K C Allman

Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia

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Publications (78)364.23 Total impact

  • Seung Wook Ryu, Kevin C Allman
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    ABSTRACT: The value of (99m)Tc-labeled white blood cell scintigraphy for endovascular prosthetic infections is well known. In the unique case reported here, infection of the native aorta was detected in addition to an infected vascular prosthesis. The case demonstrates that (99m)Tc-labeled white blood cell scintigraphy can identify not only the more usual prosthetic stent/graft infection but also infection of the native aorta. When scrutinizing studies for infection of prosthetic material, readers should also carefully examine the native aorta.
    Journal of Nuclear Medicine Technology 02/2014;
  • Seung Wook Ryu, Adrian Waugh, Kevin C Allman
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    ABSTRACT: Extrapulmonary deposition of macroaggregated albumin particles on lung perfusion scintigraphy occurs in the presence of right-to-left shunting, as demonstrated in this case of portosystemic shunting related to superior vena cava obstruction by germ cell tumor of the mediastinum. The case demonstrates the importance of examining tracer deposition within the entire field of view on (99m)Tc-macroaggregated albumin perfusion lung scintigraphy for extrapulmonary findings.
    Journal of Nuclear Medicine Technology 02/2014;
  • Kevin C Allman
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    ABSTRACT: Observations of reversibility of cardiac contractile dysfunction in patients with coronary artery disease and ischemia were first made more than 40 years ago. Since that time a wealth of basic science and clinical data has been gathered exploring the mechanisms of this phenomenon of myocardial viability and relevance to clinical care of patients. Advances in cardiac imaging techniques have contributed greatly to knowledge in the area, first with thallium-201 imaging, then later with Tc-99m-based tracers for SPECT imaging and metabolic tracers used in conjunction with positron emission tomography (PET), most commonly F-18 FDG in conjunction with blood flow imaging with N-13 ammonia or Rb-82 Cl. In parallel, stress echocardiography has made great progress also. Over time observational studies in patients using these techniques accumulated and were later summarized in several meta-analyses. More recently, cardiac magnetic resonance imaging (CMR) has contributed further information in combination with either late gadolinium enhancement imaging or dobutamine stress. This review discusses the tracer and CMR imaging techniques, the pooled observational data, the results of clinical trials, and ongoing investigation in the field. It also examines some of the current challenges and issues for researchers and explores the emerging potential of combined PET/CMR imaging for myocardial viability.
    Journal of Nuclear Cardiology 06/2013; · 2.85 Impact Factor
  • Bjoern Kitzing, Paul J Torzillo, Kevin C Allman
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    ABSTRACT: We present the right to left shunt study findings of a 50-year-old male patient with hepatitis C cirrhosis, who complained of worsening dyspnea on exertion. Follow-up images showed resolution of hepatopulmonary syndrome following methadone withdrawal although there had been no improvement in his liver disease. This was unusual and may have been due to the effect of opiate receptors on nitric oxide signaling in the pulmonary vasculature.
    Clinical nuclear medicine 02/2011; 36(2):152-3. · 3.92 Impact Factor
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    Bjoern Kitzing, Kevin C Allman
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    ABSTRACT: To the best of our knowledge, we present for the first time the bone scintigraphy findings of a patient with Morquio's syndrome. A 46-year-old Caucasian man with Morquio's syndrome presented with lower back pain six weeks after a left total hip replacement. A whole body bone scan demonstrated an anthropomorphic skeletal pattern consistent with a mucopolysaccharide storage disease, thereby showing the cause of the patient's pain. To the best of our knowledge, the bone scintigraphy findings of a case of Morquio's syndrome have never before been published. We present our case report to add to the knowledge we have of this rare disease.
    Journal of Medical Case Reports 01/2011; 5:42.
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    Journal of Nuclear Cardiology 08/2010; 17(4):709-18. · 2.85 Impact Factor
  • Kevin C Allman
    Journal of Nuclear Medicine 03/2010; 51(4):505-6. · 5.77 Impact Factor
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    ABSTRACT: Polyarteritis nodosa can on rare occasions manifest itself as vasculitis of the gallbladder. Patients typically present with right upper quadrant pain and are initially worked up for cholecystitis. The definitive diagnosis is then usually based on surgical and histopathological findings. In this case a 23-year-old Caucasian female presented with a 3 week history of right upper quadrant pain and fevers. The clinical pathway and imaging findings of a rare case of gallbladder vasculitis as a manifestation of polyarteritis nodosa are demonstrated.
