İsa Öner Yüksel

Publications (2)0 Total impact

• Article: Effect of left bundle branch block on TIMI frame count

  Ayşe Saatcı Yaşar, Başar Nurcan, İsa Öner Yüksel, Kasapkara Ahmet, Tolunay Hatice, Bilge Mehmet
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  ABSTRACT: Aim: Left bundle branch block is an independent risk factorfor cardiac mortality. In this study we aimed to evaluatecoronary blood flow with TIMI frame count in patients with left bundle branch block and angiographically proven normal coronary arteries.Materials and methods: We retrospectively studied 17 patients with left bundle branch block and as a control group 16 patients without left bundle branch block. All patientshad angiographically proven normal coronary arteries.Left bundle branch block was determined according to standart electrocardiographic criteria. The TIMI frame count was measured for each major coronary artery in each patient.Results: TIMI frame count for left anterior descending coronary artery was found to be significantly higher in patientswith left bundle branch block compared with patients without left bundle branch block (35.4±16.7 ve 23.8±4.5, p=0.012). TIMI frame counts for circumflex and right coronaryarteries were similar in patients with and without left bundle branch block (TIMI frame count for circumflex artery:32.4±15.4 ve 27.7±7.6, p=0.275; TIMI frame count for right coronary artery: 31.9±9.6 ve 27.0±8.6, p=0.141).Conclusion: We have found that TIMI frame count for left anterior descending coronary artery was higher in patients with left bundle branch block compared with patients without left bundle branch block whereas there were no difference for TIMI frame counts for circumflex and right coronary arteries. Impaired coronary blood flow in left anterior descending artery may help to explain the sintigraphic perfusion defects in septum of patients with left bundle branch block.
  Dicle Medical Journal. 01/2010;
• Article: Impact of metabolic syndrome on ST segment resolution after thrombolytic therapy for acute myocardial infarction

  Ayşe Saatçı Yaşar, Başar Nurcan, Kasapkara Ahmet, İsa Öner Yüksel, İpek Göktürk, Bilge Mehmet
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  ABSTRACT: Objectives: It has been shown that metabolic syndrome is associated with poor short-term outcome and poor long-term survival in patients with acute myocardial infarction. We aimed to investigate the effect of metabolic syndrome on ST segment resolution in patients received thrombolytic therapy for acute myocardial infarction.Materials and methods: We retrospectively analyzed 161 patients, who were admitted to our clinics with acute ST-elevated-myocardial infarction and received thrombolytic therapy within 12 hours of chest pain. Metabolic syndrome was diagnosed according to National Cholesterol Education Program Adult Treatment Panel III criteria. Resolution of ST segment elevation was assessed on the baseline and 90-minute electrocardiograms. ST segment resolution ≥70% was defined as complete resolution.Results: Metabolic syndrome was found in 56.5% of patients. The proportion of patients with metabolic syndrome who achieved complete ST segment resolution after thrombolysis was significantly lower than that of patients without metabolic syndrome (32.9% versus 58.6%, p=0.001). On multivariate analysis metabolic syndrome was the only independent predictor of ST segment resolution (p=0.01, Odds ratio=2.543, %95 CI:1.248-5.179)Conclusion: The patients with metabolic syndrome had lower rates of complete ST segment resolution after thrombolytic therapy for acute myocardial infarction. This finding may contribute to the higher morbidity and mortality of patients with metabolic syndrome.
  Dicle Medical Journal. 01/2010;