Lin Dong

Publications (2)11.79 Total impact

• Article: Rhodium(III)-Catalyzed Direct Selective C(5)-H Oxidative Annulations of 2-Substituted Imidazoles and Alkynes by Double C-H Activation.

  Ji-Rong Huang, Qian-Ru Zhang, Chuan-Hua Qu, Xun-Hao Sun, Lin Dong, Ying-Chun Chen
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  ABSTRACT: Double C-H activations of C(5)-H and Csp(2)-H of 2-substituted N-vinyl- or arylimidazoles were realized without heteroatom-directing assistance by rhodium(III) catalyst. A subsequent oxidative annulation reaction with alkynes efficiently produced aza-fused heterocycles with high molecular complexity in low to excellent yields.
  Organic Letters 03/2013; · 5.86 Impact Factor
• Article: Synthesis of aza-fused polycyclic quinolines via double C-H bond activation.

  Ji-Rong Huang, Lin Dong, Bo Han, Cheng Peng, Ying-Chun Chen
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  ABSTRACT: Simple but efficient: Aza-fused polycyclic quinolines were efficiently assembled through rhodium(III)-based direct double C-H activation of N-aryl azoles followed by cyclization with alkynes without heteroatom-assisted chelation. Copper(II) acetate, aside from acting as an oxidant, could also play an important role in the C-H activation process.
  Chemistry 06/2012; 18(29):8896-900. · 5.93 Impact Factor