- Beatrice Muraguri added an answer:8What are some of the major domestic ethical issues that have arisen in the recent Ebola epidemic?
Lots has been written about quarantine and closing borders domestically (US) but not much else.
Scientists tell us that EVD can still be in the semen for 90 days.We have heard of stories where male survivors forcefully sleep with their wives which is against the advice they receive during discharge.The wives ends up being infected and die another ethical issueFollowing
- Muhammad Belal Hossain added an answer:5Is MERS CoV transmitted by the one humped camel (camelus dromedaries)?Mers
Yes, it is evident in some research conducted in middle eastern countries like UAE, KSA etc. Sero-positivity showed the exposure of MERS-CoV in their lifetime.Following
- Peizhong Peter Wang added an answer:16Is it possible to test for significance between medians of two groups?To perform a test of significance between means of two groups is well known. But if I use the medians is it possible to test for significance between medians of two groups?
This was I did in one of my papers (PMID 12677268): Can J Gastroenterol. 2003 Mar;17(3):183-6.
"The 95% CI for means were calculated using the conventional normal distribution method. Because there is no available statistical formula to directly calculate the 95% CI for medians, a bootstrap approach was employed (7,8). This technique involved dividing the total participants into subgroups (replicates), from which a random sample is taken with replacement and a new median was calculated each time. After a large number of such experiments, the lower and upper 95% CI were determined from the values at 2.5% and 97.5% percentiles. All the calculations were performed using SAS 8.0 (SAS, USA)"Following
- Kisia Abok added an answer:2Does the MACS cohort data include any information about the health status or mortality of primary partners?
I have read through the forms and documentation for the Multicenter AIDS Cohort Study several times, and I am not seeing any health data about life partners having been captured. Regarding "blood relatives," there is some. I would assume that this is a result of "no promo homo."
This hasn't been a bad dream, has it?
I observed several inhabitants living along lake victoria shores who I accidentally know to be HIV positive but they do not know that they are HIV positive and I have advised them to eat plenty of fish and vegetables,and immediately seek medical treatment for any infection. They are healthy and I shall soon invite them for couselling??Following
- Ann Meadow added an answer:11What variables inside a database represent a patient's socioeconomic status in administrative claims database research?
When we want to define the socioeconomic state of an enrollee, what variables (items or data) should we look at and collect?
Measures are poor, and I tend to agree with Frost. May try address linked to small-area income/poverty rate data (see Hall above); health insurance status/type of health insurance, depending on the circumstances.Following
- Sharon Lawn added an answer:2What is the best measure to rate the core factors influencing the management burden issues that patients with long term conditions are reporting?
Patients are reporting issues such as poor access to care, availability of socio-economic resources and time; knowledge; and emotional and physical energy. (Bee et al. 2014)
The work patients must do to care for their health; problem-focused strategies and tools to facilitate the work of self-care; and factors that exacerbate the burden felt (Eton et al 2014)
Capacity, responsibility, and motivation: a critical qualitative evaluation of patient and practitioner views about barriers to self-management in people with multimorbidity. BMC Health Services Research (Impact Factor: 1.77). 11/2014; 14::536. DOI: 10.1186/s12913-014-0536-y
Building a measurement framework of burden of treatment in complex patients with chronic conditions: a qualitative study. Patient Related Outcome Measures 2012:3 39–49 http://dx.doi.org/10.2147/PROM.S34681
Have you considered the first tool within the Flinders Program - Chronic Condition Care Planning? You'll find details about it at: http://www.flinders.edu.au/medicine/sites/fhbhru/self-management.cfm
It's called the 'Partners in Health Scale' and it's a 12 item measure that the person self-rates re their knowledge, relationship with health professionals, access, monitoring and responding, physical, social and emotional impacts, lifestyle, etc. The tool has been validated and used in many research trials and in practice as either a standalone to measure change over time, determine client groupings, determine for services which clients would benefit from care planning, etc.
