David B. Vodušek

Ljubljana University Medical Centre, Ljubljana, Ljubljana, Slovenia

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Publications (6)8.7 Total impact

  • David B Vodušek
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    ABSTRACT: INTRODUCTION: Clinical neurophysiological methods remain interesting research tools in urogynecology; their diagnostic role in the individual "pelvic floor" patient is, however, minor. CONCLUSION: The methods are diagnostically useful particularly in patients suspected to have a lesion involving the sphincters or the peripheral sacral nervous system, the diagnosis of which will influence management decisions or have prognostic or medicolegal relevance. Most helpful tests are the concentric needle EMG and bulbocavernosus reflex testing.
    International Urogynecology Journal 12/2011; 22(12):1473-7. · 2.17 Impact Factor
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    ABSTRACT: Urinary incontinence (UI) is a predictor of greater mortality and poor functional recovery; however published studies failed to evaluate lower urinary tract (LUT) function immediately after stroke. The aim of our study was to evaluate the course of LUT function in the first week after stroke, and its impact on prognosis. We included 100 consecutively admitted patients suffering first-ever stroke and evaluated them within 72 hours after stroke, after 7 days, 6 months, and 12 months. For LUT function assessment we used ultrasound measurement. The patients were divided into three groups: (i) patients who remained continent after stroke, (ii) patients who had LUT dysfunction in the acute phase but regained continence in the first week, and (iii) patients who did not regain normal LUT control in the first week. We assessed the influence of variables on death using the multiple logistic regression model. Immediately after stroke 58 patients had LUT dysfunction. The odds of dying in group with LUT dysfunction were significantly larger than odds in group without LUT dysfunction. Odds for death for patients who regained LUT function in 1 week after stroke were comparable to patients without LUT dysfunction. We confirmed that post-stroke UI is a predictor of greater mortality at 1 week, 6 months and 12 months after stroke. However, patients who regain normal bladder control in the first week have a comparable prognosis as the patients who do not have micturition disturbances following stroke.
    Neurourology and Urodynamics 04/2011; 30(7):1315-8. · 2.67 Impact Factor
  • D.B. Vodušek
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    ABSTRACT: Temporallappen und andere kortikale Regionen regulieren die emotionalen, kognitiven und sensomotorischen Aspekte des Sexualverhaltens; die Insula, das vordere Zingulum und der Hypothalamus koordinieren die Aktivierung des autonomen Nervensystems. Absteigende fazilitierende und inhibierende Bahnen modifizieren thorakolumbale sympathische und sakrale parasympathische und somatische Reflexzentren für genitale Erregung, Orgasmus und Ejakulation. Ein normales Hormonmilieu und vaskuläres System, aber auch ein gesunder psychosozialer Kontext sind wichtig für ein erfülltes Sexualleben. Sexualstörungen sind in der Bevölkerung, besonders bei Älteren, nicht selten und kommen noch öfter bei neurologischen Patienten vor; sie beeinflussen signifikant ihre Lebensqualität. Der Neurologe soll die Sexualstörung diagnostizieren und eine Basistherapie einleiten, die aus Aufklärung, Ratschlägen und eventuell einer Pharmakotherapie besteht. The temporal lobes and other cortical regions are involved in the emotional, cognitive and sensorimotor aspects of central control of sexual behaviour, whereas the insula, anterior cingulate and hypothalamus coordinate the activation of the autonomic nervous system. Facilitatory and inhibitory descending pathways modify the activity of thoracolumbar sympathetic and sacral parasympathetic and somatic spinal centres which control the sexual response, i.e. arousal, orgasm and ejaculation. A normal hormonal milieu and vascular system, but also a healthy psychosocial context, are necessary for a fulfilled sexual life. Sexual dysfunction is not uncommon in the general population, particularly in the elderly; it is more common in neurological patients. It significantly lowers their quality of life. The neurologist should diagnose sexual dysfunction in his patients and provide basic management including explanation, suggestions and – if necessary – drugs. SchlüsselwörterSexualität–Erektion–Orgasmus–Lubrikation–Neurologische Störung KeywordsSexuality–Erection–Orgasm–Lubrication–Neurogenic dysfunction
    Der Nervenarzt 01/2011; 82(6):787-802. · 0.80 Impact Factor
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    ABSTRACT: Striated muscle, including pelvic floor muscle (PFM) activity, is totally controlled by the nervous system. Although PFM are striated muscles and share many similarities with other striated muscles, they nevertheless differ in their control mechanisms from both limb and axial muscles, as they do not directly participate in interaction with the mechanical tasks in the external world, but rather participate in “visceral” activity.
    12/2007: pages 45-59;
  • D. B. Vodušek
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    ABSTRACT: Multiple system atrophy (MSA) is a degenerative disease manifesting a combination of parkinsonism, cerebellar, pyramidal, and autonomic (including urinary, sexual and anorectal) dysfunction. It is pathomorphologically defined, but lacks a definitive clinical diagnostic test. In patients with probable MSA, abnormal sphincter EMG, as compared to control subjects, has been found in the majority of patients in all the different forms of the disease in most studies, including patients who, as yet, have no urological or anorectal problems. Patients with Parkinson’s disease (PD) as a rule do not show marked sphincter EMG abnormalities in the first five years of the disease. Thus, abnormal spontaneous activity or marked motor unit potential changes in sphincter muscles are helpful in distinguishing MSA from PD in the first five years after the onset of symptoms and signs, and from pure autonomic failure, as well as from cerebellar ataxias, if other causes for sphincter denervation have been ruled out. EMG does not distinguish MSA from progressive supranuclear palsy. How early in the course of MSA these abnormalities become significant enough to support diagnosis remains to be established by prospective studies.
    Journal of Neural Transmission 12/2005; 112(12). · 3.05 Impact Factor
  • David B. Vodušek
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    ABSTRACT: The coordinated function of pelvic floor muscles (PFM) and related organs is an important pre-requisite that enables women to be continent of urine and feces, to micturate and defecate, and to experience orgasm. It is dependent on a complex neurocontrol consisting of voluntary muscle actions and reflexes, genetically determined activation patterns allowing for a meticulous interplay of skeletal and autonomous muscle structures, and related organs. This scientifically complicated material is broken down in this chapter to a very understandable and practical level, which is a basic necessity for sophisticated pelvic floor physiotherapy.

Publication Stats

10 Citations
8.70 Total Impact Points


  • 2005–2011
    • Ljubljana University Medical Centre
      • • Institute of Clinical Neurophysiology
      • • Department of Neurology
      Ljubljana, Ljubljana, Slovenia
  • 2007
    • University of Ljubljana
      • Department of Neurology
      Ljubljana, Ljubljana, Slovenia