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ABSTRACT: Burn, a person may face, is one of the statuses, which can be a most severe physical and psychologic trauma. Patients with burns commonly have severe itching and pain. Severe itching has also been associated with the anxiety, sleep disturbance, and disruption of daily living activities. The addition of complementary treatments to standard care may lead to a greater pain management and may offer a safer approach for reducing pain and procedural anxiety for patients with burns. The authors conducted an experimental study to examine whether the effects of massage therapy reduced burned adolescents' pain, itching, and anxiety levels. Sixty-three adolescents were enrolled in this study shortly after admission (mean days = 3 +/- 0.48) at a burn unit in a large university hospital from February 2008 to June 2009. The measures including the pain, itching, and state anxiety were collected on the first and last days of the 5-week study period. The participants had an average age of 14.07 +/- 1.78 years and came usually from the lower socioeconomic strata. The authors observed that massage therapy reduced all these measures from the first to the last day of this study (P < .001). In most cultures, massage treatment are used to alleviate a wide range of symptoms. Although health professionals agree on the use of nonpharmacologic method for patients with burns, these applications are not yet common.
Journal of burn care & research: official publication of the American Burn Association 03/2010; · 1.37 Impact Factor
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ABSTRACT: Tandir is the name given to an oven used for baking bread in the eastern and south-eastern part of Anatolia. Tandir burn is a special kind of burns in which primarily women and small children fall in it and have deep extensive burns (TBSA %). The records of 60 patients with tandir burn who were treated in our Burn Center from September 1999 to January 2006 were reviewed. The patients consisted of 9.2% of all burned patients. The mean age was 17.10 years (1-60 years) and 61.50% of the patients were female. The mean total body surface area (TBSA) burned was 21.09% (6-58) and 88% of the patients had third-degree burns. Eight of the patients underwent amputation of an extremity, 10 had fasciotomies, and 25 partial thickness skin grafts. The mean hospitalization period was 31.64 days (3-73 days). Fifteen patients (25%) died. Tandir burn is a severe kind of burn with a higher morbidity and mortality.
Burns 04/2008; 34(2):268-70. · 1.96 Impact Factor
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ABSTRACT: While tuberculosis of the breast is an extremely uncommon entity seen in western populations, it accounts for up to 3% of all treatable breast lesions in developing countries.
We reviewed three female cases of mammary tuberculosis that were diagnosed and treated in Turkey during the same calendar year. All three patients presented with a painful breast mass. In all cases, fine needle aspiration was nondiagnostic for mammary tuberculosis. However, the diagnosis of mammary tuberculosis was confirmed by histopathologic evaluation at the time of open surgical biopsy. All three patients were treated with antituberculous therapy for six months. At the end of the treatment period, each patient appeared to be clinically and radiologically without evidence of residual disease.
The diagnosis of mammary tuberculosis rests on the appropriate clinical suspicion and the histopathologic findings of the breast lesion. Its recognition and differentiation from that of a breast malignancy is absolutely necessary. Antituberculous chemotherapy, initiated immediately upon diagnosis, forms the mainstay of treatment for mammary tuberculosis.
World Journal of Surgical Oncology 02/2007; 5:67. · 1.12 Impact Factor
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Digestive Diseases and Sciences 07/2005; 50(6):1127-9. · 2.12 Impact Factor
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International Journal of Antimicrobial Agents 01/2005; 24(6):624-5. · 4.13 Impact Factor
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ABSTRACT: Adrenal cysts are very rare lesions, especially with parasitic origin. But with the wider application of ultrasonography (US) and computed tomography (CT) more adrenal cysts are detected incidentally. To gain more insight into this entity, the records of nine patients with hydatid cysts of adrenal gland seen at our department from January 1980 till January 2002 are reviewed. There were four men and five women, and their ages ranged from 15 to 80 years (median: 41 years). All of the patients had unilateral cysts. Seven cysts were located on the right and two on the left side. Five of the cysts were primary and four were secondary. In three patients the cysts were found incidentally. The most common presenting symptom was pain, which was present in six patients. An indirect hemagglutination (IHA) test was positive in six cases. In all patients, US and CT successfully imaged all cysts, but the definitive diagnosis was made by macroscopic and microscopic examination of the cyst's content. The patients were treated surgically. In all patients adrenal glands with the cystic masses were removed. The median follow-up period was 16 months (range: 6-64 months). No evidence of recurrence was found in any patient. It should not be forgotten that cystic masses of the upper abdomen might also originate from the adrenal gland. The etiology and nature of the cyst should be well researched, and appropriate treatment should be given as soon as possible. Surgical excision of the gland, including the cyst is the treatment of choice.
World Journal of Surgery 02/2004; 28(1):97-9. · 2.36 Impact Factor
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ABSTRACT: To evaluate the blood levels of lipids, insulin resistance and the release of insulin in the patients with fatty liver.