    Cases Journal 01/2009; 2:9300.
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    ABSTRACT: Controversy exists regarding the safety of intravenous dipyridamole in patients with severe chronic obstructive pulmonary disease (COPD), and it is contraindicated in patients with asthma. There is currently little published literature on the safety of adenosine in patients with airways disease, despite potential advantages over dipyridamole with respect to side effects. We studied 46 consecutive patients with a history of COPD or asthma undergoing adenosine stress myocardial perfusion scintigraphy. Spirometry with measurement of forced expiratory volume in 1 s (FEV(1)), forced vital capacity, peak expiratory flow rate and a repeat FEV(1) postinhaled bronchodilator in all those with a history of asthma was performed prior to receiving intravenous adenosine 140 mg/kg/min for 4 min. The cohort exhibited significant airflow limitation on spirometry (see Table 1), however the majority of patients (24/46) did not experience any dyspnoea or chest pain during adenosine infusion. Fourteen patients experienced chest discomfort during adenosine, and 9 complained of dyspnoea. No patient required aminophylline or resuscitative measures. In our cohort of patients with a history of COPD, asthma or both who demonstrated impaired lung function on spirometry, adenosine was safe and well tolerated.
    International journal of cardiology 08/2007; 128(3):436-8. · 6.18 Impact Factor
  • Journal of Nuclear Cardiology 07/2006; 13(4):S5. · 2.85 Impact Factor
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    ABSTRACT: Acute pulmonary thromboembolism (PTE) can be associated with right ventricular (RV) dysfunction. The relative importance of individual echocardiographic parameters, including those suggesting interdependence between right and left heart chambers, in predicting thromboembolic burden in elderly patients with acute PTE is unknown. We retrospectively studied the transthoracic echocardiograms of 63 elderly patients (age 71 +/- 16 years) with acute PTE, and assessed which individual echocardiographic parameters identified more than 30% pulmonary artery obstruction on the basis of quantitative ventilation/perfusion pulmonary scintigraphy. RV hypokinesis (visual grade 0-3, P = .02), and the quantitative parameters RV end-systolic area (P = .005) and RV ejection area (P = .01) were associated with more extensive pulmonary artery obstruction. Although right atrial end-systolic area and RV end-diastolic area did not correlate with extent of PTE, the ratio of RV:left ventricular end-diastolic area (P = .003), and ratio of right:left atrial end-systolic area (P = .004), were strongly associated with the extent of pulmonary artery obstruction. These transthoracic echocardiographic parameters were independent of clinical variables such as prior chronic lung disease, congestive cardiac failure, or prior PTE. RV systolic dysfunction, RV end-systolic dilatation, right:left atrial end-systolic area ratio, and RV:left ventricular end-diastolic area ratio correlate with extent of PTE in the elderly.
    Journal of the American Society of Echocardiography: official publication of the American Society of Echocardiography 04/2006; 19(3):347-53. · 2.98 Impact Factor
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    ABSTRACT: Transient ischemic dilation of the left ventricle found on SPECT myocardial perfusion imaging (MPI) is an accepted marker of severe and extensive coronary artery disease (CAD) and poor prognosis. The influence of other clinical variables on the incidence of transient ischemic dilation is less certain. The aim of this study was to investigate clinical factors that may influence the incidence of transient ischemic dilation. In particular, we looked at factors that may independently affect subendocardial perfusion, such as left ventricular hypertrophy (LVH) and diabetes. MPI studies of 103 consecutive patients who had undergone recent coronary angiography (< or =6 mo) and transthoracic echocardiography within a year of stress electrocardiography-gated MPI were retrospectively analyzed. Transient ischemic dilation was assessed quantitatively using a software program. A ratio cutoff of > or =1.22 was considered to represent transient ischemic dilation. Summed stress score and summed difference score (ischemia score) were determined using the standard 17-segment 5-point scoring system to quantify myocardial ischemia. LVH was defined as a left ventricular wall thickness of >11 mm on M-mode echocardiography. Severe CAD was defined as severe stenosis (> or =90%) of either the left anterior descending artery or both the right coronary and lateral circumflex arteries. Nineteen (18%) of the 103 patients had transient ischemic dilation, 19 (18%) had LVH, and 23 (22%) were diabetic. A high percentage had severe CAD (46/103 [45%]), whereas 57 of 103 (55%) had less severe CAD (30/103 [29%]) or nonsignificant CAD (26/103 [25%]). Severe CAD (P < 0.001), diabetes (P < 0.0001), LVH (P < 0.003), and the ischemia score (P < 0.023) were independent predictors of transient ischemic dilation by multivariate logistic regression. In patients with severe CAD, the effect of LVH on the incidence of transient ischemic dilation was additive, increasing the incidence from 21% (8/38) without LVH to 75% (6/8) with LVH (P < 0.006). Likewise, with severe CAD, the incidence of transient ischemic dilation rose from 21% (7/33) in patients without diabetes to 54% (7/13) in those with diabetes (P < 0.04). The presence of transient ischemic dilation on myocardial perfusion SPECT is associated with the presence of severe CAD, but this association is modified by the presence of LVH and diabetes.
