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ABSTRACT: The aim of this study was to investigate the effects of persimmon-vinegar supplementation on blood lipid profiles, carnitine
concentrations, and hepatic mRNA levels of enzymes involved in fatty acid metabolism. Thirty-two C57BL/6J male mice were divided
into 4 groups; control group (HD), industrial vinegar group (HD-V), and persimmon-vinegar groups (HD-PV1, HD-PV2). Serum triglyceride
(TG) and total cholesterol (TC) concentrations significantly decreased in all vinegar-administered groups compared with the
HD group. The hepatic TG and TC concentrations of persimmon-vinegar administered groups were significantly lower compared
with the HD group. Liver acid insoluble acylcarnitine (AIAC) was significantly higher in the HD-PV2 than in HD and HD-V groups.
The acetyl-CoA carboxylase (ACC) mRNA level tended to lower in all the vinegar administered groups compared with the HD group.
These results suggest that the persimmon-vinegar has anti-obesity properties.
Keywordspersimmon-vinegar-mice-lipid profile-carnitine-hepatic mRNA level
Food science and biotechnology 04/2010; 19(2):343-348. DOI:10.1007/s10068-010-0049-3 · 0.66 Impact Factor