Shivali Sehgal

Lady Hardinge Medical College, New Dilli, NCT, India

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Publications (6)2.89 Total impact

  • Anita Nangia, Shivali Sehgal, Ram Chander
    Journal of Cytology 07/2014; 31(3):180-1. DOI:10.4103/0970-9371.145668 · 0.41 Impact Factor
  • Indian Journal of Pathology and Microbiology 04/2014; 57(2):344-5. DOI:10.4103/0377-4929.134746 · 0.64 Impact Factor
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    ABSTRACT: Breast hamartomas (BH) or Fibroadenolipoma are extremely rare breast lesions. They are benign, focal malformation that resembles a neoplasm in the tissue of its origin. We describe a case of a 48 years woman with bilateral breast lumps for the past 18 months and 6 months which were gradually increasing in size. FNAC smears revealed only clusters of benign ductal epithelial cells. Lumps were excised and histopathology revealed predominantly stromal smooth muscle bundles (proved by immunohistochemistry) along with scattered intact terminal duct-lobular units, dilated ducts and entrapped islands of mature fibroadipose tissue. A diagnosis of Bilateral Myoid hamartoma of breast was given. To the best of our knowledge till date no case of bilateral MH of breast been reported in the literature. We report the first case of bilateral MBH highlighting its morpho-immunophenotypic features.
    Breast disease 08/2013; DOI:10.3233/BD-130355
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    04/2013; 4(2):156-7. DOI:10.4103/2229-5178.110644
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    ABSTRACT: OBJECTIVE: Malaria is highly prevalent and endemic in tropical countries and carries a significant health burden. The detection of malaria by light microscopy of Giemsa-stained smears is the gold standard. There are many hematological abnormalities associated with malaria like anemia, thrombocytopenia, and leucopenia; however, none of these abnormalities are specific. The present study was undertaken to assess the utility of WBC scattergram in predicting the diagnosis of malaria. METHODS: In this study all cases diagnosed as Plasmodium vivax/Plasmodium falciparum infection on peripheral smear examination were included. Their complete blood counts and WBC scattergrams obtained from XT2000i were critically evaluated. Accordingly, sensitivity, specificity, positive predictive value (PPV), and negative predictive value of detection of malaria by abnormal WBC scattergram with and without abnormal blood counts were also calculated. RESULTS: A total of 2251 ethylendiaminetetraacetic acid samples were run on XT2000i hematology autoanalyzer. Out of these 148 cases of malaria were diagnosed on peripheral smear (128 P. vivax and 20 P. falciparum). While analyzing the WBC scattergrams, 233 cases including 124 (83.8%) malaria cases showed different abnormalities. Sensitivity and PPV for the diagnosis of malaria by abnormal WBC scattergram were 83.78 and 53.20%, respectively. This had increased to 98.60 and 57.25%, respectively, when cytopenias were included. DISCUSSION: Sysmex XT-2000i is capable of detecting specific abnormalities in WBC scattergram in patients with malaria. Therefore, the presence of an abnormal WBC scattergram with thrombocytopenia in a febrile patient helps the pathologist to clinch the diagnosis of malaria.
    Hematology (Amsterdam, Netherlands) 09/2012; 18(2). DOI:10.1179/1607845412Y.0000000029 · 1.19 Impact Factor
  • Indian Journal of Pathology and Microbiology 01/2012; 55(1):134-5. DOI:10.4103/0377-4929.94901 · 0.64 Impact Factor