ABSTRACT: In the present study, we are investigating computationally the pulsatile flow in an anatomically accurate cerebral arterial
segment exhibiting two saccular aneurysms. Our focus is on the haemodynamic patterns observed within the two aneurysms, in
terms of inflow-outflow regions, emergence and disappearance of coherent structures and mixing throughout the cardiac cycle.
The results obtained carry interesting features, important for thrombosis, pharmacokinetics and particularly for interventional
planning for aneurysm treatment. For the latter, being the center-point of this study, we show that the two aneurysms behave
in a dissimilar manner, since the blood inflow region oscillates significantly for one of them and practically does not oscillate
at all for the second. This information can guide the medical interventionist in designing the optimal approach, particularly
in cases where total obliteration of the aneurysm neck opening is impossible.
Flow Turbulence and Combustion 04/2012; 71(1):333-346. · 1.11 Impact Factor