It has been adapted into other languages and used in the US, NZ, Australia, Hong Kong and some other countries.Following
- Saleh Ameer added an answer:6Why two groups with same median shows significant difference when using Wilcoxon signed rank test or Mann-Whitney u test?Whether the non parametric tests are designed properly?
Sorry I only just saw the date of the q.
A bit late I guess :)Following
- Olubusayo Akinola added an answer:4Can perception of role be independent of exhibited attitude?
In a sample of healthcare workers, it was deduced that exhibited attitude towards performing a role differs from their perception towards taking up that particular role in a hospital establishment.
Although this sample exhibited a negative attitude, they had positive perception of their role. It seems to me however, that perception and attitude should go hand in hand, and this sample defies my thinking. Any help?
Thanks for your prompt response to my question. The two independent variables for the study in question is perception and attitude. Measured with two different validated instruments, one specifically designed to access attitude and the other measures perception. The responses to the questions are Likert scaled.Following
- Manpreet Khurmi added an answer:95Disease causing Suicidal deaths ?Dear Researcher,
I am very eager to know the answer for this research question.
What are the disease that can lead to increase the suicidal intend of the patient. Because, I had seen a good number of cases of the patients of HIV/AIDS patients commiting suicide due to lack of hope on the life expectecation, social discrimination, compramised life and Family isolations. But as the same, there may be many disease that which can turns the patient mind into suicidal corner.
Please share the answer for my question. I would be very happy if anyone interested to share some of the articles and data of the same mentioned above.
Broadly speaking, Suicides are seen in pts with Chronic depression, Patients on Terminal illnesses etc. However, one needs to differentiate between attempted suicide and a successful suicide as attempt to suicide could be related to heat of the moment e.g. a students who learns he has failed in an exam. Do see these articles that may answer your query:
1. Leading causes of death in US: http://www.cdc.gov/nchs/data/nvsr/nvsr61/nvsr61_04.pdf (Suicide is at 10th)
2. Vulnerability to suicide: http://www.nhs.uk/Conditions/Suicide/Pages/Causes.aspx
3. Low serotonin levels and suicide: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819157/
As a research topic, one should differentiate between Trigger due to Physiological/ Stress (in absence of any pathological condition) reasons and Suicide related to Background of any pathological condition (mental, chronic illness, neoplasia etc). As a secondly aim, mode of execution of suicide may also be studied.
Hope this helps!
- Manpreet Khurmi added an answer:10Is it necessary to make the medical records data electronic in hospitals in developing countries? What are the benefits?In Nepal, most of the hospital's records are disposed of after 5 years, so data is also disposed of. Is it correct to do this? Should it be made electronic? Should Bio-statisticians play a role?
It is important to make Hospital Data electronic. Just sharing some random thoughts:
1. Epidemiological Information: Who knows which part of the world has the highest burden of the disease? Incidences like Minamata disease just point out to this epidemiological correlate.
2. In countries where large number of clinical trials are on-going, such information is highly valuable to identify patients who need newer drugs and can benefit from newer treatment regimens.
3. Patients who are allergic to a particular drug (or inborn errors of metabolism) could easily be maintained in such clinical histories e.g. sulphonamides.
4. Such information can help Government to develop Targeted Behaviour Change Communication strategies to change unwanted behaviours.
5. Can help health financing that is set aside required budget to address health needs of the population e.g. Incidence of Cleft lip/ palate as part of National programme of the country e.g. Rashtriya Bal Swasthya Karyakram.
6. Obstetric History: Impact on next pregnancy
7. Vaccination history: I need not emphasize more
Do Note: Patient history is confidential. In no case this should be made public and should be free form data theft.
- Lateef Mtima added an answer:22What types of intellectual creations can be the subject matter of IP?
