Monika Garg

Publications (7)13.71 Total impact

• Article: Primary papillary adenocarcinoma of the fallopian tube with ovarian metastasis.

  Nisha Marwah, Monika Garg, Shilpa Garg, Divya Sethi
  Journal of laboratory physicians 01/2012; 4(1):62-3.
• Article: Pleomorphic adenoma of the upper lip.

  Sant Parkash Kataria, Parul Tanwar, Divya Sethi, Monika Garg
  Journal of Cutaneous and Aesthetic Surgery 09/2011; 4(3):217-9.
• Article: Intramuscular lipoma of tongue.

  Monika Garg, Ruchika Aggarwal, Divya Sethi, Deepti Gupta, Rajeev Sen
  Journal of Cutaneous and Aesthetic Surgery 05/2011; 4(2):152-3.
• Article: Brain abscesses: etiologic categorization with in vivo proton MR spectroscopy.

  Monika Garg, Rakesh K Gupta, Mazhar Husain, Sanjeev Chawla, Jayant Chawla, Rajesh Kumar, Sajja B Rao, Mithlesh K Misra, Kashi N Prasad
  [show abstract] [hide abstract]
  ABSTRACT: To compare the metabolite patterns observed at in vivo proton magnetic resonance (MR) spectroscopy of brain abscesses in patients for whom bacteriologic information was obtained from cultures and to categorize the MR spectral patterns with respect to the underlying etiologic agents. MR imaging and in vivo single-voxel proton MR spectroscopic data obtained from 75 patients with brain abscesses were retrospectively analyzed. Ex vivo spectroscopic experiments with the pus from 45 of these patients also were performed, and the data were further categorized on the basis of bacteriologic information. Quantification of various metabolites and metabolite ratios and statistical analyses of lactate and lactate/amino acid (AA) ratio levels were performed by using one-way analysis of variance. On the basis of in vivo proton MR spectroscopic and bacteriologic analysis findings, data were classified into three categories: Group 1 data showed resonances of lactate, AAs, and acetate, with or without succinate at proton MR spectroscopy; cultures for this group showed obligate anaerobes or a mixture of obligate and facultative anaerobes. The metabolite patterns in the group 2 and group 3 data were similar to the pattern of the group 1 data, with the exception that acetate and succinate resonances were absent. Culture was positive for either obligate aerobes or facultative anaerobes in group 2 and was sterile in group 3. At analysis of variance, in vivo data showed significant differences in lactate/AA ratios (P =.008), and ex vivo data showed significant differences in lactate levels (P =.001) among the three groups. It is possible to differentiate anaerobic from aerobic or sterile brain abscesses on the basis of metabolite patterns observed at in vivo proton MR spectroscopy. This information may be useful in facilitating prompt and appropriate treatment of patients with these abscesses.
  Radiology 03/2004; 230(2):519-27. · 5.73 Impact Factor
• Article: Prediction of viability of porcine neurocysticercosis with proton magnetic resonance spectroscopy: correlation with histopathology.

  Sanjeev Chawla, Rakesh K Gupta, Nuzhat Husain, Monika Garg, Rajesh Kumar, Sunil Kumar
  [show abstract] [hide abstract]
  ABSTRACT: Neurocysticercosis (NCC) is the most frequent parasitic disease of central nervous system. In our earlier study, we had observed creatine [(creatine + phosphocreatine); (tCr)] on ex vivo proton MR spectroscopy (1H MRS) in some of the cysticercus cyst fluid samples obtained from swine's brain parenchyma. In current study, swine brains of freshly slaughtered animals naturally infected with NCC were subjected to ex vivo magnetic resonance (MR) imaging on a 1.5Tesla MR system. Cysticercus cysts (n = 12) were removed from these brains and were labeled depending upon presence or absence of edema around cysts as observed on imaging. Cysticercus cyst fluid (100 microl) was subjected to different 1H MRS experiments and results were compared with histopathological examinations to look for any relationship between tCr and parameters like quantification of musculature, and cellular infiltration in wall of the parasite. Histopathology of cyst wall was categorized into two groups based on cellular characteristics and the amount of musculature. Grade I cysts (n = 5) with no or minimal inflammation and large amount of musculature showed tCr on 1H MRS. However, grade II cysts (n = 7) with profuse inflammation and less amount of musculature in the cyst wall lacked tCr. Higher amount of musculature in grade I cysts was associated with higher concentration of tCr in the cyst fluid (r2 = 0.93, P = 0.007). Creatine appears to be a marker of innocuous and viable NCC.
  Life Sciences 02/2004; 74(9):1081-92. · 2.53 Impact Factor
• Article: Differentiation of hydatid cyst from cysticercus cyst by proton MR spectroscopy.

  Monika Garg, Sanjeev Chawla, Kashi N Prasad, Raja Roy, Sadiq S Sikora, Rajesh Kumar, Mazhar Husain, C L Khetrapal, Rakesh K Gupta
  [show abstract] [hide abstract]
  ABSTRACT: The metabolite patterns obtained by ex vivo proton MR spectroscopy of fluid from different locations of hydatid cysts of sheep and humans (n = 16) and cysticercus cysts of swine and humans (n = 25) were compared with an objective of differentiating the two parasites on the basis of their metabolite pattern. The spectra from hydatid fluid differed from cysticercus cyst by the absence of creatine in the former. When the hydatid cyst was fertile, malate and/or fumarate was also observed, which was absent in cysticercus cyst. The most likely explanation for the presence of creatine only in the cysticercus fluid is its active diffusion from the surrounding host tissue along with a contribution from the musculature present in the bladder wall of the cyst.
  NMR in Biomedicine 09/2002; 15(5):320-6. · 3.21 Impact Factor
• Article: Fertility assessment of hydatid cyst by proton MR spectroscopy.

  Monika Garg, Rakesh K Gupta, Kashi N Prasad, Sadiq S Sikora, Lily Pal, Sanjeev Chawla, Rajesh Kumar, Mazhar Husain, Sudhir Saxena, Nuzhat Husain, Raja Roy
  [show abstract] [hide abstract]
  ABSTRACT: Hydatid cysts, the larvae of the parasite Echinococcus granulosus, may lodge in any organ of intermediate hosts, namely, man and sheep. Complete cyst removal is the treatment of choice; however, spillage of fertile cysts during surgery leads to disease recurrence that may be prevented by preoperative detection of the fertility status of the cyst. With this perspective, ex vivo proton (1H) MR spectroscopy of hydatid fluid of human and sheep origin was performed to differentiate fertile from sterile cysts on the basis of their metabolite pattern. Cysts of sheep and human origin were used as source of hydatid fluid. A fraction of this fluid was tested for cyst fertility and the rest was used for ex vivo1H spectroscopy. Histopathology of the cyst wall was done as a gold standard for this study. Of 10 sheep samples, 7 were fertile and 3 were sterile, while among 6 human samples, 5 were fertile and 1 was sterile. Spectroscopic and histopathological results corroborated each other. The fluid from microbiologically proven fertile cysts contained malate and fumarate along with other resonances and the histopathology of the fertile cyst wall demonstrated germinal lining and protoscoleces. The ex vivo spectroscopic differentiation of fertile and sterile cysts may be a stepping-stone for their in vivo separation in future and thus help in framing strategies for percutaneous/surgical management.
  Journal of Surgical Research 08/2002; 106(1):196-201. · 2.25 Impact Factor