Joell Gills

Publications (1)0 Total impact

• Chapter: Characterization of Natural Product Chemopreventive Agents

  John M. Pezzuto, Jerome W. Kosmeder, Eun-Jung Park, Sang Kook Lee, Muriel Cuendet, Joell Gills, Krishna Bhat, Simonida Grubjesic, Hye-Sung Park, Eugenia Mata-Greenwood, YingMeei Tan, Rong Yu, Daniel D. Lantvit, A. Douglas Kinghorn
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  ABSTRACT: Cancer is a complicated group of diseases characterized by the uncontrolled growth and spread of abnormal cells (1). In 2002, 1,284,900 new cases of cancer were estimated to be diagnosed in the United States (US), and about 555,500 persons were expected to die of cancer, i.e., more than 1500 every day (2). Despite small decreases in overall cancer incidence and mortality rates in the US since the early 1990s, the total number of recorded cancer deaths continues to increase due to an aging and expanding population (2). Furthermore, deaths from certain carcinomas of the lung and bronchus, breast, prostate, and colon and rectum remain high, and 5-yr survival rates for many cancer patients are still very low: for cancers of the brain, 32%; esophagus, 14%; liver, 6%; lung and bronchus, 15%; pancreas, 4%; stomach, 22%; and multiple myeloma, 29% (2). Obviously, cancer remains a formidable public health problem.
  12/2004: pages 3-37;