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Publications (4)1.05 Total impact

  • 09/2013; 35(3):429-433. DOI:10.7197/1305-0028.1962
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    ABSTRACT: Aim: To prospectively compare the sensitivity of Wang 22-gauge needle aspiration and 19-gauge needle aspiration with bronchial biopsy and determine whether there was difference between 22-gauge and 19-gauge needle aspirations in the diagnosis of endobronchial malignancies. Materials and methods: All patients (63 patients) in the study underwent fiberoptic bronchoscopy that included 22-gauge needle aspiration and 19-gauge needle aspiration. In 50 patients bronchial biopsy was done. The sensitivities of the individual techniques were compared. Results: Cancer was diagnosed in 48 patients by 22-gauge needle aspiration and 19-gauge needle aspiration, and in 43 patients by bronchial biopsy. The sensitivity of bronchial biopsy was 0.86. The addition of 22-gauge and 19-gauge needle aspirations to bronchial biopsy increased the sensitivity to 0.90 and 0.88, respectively, but the difference was not statistically significant (P = 1.0). The maximal diagnostic yield was obtained with the combination of needle aspirations and forceps biopsy in the detection of submucosal or peribronchial bronchogenic carcinoma (100%) (P < 0.05). Conclusion: The combination of forceps biopsy and transbronchial needle aspirations should be used for the highest rate of bronchoscopic diagnostic yield. However, there was no difference for increasing diagnostic yield in patients with visible endobronchial lesions between 22-gauge and 19-gauge needles.
    Turkish Journal of Medical Sciences 06/2011; 41(3). DOI:10.3906/sag-1008-998 · 0.84 Impact Factor
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    ABSTRACT: Sarcoidosis is a systemic granulomatous disease of unknown cause that commonly involves the lungs, lymph nodes, bones, liver, spleen, or skin. Cutaneous findings of sarcoidosis occur in 20% to 35% of patients with systemic disease. The recognition of cutaneous lesions is important, because it gives important clues to diagnosis and also allows for easy biopsy. We report a 71-year-old Turkish woman with erythematous lesions, which included widespread, erythematous macules of various sizes on the chest, abdomen, and back on both sides of her body. Fine white scales covered some of the lesions. Hepatomegaly and bilateral hilar lymphadenopathy were also observed. Biopsy specimens of the skin showed dermal, noncaseating, epitheloid granulomas. The diagnosis, based on correlation of the clinical presentation and histopathological findings, was ichthyosiform sarcoidosis with systemic involvement. The difference between our case and other cases of ichthyosiform sarcoidosis described in the literature is that ours involved only the trunk and not the extremities. We are presenting this case because it is an interesting and rare variant of ichthyosiform sarcoidosis.
    Central European Journal of Medicine 09/2009; 4(3):388-390. DOI:10.2478/s11536-009-0037-2 · 0.21 Impact Factor
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    ABSTRACT: Although peripheral giant cell granulomas (PGCG) develop mainly within soft tissue, on rare occasions they may involve underlying bone and become visible radiologically. In such cases, the diameter of the hemorrhagic lesion rarely exceeds 20 mm, and pain is uncommon. This paper describes the successful treatment of two cases of huge PGCGs that led to alveolar bone resorption.INTRODUCTION Peripheral giant cell granulomas (PGCG) are relatively uncommon reactive exophytic lesions of the oral cavity. 1-4 Although PGCGs may be observed at any age, they are reportedly more common among individuals in their 50s and 60s, present slightly more frequently in the mandible than in the maxilla and have a slightly higher incidence in females than males. 1,3-5 PGCGs may develop at the interdental papilla, gum or edentulous alveolar margins. These hemorrhagic lesions rarely exceed 2 cm in diameter, may be pedunculated or sessile, are red or reddish blue in colour and reveal an elastic structure on palpation. 1-5 PGCGs tend to be asymptomatic; however, while pain is uncommon, the lesion may become ulcerated as a result of repeated trauma. 2,5 PGCG very rarely affects the underlying bone, although the latter may suffer superficial erosion.