Douglas A. Weigent

University of Alabama at Birmingham, Birmingham, AL, USA

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Publications (4)11.15 Total impact

  • Chapter: A11 Neuroimmunoendocrinology
    Douglas A. Weigent, Aletta D. Kraneveld, J. Edwin Blalock
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    ABSTRACT: Neuroimmunoendocrinology refers to the study of the interactions among behavioral, neural, neuroendocrine, and immunological processes of adaptation. Although relationships between the brain and the immune system had been suggested for many years, research mainly during the last 30 years has provided mechanisms for how these systems may interact. The current interest in neuroimmunoendocrinology is sustained by the now widely held belief that it represents a bidirectional system. The nervous system not only influences immune function, but the latter modifies the nervous system.
    12/2010: pages 179-198;
  • Chapter: Bidirectional Communication Between the Brain and the Immune System
    Douglas A. Weigent, J. Edwin Blalock
    [show abstract] [hide abstract]
    ABSTRACT: The idea that a pathway of interaction existed between the brain and the immune system has been suggested for many years. However, only the evidence gathered over the past 25 years has provided important details about the mechanisms. The clues for bidirectional communication early on related to the effects of stress on immune function and that psychological factors could alter the onset and course of autoimmune disease (Ader 1996). A list of selected findings contributing to our understanding is shown in Table 1.1. The classical (Pavlovian) conditioning of host defense mechanisms and antigen-specific immune responses was first suggested and studied in the 1920s (Metal'nikov and Chorine 1926) and later in the 1970s (Ader and Cohen 1975).
    12/2006: pages 3-25;
  • Article: Interactions between the Neuroendocrine and Immune Systems: Common Hormones and Receptors
    Douglas A. Weigent, J. Edwin Blalock
    Immunological Reviews 04/2006; 100(1):79 - 108. · 11.15 Impact Factor
  • Chapter: Neuroimmunoendocrinology
    Douglas A. Weigent, J. Edwin Blalock
    12/2004: pages 149-159;

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Institutions

  • 2006–2010
    • University of Alabama at Birmingham
      • Department of Cell, Developmental and Integrative Biology (CDIB)
      Birmingham, AL, USA
  • 2004
    • University of Alabama
      Tuscaloosa, AL, USA