V. P. Antonovich

Publications (3)2.24 Total impact

• Article: Determination of medicinal preparations, salts of organic bases, by the effect of their anions on the luminescence of lanthanide complexes

  D. I. Alekscandrova, A. V. Egorova, Yu. V. Skripinets, V. P. Antonovich, I. V. Ukrainets
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  ABSTRACT: The luminescence parameters of Eu(III) and Tb(III) complexes with fluorinated amide derivatives of hydroxyquinoline carboxylic acid (L1–8) were studied. It was shown that medicinal preparations, salts of organic bases, can be determined from the effect of their anions on the luminescence of Eu(III)-sensitizing ligand complexes. The Eu(III)-L1-citrate ion and Eu(III)-L2-tartrate ion complexes were proposed for the luminescence determination of clomiphene and tamoxifen citrates and platyphyllin tartrate, respectively. The detection limits were 0.30 μg/mL for clomifene (tamoxifen) citrate and 0.85 μg/mL for platyphyllin tartrate.
  Journal of Analytical Chemistry 04/2012; 64(7):705-713. · 0.75 Impact Factor
• Article: Luminescence determination of DNA using terbium complexes with 2-oxo-4-hydroxyquinoline-3-carboxylic acid amides as probes

  Yu. V. Skripinets, A. V. Egorova, I. V. Ukrainets, V. P. Antonovich
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  ABSTRACT: It was found that the presence of DNA significantly enhanced the 4f luminescence of terbium(III) in its complexes with a number of 2-oxo-4-hydroxyquinoline-3-carboxylic acid amide derivatives (L1-L6). For the high-sensitivity determination of DNA, L1 and L4 were chosen from two proposed groups, in complexes with which terbium ions exhibited the most intense luminescence. Under optimum conditions, the luminescence intensity of terbium was proportional to the concentration of DNA over the ranges 0.025–1.2 μg/mL (detection limit of 10 ng/mL) and 0.01–1.2 λg/mL (detection limit of 3 ng/mL) for L1 and L4, respectively. The mechanisms of the interaction of Tb-L complexes with DNA molecules were hypothesized.
  Journal of Analytical Chemistry 12/2005; 61(1):44-51. · 0.75 Impact Factor
• Article: Relationship between the analytical properties of lanthanide(III) βdiketonates and the nature of ligands

  S. B. Meshkova, V. E. Kuz’min, Yu. E. Shapiro, Z. M. Topilova, I. V. Yudanova, D. V. Bol’shoi, V. P. Antonovich
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  ABSTRACT: The effect of the nature of β-diketones on the spectrochemical-luminescence properties of lanthanide complexes used as analytical forms for the highly sensitive determination of some rare-earth elements was examined. NMR spectroscopy, molecular mechanics, calculations, and an experimental evaluation of the hydrophobicity of the test β-diketones indicated that an increase in the intensity, quantum yield, and lifetime of luminescence of lanthanide (Ln) β-diketonates depends on the charge distribution in the chelate ring, on the spatial structure, and on the hydrophobicity of the coordinated ligand. These factors determine the efficiency of energy transfer from the β-diketone to the Ln+3 ion and the decrease in energy losses caused by the quenching action of water molecules.
  Journal of Analytical Chemistry 01/2000; 55(2):102-108. · 0.75 Impact Factor