The history of the human race is a history of the application of imagination, or innovation and creativity, to an existing base of knowledge in order to solve problems or express thoughts. From early writing in Mesopotamia, the Chinese abacus, the Syrian astrolabe, the ancient observatories of India, the Gutenberg printing press, the internal combustion engine, penicillin, plant medicines and cures in Southern Africa, the transistor, semiconductor nanotechnology, recombinant DNA drugs, and countless other discoveries and innovations, it has been the imagination of the world's creators that has enabled humanity to advance to today's levels of technological progress. I am interested in determining what type of intellectual creations can be the subject matter of IP?
To provide a non-political answer to the question, today most nations recognize IP protection for utilitarian innovation (machines, drugs, some times methods of doing business) under patent and/or trade secret regimes; for original creative expression (books, art, music) under copyright regimes; restricting commercial exploitation of an individual's name, likeness, or persona under publicity rights (not as widely recognized as other forms of IP); and for distinctive source indicators of products or services under trademark regimes. Those are the major categories of innovative or creative output typically recognized as IP; the key is fitting the out put into one of these regimes AND satisfying the regime's particular prerequisites to protection (for example, in the US, fixation in a tangible medium such as on paper or film is a prerequisite to copyright protection, which is not the case for some other copyright regimes).Following
- Olubusayo Akinola added an answer:6Can I compare the results of a PCA from a study with mine using the same questionnaire?
I would like to know if its possible to compare the factor loadings obtained from a particular survey with mine using the same questionnaire. This is to enable me to establish the variables capable of explaining the observed variance in my study and to confirm if there are differences in the item loadings.
Thank you Dr Filipe for being so explicit, I found the links very useful and I feel more confident to continue with my analysis. I also appreciate Prof David, it's a privilege that you look through my questions. Thank you.Following
- Paresh Chandra Ghosh added an answer:18Has anyone examined the effect of breast size on the biomechanics of lifting in industry or health care?
Seems like women with larger breasts would have to carry objects further from the body, with effects on lifting efficacy. But I can't find anything about this.
Yes I do agree with myor her view is considerate.let us leave together some disadvantage of this nature man can help women so peaceful co existence is best. Beside pursue some research to really understand it is problem or not. pcg ChennaiFollowing
- Sandro Rolesu added an answer:16How does one link altitude to a dataset containing latitude and longitude?
I would like to analyse my data by altitude, however I do not have this information in my dataset. Latitude and longitude are recorded. Is there a look-up table which would allow me to link this to altitude?
Edited for clarification: I am using Health Survey data. I would like to examine various participant characteristics by altitude. I have the latitude and longitude for addresses of all the respondents in my survey data. I do not have any data on altitude. Does a dataset exist that is open-access, that I could download and use to link altitude to my existing data?
You can download altimetry 30x30 meters (ASTER GDEM data) based on satellite observation, at the link: http://www.jspacesystems.or.jp/ersdac/GDEM/E/4.htmlFollowing
- Ali Abdil Razzaq Muhammed Noori Aldallal added an answer:4Where we can get a current epidemiological status of obesity and insulin resistance?Is there any specific site for current epidemiological status?Following
- Avi Biswas added an answer:4Do you know what the recommendation is for physical activity and sedentary behavior to health?We know that there are many determinants and barriers to physical activity. Among them are the extrinsic factors such as environmental, socioeconomics, and sociopolitical as intrinsic motivation, self-perception, self-efficacy and level of knowledge.
My questions are: Are people becoming inactive due to lack of knowledge of practical recommendations for physical activity, as well as the volume and intensity to achieve health benefits? Would an intervention program based on the recommendations of health would increase levels of physical activity?
Inactivity and sedentary behaviour are totally different constructs. One (Inactivity) is the failure to be physically active and the prevailing behavioural literature suggests that this has more to do with intention - ie. if your intend to be active, this is is usually a strong motivator to do that behaviour. You can read up more on the theories articulating this Transtheoretical model and the Social Cognitive Theory.
