Soumya Bhattacharya

Medical College Kolkata, Calcutta, Bengal, India

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Publications (6)6.93 Total impact

  • Article: A rare mediastinal tumour in a young male mimicking massive pleural effusion.
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    ABSTRACT: A 30-year-old male, carpenter by profession, presented with a history of dry cough and progressive shortness of breath for two months along with right-sided chest pain for one and a half months. The clinico-radiological picture was suggestive of right-sided massive pleural effusion. Computed tomography (CT) scan of the thorax showed a huge mediastinal mass occupying the entire right hemithorax with very small amount of pleural effusion. CT-guided fine needle aspiration cytology and tru-cut biopsy from the mass both revealed small round-cell tumour, possibly small cell carcinoma of the lung. However, on immunohistochemistry tumour cells expressed Mic-2 and it was consistent with a diagnosis of primitive neuroectodermal tumour.
    Lung India 01/2012; 29(1):66-9.
  • Article: Identification of orcinol reactive substance in pleural fluid cell lysate--a new parameter for classification of pleural effusion.
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    ABSTRACT: Cell-free DNA is observed to be more in exudative pleural effusions. Based on this fact development of a clinical chemistry test for classification of pleural effusion will require DNA extraction followed by PCR amplification and electrophoresis. These procedures may not be cost effective for the purpose for classification of pleural effusion as already established parameters are popular for the purpose which can be estimated by comparatively low cost colorimetric procedures. Therefore development of a simple colorimetric test for the classification of pleural fluid based on nucleic acid identification test can be attempted. The aim of this work is to develop such colorimetric test for classification of pleural effusion using only pleural fluid sample. Cell pellet is obtained from 5 ml pleural fluid which is lysed and subjected to DNA extraction, followed by identification under UV-transilluminator after electrophoresis and orcinol and diphenylamine reaction. Exudates show extractable DNA from 5 ml biofluid (n=52) which are not observed from transudate (n=32). Orcinol reaction is significantly positive in exudates (n=52) compared to the transudates (n=32). Diphenylamine test cannot differentiate exudate from transudate. Orcinol reaction of cell lysate obtained from pleural fluid can classify pleural fluid sample into exudate or transudate.
    Clinica chimica acta; international journal of clinical chemistry 02/2010; 411(9-10):671-4. · 2.54 Impact Factor
  • Article: Non-renal Wegener's granulomatosis in a young housewife.
    Journal of the Indian Medical Association 02/2009; 107(1):45.
  • Article: Preliminary evaluation of a hybrid problem-based learning curriculum.
    Medical Education 06/2008; 42(5):518. · 3.18 Impact Factor
  • Source
    Article: Assessment of pulmonary function in local healthy Nepalese men of Dharan and it's anthropometric correlation.
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    ABSTRACT: Healthy non smoking male subjects (n = 150) aged 18-40 years were subjected to pulmonary function testing to establish linear multiple regression model. Pulmonary parameters were considered as independent variables and physical parameters (age, height, weight, body mass index (BMI) and body surface area (BSA) and anthropometric parameters (skin fold thickness (SFT), mid arm circumference and abdominal girth) were taken as dependent variables. This study was undertaken to determine correlation coefficients between dependent variables and different pulmonary independent variables and to derive regression equations or prediction formulae in order to find out the expected normal values for the different lung function tests in a given individual. Present study revealed that the upper body fat distribution, as reflected by biceps skin fold thickness and mid arm circumference, is a significant predicator of ventilatory function.
    Nepal Medical College journal : NMCJ. 10/2007; 9(3):191-5.
  • Article: A global diagnostic tool for measuring educational environment: comparing Nigeria and Nepal.
    Sue Roff, Sean McAleer, O. S. Ifere, Soumya Bhattacharya
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    ABSTRACT: The paper reports comparative data from a Nigerian undergraduate medical school and a Nepalese health professions institution in order to explore the value of the previously reported Dundee Ready Education Environment Measure (DREEM) in 'diagnosing' the environment and climate of particular institutions and making comparative analyses in two culturally diverse situations. The Nigerian undergraduate medical school scored 118 out of a possible 200 on the DREEM global score. There were significant differences on five of the items between the male and female students and several significant differences on individual items between the students in Years 4 and 5, Years 5 and 6, and Years 4 and 6. The Nepalese global score was 130/200 and there were significantly different scores for six items between the male and female students. The scores for Years 1-3 also showed several significantly different items. These scores permitted two distinct 'diagnoses' of the two medical schools.
    Medical Teacher 08/2001; 23(4):378-382. · 1.22 Impact Factor