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Question:1 Regarding fixed air-flow obstruction in ASTHMA, how do you clinically describe this air-flow limitation?Fixed airflow obstruction is a clinical subtype or phenotype of Difficult-to-treat Asthma. Is there any specific spirometry criteria on which we can ... [more]
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Question:6 Why doesn't the chronic HDM mouse model for allergic airway disease need inhalation provocation like the OVA mouse model?Can anyone tell me why the chronic HDM mouse model for allergic airway disease (HDM exposure intranasal 5 days/week, for 5 or 7 weeks) doesn’t need ... [more]
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Question:6 Leukotriene-receptor antagonists are used in asthma patients. How often did you encounter extreme nervousness and nightmares in LTRA-treated patients?Safety issues are of major concern, especially in asthmatic children. Parental concern was, untill recently, dominated by corticophobia. Recent data i... [more]
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Question:Open Has anyone used the Newcastle asthma knowledge questionnaire? I need to get my hands on it but have had no joy from the team who devised it.I have devised an e-learning package and want to do pre/post test analysis of knowledge.
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Question:2 Asthma in childhood and resisted exercises: what is known about this?Resistance training in childhood has been questioned, but today we know the great potential of this kind of anti inflammatory activity. The AAP does n... [more]
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Question:8 Which cells are more important in chronic lung fibrosis? Fibroblasts, fibrocytes, myofibrocytes. What about chronic inflammation?Chronic lung diseases are complicated. In most of the chronic cases, tissue remodeling is observed. Inflammation and fibrosis are two arms of this phe... [more]
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Question:Open Do microbes change their environment of the nasal passageway in people with asthma?The nose is one of the few openings through which microbes have direct access to get inside the body. The nasal passage is important for filtering the... [more]
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Question:7 Can a patient with asthma and hypothyroidism undergo orthodontic treatment?-
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Question:1 Biomarkers in childhood asthma : Is urine or sputum a better source?Http://www.acceleratingscience.com/1784878/biomarkers-in-asthma-improving-diagnosis-in-early-childhood/
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Question:Open Any danger from long term or very long term usage of salbutamol inhalers for asthma/bronchitis?Any danger from long term or very long term usage of salbutamol inhalers for asthma/bronchitis?
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Question:3 What is the best respiratory scoring system for inpatients and ED?asthma, COPD, viral illness, unspecified wheezing
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Question:Open What's a good example of a matched case-control study for ER and Hospitalization outcomes subsequent to an asthma control intervention?Merging data on the intervention group with Medicaid claims data to obtain control cases and outcome measures.
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Question:8 What factors effect oxidative stress in diseases?I have studied a lot about oxidative stress in COPD and asthma and have heard a bit about its induction during environmental factors. For e.g. the hea... [more]
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Question:5 Comet assay on asthma patientsWe are planning to study the extent of DNA damage in Asthma patients using the biomarkers viz. Comet assay (SCGE) and Micronucleus assay. I would like... [more]
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Question:2 Work-related asthma in woodworkersWhat are the risk factors?
About Asthma
A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).