Publications (1)13.45 Total impact
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Article: Cooperative assistance in bifunctional organocatalysis: enantioselective Mannich reactions with aliphatic and aromatic imines.
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ABSTRACT: Hold them tight: Guided by X-ray structures, bifunctional thiourea catalysts containing an activating intramolecular hydrogen bond were redesigned. The new catalysts were used to effect a highly enantioselective Mannich reaction between malonates and both aliphatic and aromatic imines (see scheme; Boc=tert-butoxycarbonyl).Angewandte Chemie International Edition 07/2012; 51(34):8495-9. · 13.45 Impact Factor
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2012
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Jyväskylän yliopisto
- Department of Chemistry
Jyväskylä, Western Finland, Finland
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