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I. F. Zhimulev,
E. S. Belyaeva,
E. N. Andreeva,
N. G. Andreenkova,
V. N. Babenko,
S. N. Belyakin,
L. V. Boldyreva,
I. V. Brusentsova,
S. A. Demakov,
O. V. Demakova, I. A. Zykov,
E. B. Kokoza,
T. D. Kolesnikova,
D. A. Maksimov,
I. V. Makunin,
A. V. Pindyurin,
V. F. Semeshin,
V. A. Khoroshko
[show abstract]
[hide abstract]
ABSTRACT: The modern concept of intercalary heterochromatin as polytene chromosome regions exhibiting a number of specific characteristics
is formulated. DNA constituting these regions is replicated late in the S period; therefore, some strands of polytene chromosomes
are underrepresented; i.e., they are underreplicated. Late-replicating regions account for about 7% of the genome; genes are
located there in clusters of as many as 40. In general, the gene density in the clusters is substantially lower than in the
main part of the genome. Late-replicating regions have an inactivating capacity: genes incorporated into these regions as
parts of transposons are inactivated with a higher probability. These regions contain a specific protein SUUR affecting the
rate of replication completion.
Russian Journal of Genetics 04/2012; 46(10):1240-1242. · 0.43 Impact Factor
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I F Zhimulev,
E S Beliaeva,
E N Andreeva,
N G Andreenkova,
V N Babenko,
S N Beliakin,
L V Boldyreva,
I V Brusentsova,
S A Demakov, I A Zykov,
E B Kokoza,
T D Kolesnikova,
D A Maksimov,
I V Makulin,
A V Pindiurin,
V F Semeshin,
V A Khoroshko
[show abstract]
[hide abstract]
ABSTRACT: The modern concept of intercalary heterochromatin as polytene chromosome regions exhibiting a number of specific characteristics is formulated. DNA constituting these regions is replicated late in the S period; therefore, some strands of polytene chromosomes are underrepresented; i.e., they are underreplicated. Late-replicating regions account for about 7% of the genome; genes are located there in clusters of as many as 40. In general, the gene density in the clusters is substantially lower than in the main part of the genome. Late-replicating regions have an inactivating capacity: genes incorporated into these regions as parts of transposons are inactivated with a higher probability. These regions contain a specific protein SUUR affecting the rate of replication completion.
Genetika 10/2010; 46(10):1405-8. · 0.44 Impact Factor
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[show abstract]
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ABSTRACT: The results of a comparative study of cloned DNA fragments of Drosophila simulans, D. mauritiana, D. teissieri, and D. erecta are presented. The fragments were amplified in PCR with primers specified to the region of D. melanogaster interband 61C7/C8. The uniqueness of all cloned fragments in the genomes of these species was confirmed. A comparative analysis of nucleotide sequences revealed that the rate of evolution of DNA from D. melanogaster interband 61C7/C8 is close to the rate of neutral evolution in the genus Drosophila.
Genetika 05/2002; 38(4):473-82. · 0.44 Impact Factor
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[show abstract]
[hide abstract]
ABSTRACT: The results of a comparative study of cloned DNA fragments ofDrosophila
simulans, D. mauritiana, D. teissieri, and D. erecta are presented. The fragments were amplified in PCR with primers specified to the region of D. melanogaster interband 61C7/C8. The uniqueness of all cloned fragments in the genomes of these species was confirmed. A comparative analysis of nucleotide sequences revealed that the rate of evolution of DNA from D. melanogaster interband 61C7/C8 is close to the rate of neutral evolution in the genusDrosophila.
Russian Journal of Genetics 03/2002; 38(4):377-385. · 0.43 Impact Factor
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Doklady Biological Sciences 426:244-6.