Sedentary behaviour, it has been argued, relies more on habit than intention and has different behavioural constructs - as such, needs to be targeted differently in terms of interventions.
A great discussion paper summarizing the different between the two and the theories that define them is by Dr. Stuart Biddle: http://sporttudomany.hu/Hirlevel/pdf/10/Fit_or_Sit.pdfFollowing
- M. Ricky Ramadhian added an answer:17Can we use mean+/-standard error instead of mean+/-standard deviation when data is non-parametric?I measured cytokines through ELISA in humans, but my values were very skewed since I got huge standard deviation which was nearly 2 fold larger than my mean value.
Shall I use mean+/-standard error instead of mean+/-standard deviation when data is non-parametric?
how about this data if we have data like this?Following
- Greger Lindberg added an answer:36What impact will labeling obesity as a disease have on primary prevention of childhood obesity?The American Medical Association has now joined other organizations in deeming obesity a disease (not just a condition or syndrome). There is hand-wringing about proliferation of pharmaceuticals, surgery, and other medical treatments. What about prevention, and specifically, primary prevention for children? Is there applicable evidence for other diseases to inform us of what to expect for prevention and public health efforts around childhood obesity?
Weight essentially reflects energy intake minus energy expenditure. I think it is wrong to focus on energy intake. We should direct our attention to energy expenditure. A sedentary lifestyle in itself is a strong risk factor for disease and also for obesity. Concentrating on energy intake is rather useless if we do nothing to increase energy expenditure. The latter is probably also much easier to change whereas changing energy intake has at best a short-term but marginal effect on weight.Following
- Masimalai Palaniyandi added an answer:17What is the forward elimination method, SPSS- forward selection or backward elimination?
Data was analysed by SPSS software and the authors mentioned that in the multivariate logistic regression analysis they used forward elimination method
Dear friend Yan Chen,
The both backward and frontward selection or removal methods are used to find the influence of potential confounders (independent variables) and statistical significance on the dependant variables. it is built in or with in Linear Multivariate regression model to see the stepwise regression analysis to see the influence of single variable and multiple variables and also compound variables or factors.
- Javad Amani added an answer:11How we can find the Cut off score of the Scale tool?Suppose I have a Questionnaire for a Stress assessment that contains 30 questions, each question has 5 answers (0- no stress, 1-mild stress, 2- moderate , 3-High stress, 4- Severe stress). The Total score of the 30 question varies from 0 - 120.
How we can categories the Total score (the range of total score is 0-120) into mild , moderate and severe? Which cut off s should l take for mild, moderate and severe?
for likert scale 1 to 2.33 (low), 2.34 to 3.67 (moderate), 3.67 to 5 (high). to do this you should change scoring of your scale from 1 to 5 for each item. then compute the mean of your scale (not sum) and use above method to cut offFollowing
- Ramanathan Krishnan added an answer:99+As a reviewer of a journal, what can/should you do when the author(s) submitted their manuscript simultaneously to two or more journals?Yesterday, I comprehensively reviewed a manuscript for a journal. The review took more than 10 hours of my time and I tried to do my best with more than 43 comments. Unfortunately, today I checked the authors' names and noticed that the manuscript has been recently published (with many faults) in another journal. I am EXTREMELY UPSET that these authors submitted their manuscript simultaneously to (at least) two journals. What did/would you do if you were in my shoes?
This is a difficult situation and the answer is not simple. A s one would qualify this a"much might be siad on bothe sides".
