or reproduction biotechnology, see: Prostate Canter Targeting: Walter, J. ; Petersen, S. ; Stahl, F. ; Scheper, T.for nano-gold, there are multiple examples, e.g. in cancer taregting, transfection or reproduction biotechnology, see: Prostate Canter Targeting: Walter, J. ; Petersen, S. ; Stahl, F. ; Scheper, T. ; BARCIKOWSKI, S.: Laser Ablation-Based One-Step Generation and Bio-Functionalization of Gold Nanoparticles Conjugated with Aptamers. In: Journal of Nanobiotechnology 8 (2010), Nr. 21, S. 1–11 Transfection: Duran, M. C. ; Willenbrock, S. ; Barchanski, A. ; Mueller, J. M. V. ; Maiolini, A. ; Soller, J. T. ; BARCIKOWSKI, S. ; Nolte, I. ; Feige, K. ; Escobar, H. M.: Comparison of nanoparticle-mediated transfection methods for DNA expression plasmids: efficiency and cytotoxicity. In: Journal of Nanobiotechnology 9 (2011), Nr. 47, S. 1–11 Application prospects in reproduction biology Barchanski, A. ; Taylor, U. ; Klein, S. ; Petersen, S. ; Rath, D. ; BARCIKOWSKI, S.: Golden Perspective: Application of Laser-Generated Gold Nanoparticle Conjugates in Reproductive Biology. In: Reproduction in Domestic Animals 46 (2011), Nr. 3, S. 42–52

    Apr 16, 2012
• Jason Patocka

  National Academy Publishes New Nanomaterials Risk Research Strategy

  http://2020science.org/2012/01/25/national-academy-publishes-new-nanomaterials-risk-research-strategy/
• Ibrahim Rabea Elsebaey

  I'm using hydrophobic nanosilica as mosquito larvicides. Can you suggest non-toxic solvent to perform the bio-assay test?

  Hydrophobic nanosilica are synthesized by my college chemistry team in Ain Shams University, Egypt. These particles are not soluble in either water or available organic solvents as ethyl alcohol orHydrophobic nanosilica are synthesized by my college chemistry team in Ain Shams University, Egypt. These particles are not soluble in either water or available organic solvents as ethyl alcohol or acetone. How can I to dissolve them to make different concentrations for the bio-assay test?

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    Ibrahim Rabea Elsebaey replied

    Abdul Manaf Ali Thank You very much. I appreciate your advice

    Jan 14, 2012
• Ivan Quevedo

  Physicochemical characterization of nanoparticles

  Could anybody suggest in the best method to characterize fluorescent nanoparticles in solution? Light Scattering Methods are not exactly the best for this purpose. Thanks!

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    D. R. Mahadeshwara Prasad replied

    Depending on the Size Range often separation techniques are used to discriminate fluorescent nanoparticles Analytical Techniques: Dynamic Light Scattering (DLS) Multi-Angle Light LaserDepending on the Size Range often separation techniques are used to discriminate fluorescent nanoparticles Analytical Techniques: Dynamic Light Scattering (DLS) Multi-Angle Light Laser Scattering (MALLS) UV Spectroscopy Light Obscuration Micro-Flow Imaging (MFI) Nanoparticle Tracking Analysis (NTA) Separation techniques: Size Exclusion Chromatography (SEC) Field Flow Fractionation (FFF) Capillary Electrophoresis. (CE) Analytical Ultracentrifugation (AUC)

    Oct 26, 2011
• Gaber Hussein

  Does anyone have experience with Micromaster440?

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    Seyed Ali Johari replied

    Hello, I measured the absorbance of my samples using a Spectra-MAX-PLUS 384 UV–visible spectrophotometer (Molecular Devices, USA) in a range of 190-1000 nm. I have different colloids of silverHello, I measured the absorbance of my samples using a Spectra-MAX-PLUS 384 UV–visible spectrophotometer (Molecular Devices, USA) in a range of 190-1000 nm. I have different colloids of silver nanoparticles and their absorbance peak is around 420-430nm. But one of my sample which is a suspension of one type of silver nanoparticles give a very different peak in 320nm (reverse peak!), I can not interpret and understand why this is difference? Can you please interpret it for me? please look at the attached file. Best regards, Ali

    Aug 15, 2011
• Adolph Anga Muleja

  Functionalization of MWCNTs

  What do you think of XPS being considered as the ultimate technique to prove the successful synthesis of functionalized CNTs?

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    Srivatsan Parthasarathy replied

    Detection of surface moieties have always been a soul motive of XPS. Active mechanism of functionalisation is to attach a functional group or moiety over CNT. any change in the surfaceDetection of surface moieties have always been a soul motive of XPS. Active mechanism of functionalisation is to attach a functional group or moiety over CNT. any change in the surface characteristics of CNT can be inferred as the functionalisation of the same. To be more specific, data on the pie- electron characteristic of the functional group to be added can be compared with that of the functionalised CNT XPS SPECTRA to confirm the functionalisation with the particlar group

    Jun 5, 2010

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• Kalpana Sastry

  Any reports of toxicology of nanomaterials in agriculture?

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