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    ABSTRACT: The study aimed to investigate the effects of age, body mass index and nutritional assessment system score, levels of vitamins A, C, E and beta-carotene in surgical patients with different diagnosis. 163 patients hospitalized at Gazi University Medical School, Department of General Surgery were prospectively analyzed. Patients were grouped as younger (Group 1, n=110), and older (Group 2, n=53) than 60 years. Nutritional statuses were classified as normal, moderately malnourished, and severely malnourished. The serum vitamin levels were investigated with comparisons of age, gender, primary surgical disease (benign or malign), and BMI. Correlations between BMI, age and vitamin levels were evaluated. Group 2 had significantly worse nutritional status and more malign diseases than group 1. Vitamin A, C, E and beta carotene levels was found low in 20 %, 39%, %6, and 7 % of the patients in group 1 and 60%, 81%, 15%, 30% of patients in group 2 respectively. Vitamin levels were low in malnourished patients. BMI of the patients were in correlation with the vitamin levels. Body mass index was in correlation with the serum vitamin levels. Supplementation of vitamins A and C can be beneficial in elderly patients.