Mikihisa Fukuda

Publications (3)3.43 Total impact

• Article: [A case of M. avium lung disease complicated with adenocarcinoma].

  Kanako Kobayashi, Shuichi Yano, Kazuhiro Kato, Hiroki Yajima, Shinji Saito, Masanari Watanabe, Mikihisa Fukuda
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  ABSTRACT: A 56-year-old man was admitted to our hospital for examination of an abnormal shadow found in a chest radiograph. Chest CT demonstrated a thick-walled cavity surrounded by small centrilobular nodules in the upper lobe of the left lung. Chemotherapy with rifampin, isoniazid, ethambutol and pyrazinamide was started, because acid-fast bacilli were observed in the bronchial brushing smear. Since PCR examination of the bronchial lavage was positive for M. avium, the rifampin and ethambutol were retained, while the other drugs were replaced with streptomycin and clarithromycin. However, in this case the radiographic findings did not point to non-tuberculous mycobacterial (NTM) infection, since the thickness of the cavity was irregular in the caudal portion. In addition, the patient did not accept long-term NTM therapy. Therefore, we chose surgical therapy. In a portion of the surgical specimen, adenocarcinoma was detected. The possibility of lung cancer should be remembered in cases with a thick-walled lung cavity.
  Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society. 04/2003; 41(3):177-80.
• Article: Comparison of three tracers for detecting sentinel lymph nodes in patients with clinical N0 lung cancer.

  Kazuro Sugi, Mikihisa Fukuda, Hiroshige Nakamura, Yoshikazu Kaneda
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  ABSTRACT: The goal of this pilot study was to compare three tracers for the detection of sentinel nodes in patients with lung cancer. Forty-eight patients with clinical N0 non-small cell lung cancer were enrolled. Indocyanine green (n=16) or isosulfan blue (n=18) was injected around the tumor intraoperatively, or technetium tin colloid was injected preoperatively under CT guidance (n=14). Sentinel nodes were detected in 6.3% of patients injected with indocyanine green, 50.0% of patients injected with isosulfan blue, and 64.3% of patients injected with technetium tin colloid. The detection rate achieved with indocyanine green was significantly lower than with the other two tracers. A false-negative sentinel node was seen in 1 patient using isosulfan blue. Both isosulfan blue and technetium tin colloid seem to be suitable for intraoperative sentinel node mapping in patients with lung cancer.
  Lung Cancer 02/2003; 39(1):37-40. · 3.43 Impact Factor
• Article: [Successful outpatient treatment with chemotherapy of weekly gemcitabine and vinorelbine for a patient with recurrent lung cancer].

  Yuji Kawasaki, Kazuhiro Kato, Kanako Kobayashi, Shuuichi Yano, Shinji Saito, Mikihisa Fukuda, Masanori Miyata, Eiji Shimizu
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  ABSTRACT: A 68-year-old man with recurrent lung cancer was treated with chemotherapy of weekly gemcitabine and vinorelbine on an outpatient basis. After 2 cycles of the regimen, shadows in the lung completely disappeared. During this treatment, the patient's condition was good. This regimen seems to be effective in maintaining QOL and may be suitable for outpatients.
  Gan to kagaku ryoho. Cancer & chemotherapy 02/2002; 29(1):107-9.