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The Lancet 07/2009; 373(9679):1944; author reply 1944-5. · 38.28 Impact Factor
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ABSTRACT: This prospective study was conducted on 108 consecutive implantations straight, cementless, taper-designed stem with variable lateral flare (Pegasus; DePuy, Warsaw, Indiana) at an 8- to 10-year follow-up; DEXA scanning was performed at 3 and 12 months on a second cohort of 40 patients. The mean Harris hip score was 94.2, and no revision was performed. Measurable subsidence of the stem was found in three (2.8%) patients; the subsidence was always measured within the first year of follow-up, and did not progress at the subsequent controls. Bone mineral density decreased at 1 year, 15.1% in zone 1 and 3.4% in zone 7. Uncemented stems with a taper design, which provide a high metaphyseal fit and a low diaphyseal fit, lead to comparable and reproducible long-term results independently from other design characteristics.
Orthopedics 12/2007; 30(11):954-8. · 2.66 Impact Factor
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ABSTRACT: The packaging and chemical stability of both conventional and highly crosslinked polyethylene (PE) components available for clinical use in Italy were analyzed. A total of 100 sterilized PE components were entered by 18 orthopedic manufacturers into the study. Six of the manufacturers were Italian and the remaining were based in Europe or America. Hydroperoxide, oxidation, and trans-vinylene levels within the PE components were characterized using Fourier-transform infrared spectroscopy (FTIR). None of the 31 gas-sterilized components had detectable free radicals, hydroperoxide content, or oxidation. Among radiation-sterilized inserts, the highest oxidation and hydroperoxide levels were associated with gas-permeable and polymer-barrier packaging. To the authors' knowledge, this is the first study that relates elevated oxidation and hydroperoxide content in gamma-sterilized PE components to certain types of contemporary, polymeric barrier packaging.
Journal of Biomedical Materials Research Part B Applied Biomaterials 07/2006; 78(1):20-6. · 2.15 Impact Factor
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Paolo Gallinaro
Orthopedics 02/2005; 28(1):13-4. · 2.66 Impact Factor
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ABSTRACT: Hydatid disease involves mainly the liver (66% of the cases) and the lungs (22%), with skeletal involvement being reported in 0.5-2.5% of cases.
Herein is reported a case of hydatidosis of the hip and pelvis with a follow-up of 25 years. The diagnosis was first done in April 1975 following the local excision of a single hydatid cyst from the ischium of a 25-year-old man complaining of increasing pain and swelling of the left thigh. Histology confirmed hydatid disease of the bone. Local excision was repeated four more times for recurrence of the hydatid cysts in the bone or soft tissues. Antiparasitic medical therapy (albendazole 10 mg/kg daily) was attempted in 1991 but suspended after 2 days due to systemic adverse effects (abdominal pain, diarrhea). The patient had a 12-year relapse-free period with complete absence of any symptoms.
Such a long symptom-free period confirms that it is not possible to consider bone hydatidosis as being completely healed without the confirmation of a long term follow-up.
Archives of Orthopaedic and Trauma Surgery 05/2004; 124(3):203-5. · 1.37 Impact Factor
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ABSTRACT: IntroductionHydatid disease involves mainly the liver (66% of the cases) and the lungs (22%), with skeletal involvement being reported in 0.5–2.5% of cases.Case reportHerein is reported a case of hydatidosis of the hip and pelvis with a follow-up of 25years. The diagnosis was first done in April 1975 following the local excision of a single hydatid cyst from the ischium of a 25-year-old man complaining of increasing pain and swelling of the left thigh. Histology confirmed hydatid disease of the bone. Local excision was repeated four more times for recurrence of the hydatid cysts in the bone or soft tissues. Antiparasitic medical therapy (albendazole 10mg/kg daily) was attempted in 1991 but suspended after 2days due to systemic adverse effects (abdominal pain, diarrhea). The patient had a 12-year relapse-free period with complete absence of any symptoms.ConclusionSuch a long symptom-free period confirms that it is not possible to consider bone hydatidosis as being completely healed without the confirmation of a long term follow-up.
Archives of Orthopaedic and Trauma Surgery 03/2004; 124(3):203-205. · 1.37 Impact Factor
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Paolo Gallinaro
The Lancet 04/2002; 359(9308):785. · 38.28 Impact Factor