Ninety one patients with fatty liver and forty seven healthy subjects were included in the study. The diagnosis of fatty liver was established by measuring blood levels of lipids and measuring liver echogenity by ultrasound. Fasting plasma levels of lipids, glucose and insulin were measured in the patient group and control group, and the rate of insulin resistance was calculated. HOMA test was used to calculate the insulin resistance. INSULIN RESISTANCE: Fasting insulin value (microU/mL) x Fasting blood glucose value (mmol/L)/22.5 Liver echogenity was measured by a 3.75 mHz ultrasound probe and was graded by comparison with renal cortical paranchymal echogenity in both groups. Increased blood levels of lipids and increased liver echogenity on the ultrasonography were accepted as fatty liver. Liver biopsy was not applied. The patients with liver and/or renal paranchymal disease were excluded from the study. The rate of release of insulin was calculated according to the following formula. 20 x plasma levels of insulin (mIU/mL)/plasma levels of glucose (mmol/L)-3.5
In the fatty liver group, plasma levels of cholesterol were 253.5 +/- 41.0 (161-440) mg/dL, plasma levels of triglycerides were 231.8 +/- 74.4 (45-493) mg/dL, grading of liver echogenity was 1.9 +/- 0.6 (1-3), the rate of release of insulin was 111.5 +/- 82.2 (3-463.8) and the rate of insulin resistance was 22.4 +/- 4.1 (18.3-26.5). In the control group, plasma levels of cholesterol were 173.4 +/- 19.1 (122-207) mg/dL, plasma levels of triglycerides were 110.5 +/- 39.3 (40-185) mg/dL, grading of liver echogenity was 1.0 +/- 0.1 (1-1), the rate of release of insulin was 129.6 +/- 84.1 (14.5-360) and the rate of insulin resistance was 20.3 +/- 2.1 (18.2-22.4). The rate of release of insulin and insulin resistance were similar in both groups (p>0.5).
We observed that the rate of release of insulin in the patients with fatty liver was not different from that of the healthy subjects.
Hepato-gastroenterology 01/2004; 50 Suppl 2:cclxxvi-cclxxviii. · 0.66 Impact Factor
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ABSTRACT: The effects of intranasal calcitonin on bone metabolism were investigated in patients with hyperthyroidism. Urinary deoxypyridinoline (uDPD) levels were measured as a bone turnover marker and lumbar spine (L2) bone mineral density (BMD) was measured by dual-energy X-ray absorptiometry (DEXA) in 7 patients who were given only antithyroid drug (group 1), in 10 patients who were given antithyroid drug plus intranasal calcitonin (group 2), and in 10 healthy subjects who were given placebo (group 3) at the beginning and at the end of the study. The study continued until the patients with hyperthyroidism became euthyroidic according to the laboratory values. This period was approximately 3 months in groups 1 and 2. At the beginning of the study, uDPD was 21.5 +/- 2.6 nM DPD/mM creatinine in group 1, 23.3 +/- 3.6 nM DPD/mM creatinine in group 2, and 4.3 +/- 1.2 nM DPD/mM creatinine in group 3. uDPD levels measured in groups 1 and 2 were significantly higher than those in group 3 ( P < 0.001). Area BMD Z scores of the patients in groups 1 and 2 were significantly lower than the healthy controls ( P < 0.01, for both). At the end of the study, uDPD was 11.5 +/- 1.6 nM DPD/mM creatinine in group 1, 5.3 +/- 0.6 nM DPD/mM creatinine in group 2, and 4.4 +/- 1.3 nM DPD/mM creatinine in group 3. The levels of uDPD obtained in group 1 were significantly higher than those obtained in groups 2 and 3 ( P < 0.05, for both). The difference between groups 2 and 3 was not significant. Area BMD Z scores measured at the end of the study were found to be increased in groups 1 and 2 compared to early values, but the values were slightly lower than the normal values. In comparison of early and late uDPD values, the decrease in late period was statistically significant in groups 1 ( P < 0.05) and 2 ( P < 0.001). We concluded that bone turnover is high in hyperthyroidism. The treatment of hyperthyroidism decreases the rate of bone turnover, but it is not sufficient to prevent the degradation of bone in hyperthyroidism. The addition of intranasal calcitonin to the treatment of hyperthyroidism prevents the degradation of bone.
Journal of Bone and Mineral Metabolism 01/2004; 22(2):90-3. · 2.27 Impact Factor
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ABSTRACT: To investigate the presence of the antigliadin antibodies in the patients with Graves' disease and Hashimoto's thyroiditis.
Four hundred patients with autoimmune thyroid disease (280 Graves' disease and 120 Hashimoto's thyroiditis ) were included in the study. The patients with celiac sprue patients were excluded. For the diagnosis of autoimmune thyroiditis, blood levels of thyrotropin (TSH), free thyroxine (FT4), and the titration of thyroid autoantibodies (TgAb and TmAb) were measured, and the thyroid gland was ultrasonographycally evaluated. After the diagnosis of autoimmune thyroid disease was established, the titration of antigliadin antibodies (Ig A and B) were routinely detected.
Twenty two patients (5.5 per cent) with autoimmune thyroiditis had positive antigliadin antibodies. Polyglandular endocrine syndrome was diagnosed in most of these patients.
