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ABSTRACT: Schwannoma arising from the kidney is a rare benign tumor, with only 20 cases reported in the English literature. We encountered a histopathologically typical Schwannoma of the kidney in a 39-year-old woman, which was characterized by marked calcification. Radical nephrectomy was performed under the diagnosis of renal cell carcinoma. The 21 reported cases of schwannoma of the kidney, including the present case, are reviewed in detail.
Hinyokika kiyo. Acta urologica Japonica 11/2005; 51(10):663-7.
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ABSTRACT: Although many factors have been reported as predictors of the recurrence of renal cell carcinoma (RCC), none of the factors are consistent among different studies. In the study presented here, the potential clinicopathological predictors of the recurrence of N0M0 RCC were examined.
A total of 201 patients who underwent nephrectomy for N0M0 RCC were examined to determine the pathological tumor stage (pT stage), pathological tumor grade of malignancy (tumor grade), symptoms, and tumor size.
RCC recurred in 29 patients (14.4%), 50% of whom developed new tumors within 24 months after nephrectomy. The disease-free 3- and 10-year survival rates declined as the pT stage and tumor grade increased: these rates were, respectively, 98.6% and 86.5% for pT1a; 93.7% and 87.9% for pT1b; 100% and 100% for pT2; 78.6% and 58.0% for pT3a; and 88.9% and 16.7% for pT3b. Significant differences in the recurrence rate were noted between pT3 and pT1 or pT2, as well as between grade 3 disease and grade 1 or grade 2 tumors. Multivariate analysis showed that a combination of the pT stage, grade, and presence of symptoms was useful for predicting the recurrence of RCC.
The present study showed that patients undergoing nephrectomy for N0M0 RCC should be followed-up carefully for 2 years postoperatively with special attention to high pT stage, high grade, and the development of symptoms.
International Journal of Urology 11/2003; 10(10):511-7. · 1.75 Impact Factor
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ABSTRACT: Positron emission tomography (PET) is now primarily used in oncological indication owing to the successful application of fluorine-18 fluorodeoxyglucose (FDG) in an increasing number of clinical indications. Glucose transporter 1 (GLUT-1) is recognized as a major early marker of cellular malignant transformation. The aims of this study were to assess whether FDG-PET is a useful diagnostic tool for renal cell carcinoma and to compare the pathologic characteristics.
Nineteen consecutive patients who had renal cell carcinoma were examined using FDG-PET preoperatively. The results of PET were then compared to the histology obtained after radical surgery and the immunoreactivity of GLUT-1 was also studied.
Pathologic examination confirmed that all 19 patients suffered from renal cell carcinoma. Increased FDG uptake was found in six of the 19 patients (31.5%). The immunohistochemical examination of GLUT-1 in renal cell carcinoma produced different results in each patient. There was no correlation with GLUT-1 immunoreactivity and FDG-PET positivity.
These results suggest that FDG-PET may not be a useful diagnostic tool for renal cell carcinoma.
International Journal of Urology 02/2002; 9(1):15-8. · 1.75 Impact Factor
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ABSTRACT: Testosterone secreting adrenal adenoma is rare. We recently experienced a 17-year-old pubertal girl who showed signs of virilization and a high serum level of testosterone. The excised adrenal gland showed a 3.5 × 3 × 3-cm cortical adenoma. Light and electron microscopic findings together with the high serum level and high tumor tissue contents of testosterone and dehydroepiandrosterone (DHA) indicated that the tumor was a testosterone-secreting adrenal cortical adenoma. This appears to be a rather rare tumor from a review of the literature. Interestingly, in this case, the cytoplasm of the tumor cells contained structures resembling spironolactone bodies. From the results of enzyme histo-chemistry, the steroidogenetic pathways in this tumor were speculated. Acta Pathol Jpn 40: 67–72, 1990.
Pathology International 12/1989; 40(1):67 - 72. · 1.62 Impact Factor
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ABSTRACT: Ofloxacin was administered to 26 males infected with Ureaplasma urealyticum. The infection was confirmed by urine or semen culture. Ofloxacin, administered at daily dose of 300-600 mg for 7 to 28 days, eradicated U. urealyticum in 25 of 26 patients (92.2%).
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ABSTRACT: 今日,膣トリコモナスの臨床材料からの検出には, 市販の培地が使用されているが, その検出感度は必ずしも満足できるものではない。感度のよい培地には保存性がわるいなどの欠点がある。泌尿器科的立場からより好ましい培地を追求し,今回新しく肝エキスを除いた培地について従来の日水培地, 浅見培地と比較し, この2種の培地の中間に位置する検出感度であることをたしかめた。 For demonstration of Trichomonas vaginalis, commercial liquid media commonly used in most clinical laboratories but none has proven to be fully satisfactory in respect of presrvation, trichomonad detect ability and price. Experiments were performed to assess usefulness of a trial preparation of liver extract-free medium. The results indicate that the new medium is superior to the conventional media with respect to cost and preservability but there is no appreciable difference in trichomonad detectability between them.
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ABSTRACT: 膣トリコモナス虫体内のdehydrogenase各種を染色法で検討してみた。LDH,Aldolase,AlcDH,M DH,の活性は虫体内にみとめられたが,αKeto DH,SDH, ICDH にはあまり活性がみとめられなかった。