ABSTRACT: The objective of this study was to determine alterations in neutrophils after an acute bout of short duration exercise (swimming) in sedentary rats. Male Wistar rats were assigned to the following groups (controls and exercised groups at low and moderate intensities of exercise. Peritoneal neutropenia was observed (p≤0.05) in the 15-minute at low intensity group (54x106±3.5). Peritoneal neutrocytosis was observed after 5-minutes at both intensities (178.8x106±11.4 and 173.2x106±3.1, low and moderate groups, respectively), as well as a reduction in the phagocytic capacity of peritoneal neutrophils after 5 minutes (78%±1.3 and 74.8%±3, low and moderate groups, respectively). Viable circulating neutrophils were increased at 5-minutes (96.4%±0.6 and 94.2%±1, low and moderate intensities, respectively), but no changes in apoptotic parameters were observed. Collectively, these data indicate that the stress of an acute bout of exercise results in significant alterations in neutrophils, without inducing apoptosis.
Journal of Exercise Physiology Online 01/2007; 10(6):27-36.