We claim that polyglandular endocrine syndrome is the commonest cause of positivity of antigliadin antibodies in the patients with autoimmune thyroid disease.
Hepato-gastroenterology 01/2004; 50 Suppl 2:cclxxix-cclxxx. · 0.66 Impact Factor
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ABSTRACT: To investigate the liver function tests during antithyroid treatment in the patients with hyperthyroidism.
Four hundred sixty five patients with hyperthyroidism (285 Graves' disease and 180 toxic nodular/multinodular goiter) and fifty healthy subjects were included in the study. The patients who had abnormal liver function tests were excluded from the study. Blood levels of thyrotropin (TSH), free thyroxine (FT4), alanine transaminase (ALT) and aspartate transaminase (AST) were detected at the beginning of the treatment (basal levels), and at the third and sixth months of the treatment. The patients were treated with propylthiouracil (PTU).
Average of age was 40.1 +/- 5.8 years in the patient group and was 37.3 +/- 4.5 years in the control group. TSH, FT4, ALT and AST levels measured in the patient and control group are shown in Table 1. Basal levels of TSH were lower in the study group than in the control group (p<0.001), and basal levels of FT4 were higher in the study group than in the control group (p<0.001). Basal levels of ALT and AST, and the levels of TSH, FT4, ALT and AST measured at the third and sixth months were similar in both groups.
We did not find abnormal liver function tests during the antithyroid treatment in the patients with hyperthyroidism.
Hepato-gastroenterology 01/2004; 50 Suppl 2:cclxxxi-cclxxxii. · 0.66 Impact Factor
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ABSTRACT: Hospital-acquired infections are the ones that develop within hospital stay or appear after discharge. These infections are associated with an increased rate of morbidity and mortality, longer hospital stay and higher hospital costs and Hospital Infections Control Committees have been founded to prevent it. In this review, we intended to investigate the role of the surgeon in this committee.
Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery: TJTES 10/2003; 9(4):225-31. · 0.33 Impact Factor
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ABSTRACT: Reduced bone formation and bone loss have been documented in patients following burn injury. Urinary deoxypyridinoline (DPD) is accepted as a marker of collagen breakdown activity. Because calcitonin (CT) diminishes bone resorption and growth hormone (GH) increases bone formation and density in GH-deficient patients, we studied the short-term effects of CT and GH on urinary DPD levels in burned patients. In 30 patients with severe burns, urinary DPD levels were investigated for 3 days following hospitalisation. Then the patients were divided into 3 groups of 10. In the CT group, CT 100U was injected subcutaneously daily for 5 days. In the GH group, GH 0.1mg/kg was injected subcutaneously three times in a week. In the control group, isotonic saline solution 0.1mg/kg was injected subcutaneously three times in a week. In all groups, following the last dose of the agents, urinary DPD levels were investigated for 3 days again. Mean burn size and age were not significantly different between the groups. Urinary DPD level obtained in the early period was 16.5 +/- 3.1nM in the CT group, 10.4 +/- 5.3nM in the GH group and 18.6 +/- 2.7nM in the control group. There were no statistical differences among the groups (P > 0.5, for all). Urinary DPD level obtained in the late period was 4.5 +/- 1.0nM in the CT group, 14.4 +/- 5.9nM in the GH group and 36.6 +/- 2.1nM in the control group. The differences between the CT group and control group, the CT group and GH group and the GH group and control group were statistically significant (P < 0.001, P < 0.01, P < 0.01, respectively). In the comparison of early and late urinary DPD levels, a significant decrease was only obtained in the CT group (P < 0.001, Z:6.5). In the other 2 groups, DPD levels increased in the late period. We concluded that GH is not effective in decreasing urinary DPD levels. On the contrary, CT was found to very effective in decreasing urinary DPD levels. This decrease in urinary DPD levels may be associated with diminished bone loss
Burns 06/2002; 28(4):311-3. · 1.96 Impact Factor
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ABSTRACT: Burn can be among the most severe physical and psychologic traumas a person may face. Patients with burns commonly have severe itching and pain. Severe itching has also been associated with anxiety, sleep disturbance, and disruption of daily living activities. The addition of complementary treatments to standard care may lead to improved pain management and may offer a safer approach for reducing pain and procedural anxiety for patients with burns. The authors conducted an experimental study to examine whether the effects of massage therapy reduced burned adolescents' pain, itching, and anxiety levels. Sixty-three adolescents were enrolled in this study shortly after admission (mean days = 3 +/- 0.48) at a burn unit in a large university hospital from February 2008 to June 2009. The measures including the pain, itching, and state anxiety were collected on the first and last days of the 5-week study period. The participants had an average age of 14.07 +/- 1.78 years and came usually from the lower socioeconomic strata. The authors observed that massage therapy reduced all these measures from the first to the last day of this study (P < .001). In most cultures, massage treatments are used to alleviate a wide range of symptoms. Although health professionals agree on the use of nonpharmacologic method for patients with burns, these applications are not yet common.
Journal of burn care & research: official publication of the American Burn Association 31(3):429-32. · 1.37 Impact Factor
