Publications (1)0.73 Total impact
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Article: Novel synthesis and cytotoxic activity of some chromeno[3,4-b]pyrrol-4(3H)-ones
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ABSTRACT: 1-Methylchromeno[3,4-b]pyrrol-4(3H)-one and 1-phenylchromeno[3,4-b]pyrrol-4(3H)-one derivatives have been synthesized by cyclization of amides obtained by condensing α-halo ketones with 3-amino-chromenones, which show cytotoxic activity against lung, colon, and breast cancer cell lines. Keywordsbenzopyrones–halo ketones–chromeno[3,4-b]pyrrol-4(3H)-ones–cytotoxic agentsChemistry of Heterocyclic Compounds 04/2012; 46(12):1514-1519. · 0.73 Impact Factor