Smaranda Leu-Semenescu

Publications (1)4.51 Total impact

• Article: A single-question screen for rapid eye movement sleep behavior disorder: a multicenter validation study.

  Ronald B Postuma, Isabelle Arnulf, Birgit Hogl, Alex Iranzo, Tomoyuki Miyamoto, Yves Dauvilliers, Wolfgang Oertel, Yo-El Ju, Monica Puligheddu, Poul Jennum, Amelie Pelletier, Christina Wolfson, Smaranda Leu-Semenescu, Birgit Frauscher, Masayuki Miyamoto, Valerie Cochen De Cock, Marcus M Unger, Karin Stiasny-Kolster, Maria Livia Fantini, Jacques Y Montplaisir
  [show abstract] [hide abstract]
  ABSTRACT: Idiopathic rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia that is an important risk factor for Parkinson's disease (PD) and Lewy body dementia. Its prevalence is unknown. One barrier to determining prevalence is that current screening tools are too long for large-scale epidemiologic surveys. Therefore, we designed the REM Sleep Behavior Disorder Single-Question Screen (RBD1Q), a screening question for dream enactment with a simple yes/no response. Four hundred and eighty-four sleep-clinic-based participants (242 idiopathic RBD patients and 242 controls) completed the screen during a multicenter case-control study. All participants underwent a polysomnogram to define gold-standard diagnosis according to standard criteria. We found a sensitivity of 93.8% and a specificity of 87.2%. Sensitivity and specificity were similar in healthy volunteers, compared to controls or patients with other sleep diagnoses. A single-question screen for RBD may reliably detect disease, with psychometric properties favorably comparable to those reported for longer questionnaires.
  Movement Disorders 06/2012; 27(7):913-6. · 4.51 Impact Factor