Is there any software method to detect breast cancer in early stage?

To Dr. Kayar: what kind of breast cancer markers are currently used to judge malignancy in case of stage null cases? I am asking this because I feel serious communication gap between experienced medical teams with research communities.We need to go for stage I-III trials for various therapeutic applications on which we are getting result in vivo in research, provided we know clearly, which one is currently being used by medical community in which stage of cancer and what is the statistics of 5-year survival in those patients.

precancerous(florid epithelial hyperplasia) and/or preinvasive (IN SITU) breast lesions are often greater than 1cm

Related with the question of SENGUPTA:
Stage 0(NULL) breast cancer:a nonpalpable lesion smaller than 1 cm.

scintimammography ,using 99mtc(V)-dmsa or99mtc-MIBI,with high sensitivity,specificity,acurracy,PPV and NPV.

There were happy times when medicine was evidence-based, but even then there were always two roads: aggressive treatment or active observation. Usually the patient's opinion is taken into consideration: can they live with "precancerous"lesions and be happy (I know I can, especially with all the imaging techniques we have) , or it would poison their mind and they usually insist on immediate removal/aggressive treatment of the suspicious spot. The more is the danger of cancer, the more one chooses to undergo treatment (e.g., bilateral mastectomy, better scars, than death). However, Steve Jobs postponed his treatment for 9 months which he regretted later (as I read). Anyway, what I am trying to say is that "early" cancer and "pre-cancer" is close, but not necessarily stages of the same process. Something should go really wrong (on molecular level) to allow cancer to develop. Just imagine millions of cancer-initiating cells in your body appearing every minute, and how many of then will make it? To Zuzanna Mooore: what life style changes did you undertake to improve defense system?

"I think breast cancer detections needs a multi-way approach"- Debomita Sengupta
I couldn't agree more! By using all possible imaging methods (PET/CT, digital mammo, thermography, ultrasound) and CA 27 29 plus CRP as a general indicator of inflammation, I was able to detect, what I think is a "precancerous" condition in my breast. I did all of these because of some alarming phenotyping expression. Using imaging AND labs combined seems to be most effective for early detection, as it allows to discover areas of hypervascularity and confirm with the BC markers. Yes, not much can be done surgically, or chemo/rad methods at this stage, but we can address the "terrain" ie. using nutrition and life style changes to effectively modulate genetic expression. BC is a systemic disease, so focusing on the entire body makes quite a bit of sense although is not accepted in medical practice today. That could also be effective for mutation carriers who may not want to be mutilated at the age of 20 (!). For Veronika Mamaeva: here is the link worth pondering: www.scarprojejct.org, not a science but art that speaks volumes.

If I may say from the health care provider point of view, frankly if the tumor is detected on mammography its already too late. With the right training any woman should be able to do self check, even with big breast. Overall awareness and self check among women of different age is much more efficient that screening which is however a must. And of course, mutation carriers should have preventive mastectomy in their 20th.

mammography is the principal test for screening , in the last years mammography pased technogic improvement ' tomsynthesis ' contrast enhaced mammography .
ultrasuond is complenetary test after mammography for analizing masses detected by mammography or by clinical examination specialment pragnant and yuong women /
MRI is other madality for women with dense breast ' and yuong with family hiasory or genetic BRCA 1 2

Dear Sir,

As per my idea, malignant tumors are by nature itself, metastatic/invasive.But don't you think, if we can destroy them before reaching the connective tissue/lymph node in case of breast cancer, it is possible to get rid of them, provided that you have considered all the routes of probable metastasis?Because that's where the importance of early detection lies.

Another question, which kind of cases will you consider stage null?

dear friend
as a 38 year-breast surgeon and surgical oncologist,ı find "early breast cancer" term is an old one .it ignores the modern view on breast cancer:if a br.cancer is an agressive type(as molecular subtype),there is no advantage to catch it early.it is usually chemo-radioresistant .Any treatment modalities can not change its very poor outcome.
Conversely,if it is slow or medium type cancer ,it will give a pretty long time to be diagnosed early.
The problem is,the percentage of stage null cases among newly diagnosed breast cancer patient.e.g.,
this rate is 5-10 % in my country(TURKEY) ,while the same rate is about 48 % in USA !...
that's the most important point on this subject,ı think.

Mammography is general esam for screening for breast cancer . ultrasuond is complenentery exam for yuong and pregnant women mri for dense breast for women with family history and BRCA1 2

I think breast cancer detections needs a multi-way approach.You need to consider size of the tumor to initiate.It will give you an idea whether this size is considerable for adjacent lymph node metastasis.Apart from histological approaches, you also need to confirm expressions of breast cancer markers.

I think that thermography is a valid detection method if the tumor is close to the surface of the breast, but it is not a good method for deep tumors. I have been working with ultrasound detection methods that essentially use strain-imaging to detect stiff material in the breast, such as a tumor. If you would like to hear more about this, please feel free to email me. Good luck!

Austin

Mammography and ultrasonography are validated methods for diagnostic and screening of breast cancer. Another think is how to study the characteristics, and the prognosis.

I'm working on a study approaching the problem within RGB space. By now the results seems to be interesting...I'll update you when I'll be able to say you more about it.