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Publications (9)2.75 Total impact

  • Southern Medical Journal 01/1953; 46(5):428-433. · 0.92 Impact Factor
  • GORDON McHARDY, DONOVAN C. BROWNE
    Southern Medical Journal 09/1943; 36(10):674-676. · 0.92 Impact Factor
  • Donovan C. Browne, Gordon Mchardy
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    ABSTRACT: Conclusions (1) We are inclined to accept an organic background for cascading because of our findings in this and in two previous incidents. (2) Gastroscopy was not of material aid in the diagnosis. (3) Assuming that a goodly number of Cascade Stomachs are of organic origin, should conservative measure fail, exploratory laparotomy should exclude organic pathology to permit a diagnosis of spasmodic Cascade Stomach. We are indebted to Dr. M. Teitelbaum for his cooperation in roentgenologic study.
    Digestive Diseases and Sciences - DIGEST DIS SCI. 01/1943; 10(6):224-226.
  • DONOVAN C. BROWNE, GORDON McHARDY
    Southern Medical Journal 11/1941; 34(12):1257-1259. · 0.92 Impact Factor
  • DONOVAN C. BROWNE, GORDON McHARDY
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    ABSTRACT: In 150,952 privately studied hospital admissions at Touro Infirmary (1926-1939) including 1,810 autopsies and 1,010,711 (1906-1939) cases at Charity Hospital of New Orleans with 6,160 (1936-1939) postmortem observations, primary pathologic changes of the jejunum were illustrated in a single instance each of traumatic regional enteritis and of intussusception, sixteen cases of diverticula, four perforated ulcers and eleven neoplastic involvements, of which seven were benign and four malignant.This survey indicates an almost inconceivably low incidence. Yet the publications of recent years show increased cognizance of lesions of the small intestine. The number of case reports suggests either an increased incidence, the trend to report unusual pathologic conditions or diagnostic acumen. A study of the individual cases, however, reveals that only obvious lesions have been diagnosed by the clinician and roentgenologist. In many instances the establishment of the diagnosis came as a surprise to the exploring surgeon; most awaited necropsy study.
    Journal of the American Medical Association 115(26):2257-2263.
  • Gordon McHardy, Donovan C. Browne
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    ABSTRACT: Identical or uniovular twins theoretically contain "identical determiners" in their chromosomes which constitute the chief physical basis of heredity; they are always of the same sex and of similar physical characteristics. They are therefore often of equally normal mental and physical pattern; likewise pathologic departures of close contrast, in both respects, are not unusual. Depiction of the spiritual communion manifest between twins has produced interesting reading; the Antipholus pair served by the Dromio identicals gave us Shakespeare's "Comedy of Errors." Numerous less prominent literatures and fictional authors have used the similarity to advantage.Medical writers have interested themselves in the physiology of twinning and the study of twins in health and disease. Perusal of reference sources reveals case reports of diverse and seemingly innumerable pathologic entities common to identical twins. This survey, however, fails to produce a reported instance of a duodenal ulcer occurring in one or both of identical
    Journal of the American Medical Association 124(8):503-503.
  • Donovan C. Browne, Gordon Mchardy, Carl Wilen
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    ABSTRACT: 1. Our autopsy findings adhere closely to those of the literature. 2. Experimentally: (A) Acidity and stasis had no significance. (B) The fundal and cardiac pouches were not susceptible. (C) The pyloric pouch was susceptible to two methods of introduction. (D) The submucosal and hematogenous routes were the only successful methods of exciting a significant mucosal change. 3. Gastroscopically: (A) Normal mucosa represented 34.7 per cent. (B) Atrophic and superficial gastritis were of equal incidence. (C) Ulcers were more frequent than in routine gastroscopies. (D) No gastritis of pathognomonic significance was established. (E) Of the lesions we classified atypical, two were suggestive of tuberculosis. 4. Our work leads us to expect that the continuation of this experimentation will permit us to produce and endoscopically observe development of mucosal changes of tuberculosis and that thereby we may gastroscopically identify the same lesions in the human. We should like to express our appreciation to Drs. T. Tilghman Herring and Reynold Pagzer who performed the surgical procedures
    The American Journal of Digestive Diseases 9(12):407-411.
  • Donovan C. Browne, Gordon McHardy
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    ABSTRACT: 1. 1. We herewith add six illustrative case reports of acute intestinal obstruction due to cecal volvulus to the limited literature We herewith add six illustrative case reports of acute intestinal obstruction due to cecal volvulus to the limited literature on the subject. Three of our cases were post-operative equaling the total published instances encountered in our review of on the subject. Three of our cases were post-operative equaling the total published instances encountered in our review of the literature. Our statistical study reveals an incidence of only 1.4 per cent among 411 cases of acute intestinal obstruction. the literature. Our statistical study reveals an incidence of only 1.4 per cent among 411 cases of acute intestinal obstruction. 2. 2. A clinical diagnosis of acute cecal volvulus is seldom made since there are no diagnostic criteria that render a clinical A clinical diagnosis of acute cecal volvulus is seldom made since there are no diagnostic criteria that render a clinical diagnosis feasible. However, cecal volvulus must be considered in making a diagnosis in obscure cases of intestinal obstruction. diagnosis feasible. However, cecal volvulus must be considered in making a diagnosis in obscure cases of intestinal obstruction. 3. 3. Chronic cecal volvulus is an entity rarely encountered and probably overlooked in many instances of unexplained abdominal Chronic cecal volvulus is an entity rarely encountered and probably overlooked in many instances of unexplained abdominal pain. pain.
    The American Journal of Digestive Diseases 9(5):177-180.
  • Donovan C. Browne, Gordon McHardy
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    ABSTRACT: 1. Conservative medical therapy is the procedure of choice in treating bleeding ulcers. 2. Reservation should be practiced in accepting Meulengracht’s immediate feeding of patients with active bleeding. 3. Aluminum hydroxide offers an approach to attaining physiological control of a bleeding ulcer. It has a favorable place in our case report. 4. Transfusions by the direct method can be given safely without worry over elevated venous pressure, arterial pressure or any systemic reaction of significance. 5. Vitamins have an undetermined position in bleeding ulcer therapy. 6. We would not feed our bleeding ulcer cases immediately but would institute continuous aluminum hydroxide drip, a dietary regimen to be started when hemorrhage had ceased and sufficient time had elapsed for clot fibrosis. We feel that parenteral fluids should be given freely to maintain nutrition, water balance, circulating volume and to combat acidosis. Until proven otherwise synthetic Vitamin C will be considered a valuable adjunct to our regimen.
    The American Journal of Digestive Diseases 6(2):87-92.