[Show abstract][Hide abstract] ABSTRACT: Case 1 involved a 51-year-old man who underwent appendectomy with a diagnosis of acute appendicitis. The postoperative histological diagnosis was goblet cell carcinoid (GCC). Laparoscopic ileocecal excision was performed. Case 2 involved a 43-year-old woman who underwent simple abdominal hysterectomy + bilateral salpingo-oophorectomy with a suspicion of bilateral malignant ovarian tumors. During the operation, a swollen appendix was detected and it was simultaneously resected. The postoperative histological diagnosis was GCC of the appendix and ovarian metastasis. Right hemicolectomy was performed. Case 3 involved a 73-year-old man who underwent appendectomy with a diagnosis of acute appendicitis. The postoperative histological diagnosis was GCC. An abdominal CT scan undertaken after the operation revealed a nodular lesion which had oppressed the rectum. Accordingly ileocecal excision + Hartmann operation were performed.GCC is classified into a subtype of adenocarcinoma and has a high grade of malignant potential. The preoperative diagnosis is difficult and we have to consider some additional therapy. As we recently experienced three cases of GCC diagnosed after appendectomy and performed reoperation, these cases are presented here with a review of the literature.
Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 01/2014; 75(7):1909-1914. DOI:10.3919/jjsa.75.1909
[Show abstract][Hide abstract] ABSTRACT: We have encountered a case of malignant lymphoma of the stomach in which a complete remission was confirmed in a resected specimen after chemotherapy. A 75-year-old woman complained of vomiting blood. A biopsy from gastric endoscopy indicated malignant lymphoma of diffuse large B-cell type. The patient was assumed to be inoperable due to enlargement of the tumor and lymph node metastasis, and THP-COP chemotherapy was carried out. After four courses of the THP-COP regimen, endoscopic examination revealed a significant tumor reduction. Total gastrectomy and splenectomy with lymph node dissection (D2) were performed after chemotherapy. No tumor cells were detected in any sections of the specimen or regional lymph nodes.
Gan to kagaku ryoho. Cancer & chemotherapy 07/2002; 29(6):943-7.
[Show abstract][Hide abstract] ABSTRACT: A 52-year-old woman complaining of breast tumor was diagnosed as having advanced breast cancer (T4bN1M1-Stage IV), with metastasis of multiple organs (lung, liver, mediastinal and unilateral axillary lymph nodes) after which she underwent tumorectomy. Postoperative adjuvant therapy was performed using combined chemoendocrine therapy (CAF + 5'-DFUR + MPA). Following the endocrine therapy, the metastatic lesions of the liver and lung had disappeared. The adverse effects were not remarkable. Complete remission was continued for 2 years and 3 months, and the patient enjoyed a favorable quality of life.
Gan to kagaku ryoho. Cancer & chemotherapy 01/2001; 27(14):2235-8.