    Journal of Nuclear Medicine 10/2005; 46(10):1596-601. · 5.77 Impact Factor
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    ABSTRACT: A 26-year-old man presented with left lower leg pain after a skiing injury. Plain radiography was initially reported as normal at the site of the suspected fracture but revised after the bone scan. An additional area of calcification was described adjacent to the proximal fibula without a conclusive diagnosis. A fibula fracture was easily apparent on Tc-99m bone scintigraphy, and the more proximal focus of uptake in the soft tissues was thought to be an area of myositis ossificans, subsequently confirmed on ultrasound. The patient provided a history of trauma to the area 1 year previously. The typical correlative imaging features of confounding myositis ossificans and a stress fracture are outlined.
    Clinical Nuclear Medicine 01/2005; 29(12):813-4. · 2.96 Impact Factor
  • Circulation 06/2004; 109(17):2156. · 15.20 Impact Factor
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    ABSTRACT: Transient ischaemic dilatation (TID) on myocardial perfusion imaging (MPI) is an indicator of severe coronary artery disease (CAD), but its dependence on other clinical variables is less well defined. The aim of this study was to explore the relationship between clinical variables, particularly left ventricular hypertrophy (LVH), diabetes, and TID.Methods: MPI studies of 103 consecutive patients who underwent coronary angiography within 6 months and transthoracic echocardiography within a year of stress ECG-gated MPI were retrospectively analysed. TID was assessed visually with the consensus agreement of 2 readers. Summed stress scores (SSS) were determined using the standard 17 segment module. Severe CAD was defined as >90% LAD stenosis, or > 2 vessels >90% stenosis. LVH was defined as LV wall thickness >1.1mm on echo.Results:*VariableTID positiveTID negativeP valueSevere CAD15/28 (62%)28/75 (35%)
    Journal of Nuclear Cardiology 01/2004; 11(4). · 2.85 Impact Factor
  • Kevin C Allman, S Ben Freedman
    Journal of Nuclear Cardiology 01/2004; 11(1):87-9. · 2.85 Impact Factor
  • Kevin C. Allman, Florence Prigent
    Journal of Nuclear Cardiology 11/2003; 10(6). · 2.85 Impact Factor
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    ABSTRACT: An 85-year-old male resident of a nursing home presented after a fall with a painful left hip, confusion, and fever. He had multiple medical problems including severe vascular disease and poor vision as a result of macular degeneration. An Austin Moore left hip prosthesis had been inserted for a fractured femoral neck several years before. A septic workup showed a raised leukocyte count but no other focal abnormality. Plain radiography showed a periprosthetic fracture of the left hip. Blood cultures grew beta-hemolytic group A Streptococcus sensitive to penicillin. Bone scintigraphy was thought to be consistent with loosening of the prosthesis without evidence of a recent fracture. Tc-99m leukocyte scintigraphy was markedly abnormal, with extensive soft-tissue uptake suggestive of a large periprosthetic infective collection. This was confirmed at surgery with drainage of 200 mL pus from the left hip, and deep and superficial soft tissues of the thigh. The trochanteric fracture was well granulated and thought to be of long standing. The prosthesis was removed and the patient was treated with appropriate antibiotics with good effect.
    Clinical Nuclear Medicine 09/2003; 28(8):694-5. · 2.96 Impact Factor
  • Ernest V. Garcia, Kevin C. Allman, Kevin Allman, John Lekakis, Florence Prigent
    Journal of Nuclear Cardiology 07/2003; 10(4). · 2.85 Impact Factor
  • Hans Van der Wall, Kevin Allman
    European journal of nuclear medicine and molecular imaging 02/2003; 30(1):1-3. · 5.11 Impact Factor

Publication Stats

1k Citations
364.23 Total Impact Points

Institutions

  • 1989–2013
    • Royal Prince Alfred Hospital
      • Department of Pet & Nuclear Medicine
      Camperdown, New South Wales, Australia
  • 2007
    • Oxford University Hospitals NHS Trust
      • Department of Cardiology
      Oxford, ENG, United Kingdom
  • 1996–2006
    • Concord Repatriation General Hospital
      Sydney, New South Wales, Australia
  • 2004
    • University of Sydney
      Sydney, New South Wales, Australia
  • 1997–2004
    • Concord Hospital
      Concord, New Hampshire, United States
  • 1993–1998
    • University of Michigan
      • Department of Internal Medicine
      Ann Arbor, MI, United States
  • 1992–1997
    • Concordia University‚ÄďAnn Arbor
      Ann Arbor, Michigan, United States