Since I am a retired person I can speak my mind without any bias. young researchers are assessed by their publications, often by numbers and also by the journals. some journals take more than 6 months even to reply. Their problem is that the referees take time, and or proper referee could noe be found easily. whatever it be the young researcher would lose a year before his paper sees the day light. He gets panicky and sends his paper to another journal.. I do not sya that I approve of this tactics but i understand. In my active ays I have ben refereeing papers and i know the difficulty involed. you feel vexed that you consider a paper and unfit but another journal publishe dit. So as some others also have expressed it is all in the game. As long as the paper is a copy or contains incoorect information one could tolerate this. further some jourals ared yong to get papers for their journal and they would gladly publsiha a paper without much caring for the quality. So this situation is not new and it existed 40 years ago too. then the choice was limited but now with mushrroming of categories and journals things get complex.Following
- Sultan Salah added an answer:16What type of statistical analysis should be done in a survey study ?In a survey done in a large population like about 5000 subjects, how to analyze the results statistically ?
Input from the statistician will be of immense help in the conduct of the study and will also help in publication of the study in the reputed journal, nowadays there are various ready made software available in the market . SPSS is widely used in the statistical analysis and accepted by many reputed journals.Following
- Jeffrey E. Jarrett added an answer:23What is the minimum sample size, regardless of total number of population, that can be considered as reliable for performing advanced statistical tests?I have 32 patients with tuberculous meningitis, if I determined the sensitivity and specificity of cerebrospinal fluid adenosine deaminase and I got significant results, does it mean the result can be generalized? Can I determine the predictors of mortality from this sample?
Minimum or optimum sample size is related to your risk of incurring Type ! and Type 2 errors, the assumed standard deviation of the population and the tolerance level. Read a book of statistics of sampling and you will never ask this question again. The issue was solved many years ago.Following
- Muhammad Javed added an answer:13What is being done in your country with the current increase in dengue infection?In my country, dengue cases have increased from around 18000+ in 2012, to 28000+ this year. Deaths due to this viral disease has also increased from 21 to more than 60 this year. How about in your country?
Provincial Governments are actively in mass education of community by media and on improvement of personal health due to this companion, and effective fumigation has resulted in decline of dengue fever this yearFollowing
- Sally Hodges added an answer:5Are there softwares to manage clinical data?I would like to have a software to manage large amounts of clinical data.Following
- Kuldeep Dhama added an answer:33Do Religion and Prayer Benefit Health?I need evidence-based medicine or research to back up these statements if someone can cite where the evidence can be found it will be very helpful and greatly appreciated.
Religion and prayers are believed by many and most population of world, accepted by majority, and many beliefs and examples certify their beneficial effects on well being and healthFollowing
- Amarnath Trivedi added an answer:8Can anyone suggest a topic on mental illness among the elderly for my Pg thesis?I have a plan to do thesis for my public health master's degree on dementia among elderly people in South India. Please suggest a topic which is of public health importance.
thank you for the suggestionsFollowing
- Annette Anderson added an answer:1Has anyone seen additional cases of invasive Neisseria macacae disease in humans?We treated a child with Neisseria macacae bacteraemia. In the literature I can not find any other published cases. Does anyone recall - from their own clinical practice - similar cases?
Dear Dr. Schouten; we might have found N. macacae in an oral sample from a Sudanese study participant. But it has only been identified by 16S rDNA sequencing and the 16S sequences of N. macacae, N. mucosa and N. sicca seem very related. The test person was healthy, so the only conclusion you might draw from this is, that N. macacae might have been part of his oral microbial flora.
- Elena Kulikalova added an answer:5What are your reservations with using GIS for health purposes?As it turns, GIS is fast gaining ground with more applications every year. The GIS-health nexus has always been a special one, especially with regard to communicable diseases. As technology drives many facets of health care and research, is the use of GIS still lagging behind? I aim to understand why!
GIS is used not still enough and cause of it is a technical complexity of the product, and lack of IT competence in medical researchers knowledge (there is no information how to use GIS). I think, GIS is not only visualization tool, but also is a possibility for analysis like spatial-temporal spreading and density occurrence of infection disease etc. Researcher can try to use soft EpiInfo 7.0 of Centers for Disease Control and Prevention.Following
About Epidemiology and Public Health
Identifying patterns of health and disease among populations.