E. Basile

Istituto Regina Elena - Istituti Fisioterapici Ospitalieri, Roma, Latium, Italy

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Publications (4)4.1 Total impact

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    ABSTRACT: We developed and tested a new charged particle tracking system, able to operate in high luminosity experiments, which will be installed at Jefferson Laboratory HallA (VA, USA) for optimally exploit the new 12 GeV energy electron beam available at the end of 2013. The tracker is made of six GEM (Gas Electron Multiplier) large chambers and two 10×20 cm2 planes of SIlicon microstrip Detectors (SIDs). Each GEM chamber is composed by three 40×50 cm2 GEM modules, with two-dimensional strip readout, with expected spatial resolution of about 70μm. The same dedicated acquisition system will be used for both detectors (GEM & SID) for a grand total of more than 50,000 channels. The readout electronics is divided into two parts: the front-end cards (based on the existing APV25 chip), hosted on the detectors periphery and the digitizer, a multi purpose VME-64x/VXS board located far from the high radiation environment. The very same electronics has been adopted by the Olympus experiment (DESY, Hamburg, D) to read out the six GEM chambers of its luminosity monitor. The developed detectors and electronics are now ready for the production, which will last for the next 2 years.
    Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment 08/2013; · 1.14 Impact Factor
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    ABSTRACT: A unique compact LINAC accelerator for proton therapy is under development in Italy within the TOP-IMPLART project. The proton beam will reach the kinetic energy of 230 MeV, it will have a widely variable current intensity (0.1–10 μA, with average up to 3.5 nA) associated with a high pulse repetition frequency (1–3.5 μs long pulses at 10–100 Hz). The TOP-IMPLART system will provide a fully active 3+1D dose delivery, that is longitudinal (energy modulation), transverse active spot scanning, and current intensity modulation. These accelerator features will permit a highly conformational dose distribution, which therefore requires an effective, online, beam monitor system with wide dynamic range, good sensitivity, adequate spatial resolution and rapid response. In order to fulfill these requisites a new device is under development for the monitoring of the beam intensity profile, its centroid and direction; it is based on transmission, segmented, ionization chambers with typical active area of 100 × 100 mm2. Micro pattern x/y pad like design has been used for the readout plane in order to maximize the field uniformity, reduce the chamber thickness and obtain both beam coordinates on a single chamber. The chamber prototype operates in ionization region to minimize saturation and discharge effects. Simulations (based on FLUKA) have been carried on to study the perturbation of the chamber on the beam parameters and the effects on the delivered dose (on a water phantom). The charge collected in each channel is integrated by dedicated auto-ranging readout electronics: an original scheme has been developed in order to have an input dynamic range greater than 104 with sensitivity better than 3%. This is achieved by a dynamical adjustment of the integrating capacitance to the signal intensity.
    Journal of Instrumentation 03/2012; 7(03):C03020. · 1.66 Impact Factor
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    ABSTRACT: A new proton therapy center is planned to be built in Rome, Italy. The project, named TOP-IMPLART, is developed by three institutions, ENEA (Agenzia Nazionale per le Nuove tecnologie, l’Energia e lo Sviluppo Economico Sostenibile - Italian national agency for new technologies, energy and sustainable economic development), ISS (Istituto Superiore di Sanità, Italian National Institute of Health) and IFO-IRE (Istituto Fisioterapico Ospedaliero - Istituto Regina Elena, Regina Elena, National Cancer Institute in Rome). The project is centered on a medium-energy proton accelerator designed as a sequence of linear accelerators. Two phases of construction are foreseen: the first (funded by the Italian Regione Lazio for 11 M€ spread over four years) with a maximum energy of 150 MeV and the second one up to 230 MeV. The segment up to 150 MeV is under construction and will be tested at the ENEA Research Center in Frascati before the transfer to IFO that is the clinical user. The basic concepts of the design are described here.
    European Physical Journal Plus 01/2011; 126(7):1-15. · 1.30 Impact Factor
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    ABSTRACT: A new proton beam monitoring system and its dedicated electronics is under development for the TOP-IMPLART proton therapy facility, based on 10 to 100 Hz pulsed proton LINAC, with maximum kinetic energy of 230 MeV. The system consists of segmented ionization chambers that will measure the beam intensity profile, position and direction to monitor the fully active 3+1D beam. The chamber readout electronics, based on multiplexed multichannel sample and hold, dynamically adapts the integration capacitance on each of its input trans-impedance amplifier to the incoming charge, reaching a rather challenging dynamic range larger than 104 and relative sensitivity better than 3%.
    01/2011;