A. D. Sushko

Publications (2)1.41 Total impact

• Article: Release of ribonucleic acid from human common cold HRV 2 virus in acidic medium

  A. D. Sushko, I. V. Yaminskii, E. S. Gavryushina, Yu. F. Drygin
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  ABSTRACT: The mechanism of the release of viral RNA from the capsid under the conditions that model this process in cell endosomes upon the virus infection is studied by atomic force microscopy using the human common cold virus (HRV 2 rhinovirus) as an example. Characteristic images of the RNA-protein complex resulted from the release of nucleic acid from virus at pH 4.8–6.0 are presented. It is revealed that, upon its release, RNA undergoes a number of conformational transformations in free form or in a complex with viral protein.
  Colloid Journal 04/2012; 72(4):559-564. · 0.71 Impact Factor
• Article: Comparative study of structure and properties of nucleoproteides synthesized using plant virus coat protein

  N. A. Nikitin, A. D. Sushko, M. V. Arkhipenko, N. P. Rodionova, O. V. Karpova, I. V. Yaminskii
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  ABSTRACT: The self-assembly of virus-like artificial particles from the coat protein of a helical virus (potato virus X) and nucleic acids (RNA and DNA) is studied. The structure and properties of the particles are investigated by transmission electron microscopy, atomic force microscopy, and enzymatic analysis.
  Colloid Journal 04/2011; 73(4):523-530. · 0.71 Impact Factor