Jana Jašková

Publications (3)0 Total impact

• Article: Synthesis, spectral properties, crystal structures and biological activity of copper(II) pyridinecarboxylates with N -heterocyclic ligands

  Peter Segl'a, Dušan Mikloš, Jana Jašková, Jozef Miklovič, Barbora Kaliňáková, Daniela Hudecová, Jozef Švorec, Tadeusz Lis, Milan Melník
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  ABSTRACT: Synthesis and characterization of four new 2,6-dimethoxynicotinate (2,6-(MeO)2nic) copper(II) monomeric complexes [Cu(2,6-(MeO)2nic)2(py)2] (py is pyridine), [Cu{2,6-(MeO)2nic}2(Etnic)2(H2O)] (Etnic is ethylnicotinate), [Cu{2,6-(MeO)2nic}2(Et2nia)2(H2O)2] (Et2nia is N,N-diethylnicotinamide) as well as of the polymeric complex [Cu{2,6-(MeO)2nic}2(ron)2] n (ron is ronicol) are reported. The characterizations were based on elemental analysis, infrared, electronic and EPR spectra. Crystal structures of two of the complexes have been determined. The copper(II) of [Cu{2,6-(MeO)2nic}2(py)2] has a distorted tetragonal-bipyramidal (4 + 2) coordination environment. Both 2,6-(MeO)2nic anions are asymmetrically chelating. The Cu(II) of [Cu{2,6-(MeO)2nic}2(Etnic)2(H2O)] is pentacoordinate in a slightly distorted tetragonal-pyramidal arrangement by two trans nitrogens, each of one Etnic, by two oxygens, each of the carboxyl group of one unidentate 2,6-(MeO)2nic and the axial position occupied by water at a longer distance. Antimicrobial effects of the complexes have been tested on various strains of bacteria, yeasts and filamentous fungi. While the 2,6-(MeO)2nicH alone did not influence the model bacteria growth, dimeric [Cu{2,6-(MeO)2nic}2(H2O)]2 and polymeric [Cu{2,6-(MeO)2nic}2(ron)2] n have pronounced influence on the growth of Staphylococcus aureus, Escherichia coli and Candida parapsilosis.
  Journal of Coordination Chemistry. 12/2008; 61(23):3763-3775.
• Article: Innersphere transformations of pyridine-2-carbonitrile mediated by copper(II), cobalt(II) and nickel(II). Crystal structures of bis (nitrato)- bis ( N -2-hydroxyethyl- pyridine-2-carboxamidine- N,N ′)copper(II) and bromo-bis( N -3-hydroxy-propylpyridine-2-carboxamidine- N,N ′)copper(II) bromide

  Jana Jašková, Dušan Mikloš, Peter Segl'a, Marian Koman, Milan Melnik, Tadeusz Glowiak
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  ABSTRACT: Condensation of pyridine-2-carbonitrile (2-CNpy) with 2-aminoethanol (L1) or 1-amino-3-propanol (L2) in alcohol solutions of CuX2 (X =  , , Cl− and Br−) proceeds readily under mild conditions to form stable solid complexes [Cu(NO3)2(amL1-NH)2], [Cu(amL1-NH)2](ClO4)2, [Cu(amL2-NH)2](ClO4)2, [CuCl2(amL2-NH2)] · H2O, [CuCl2(amL2-NH)2] and [CuBr(amL2-NH)2]Br, which contain the imino form of N-2-hydroxyethylpyridine-2-carboxamidine (amL1-NH) and imino or amino forms of N-3-hydroxypropylpyridine-2-carboxamidine (amL2-NH or amL2-NH2). Crystal structures of [Cu(NO3)2(N-2-hydroxyethyl-pyridine-2-carboxamidine-N,N′)2] and [CuBr(N-3-hydroxypropylpyridine-2-carboxamidine-N,N′)2]Br and IR data confirm bidentate N,N-coordination of N-hydroxyalkylpyridine-2-carboxamidines (via the nitrogen atom of the pyridine ring as well as the nitrogen atom of the terminal imino group). The structure of [Cu(NO3)2(amL1-NH)2] consists of well-separated centrosymmetrical Cu(amL1-NH)2(NO3)2 entities, including two independent kinds of molecules (molecule [Cu(NO3)2(amL1-NH)2] and molecule [Cu(amL1-NH)2](NO3)2) with central atoms Cu1 and Cu2 located at two crystallographically independent symmetry centres. [CuCl2(amL2-NH2)] · H2O contains only a terdentate N,N,O-coordinated amino form of N-3-hydroxypropylpyridine-2-carbox-amidine (amL2-NH2). The analogous reaction of 2-CNpy with L2 and M(NCS)2 (M = Ni and Co) in ethanol leads to the solid complexes [Co(NCS)2(oxaL2)2] · 2H2O and [Ni(NCS)2(oxaL2)2], which contain 2-pyridinyl-1,3-oxazine (oxaL2). Based on the molecular structure, electronic and IR spectroscopic data are discussed.
  Journal of Coordination Chemistry. 03/2007; 60(5):527-537.
• Article: Preparation, Structure, Spectral, and Magnetic Properties of Copper(II) Halogenonicotinates: Crystal and Molecular Structure of Tetrakis(μ‐2‐chloronicotinato‐O,O′)‐diaquadicopper(II)

  Jan Moncol, Maria Korabik, Peter Segl'a Dr, Marian Koman, Dušan Mikloš, Jana Jašková, Tadeusz Glowiak, Milan Melník, Jerzy Mrozinski, Markku R. Sundberg
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  ABSTRACT: The characterization of the complexes [Cu2(2-Clnic)4(H2O)2] (1), [Cu(2,6-Cl2nic)2(H2O)2] (2) and [Cu(5-Brnic)2(H2O)2]n (3) (where 2-Clnic = 2-chloronicotinate, 2,6-Cl2nic = 2,6-dichloronicotinate or 5-Brnic = 5-bromonicotinate) was based on elemental analysis, IR, electronic and EPR spectra, and magnetic susceptibility. Complex 1 was also studied by X-ray analysis at 298 1a and 80 K 1b. The complex 1 contains a dinuclear Cu-acetate molecular structure in which the carboxyl groups of the 2-chloronicotinate ligands act as bridges and water molecules are at apical positions. The stereochemistry about Cu atom at both temperatures is typical for square pyramidal geometry with CuO4O chromophore. The Cu-Cu distance is 2.6513(8) and 2.6382(6) Å for 1a and 1b, respectively. The Cu atoms are displaced by 0.2069(9) and 0.1973(7) Å, respectively, from the plane containing four oxygen atoms bonded to the Cu atom toward the apical water molecules. Strong and weak hydrogen bonds as well as C–Cl···π interactions in the crystal structure are discussed as well. Both complexes, monomeric [Cu(2,6-Cl2nic)2(H2O)2] (2) and polymeric [Cu(5-Brnic)2(H2O)2]n (3), possess octahedral copper(II) stereochemistry with differing tetragonal distortions.
  Zeitschrift für anorganische Chemie 01/2007; 633(2):298 - 305.