Shaoming Fang

Zhengzhou University of Light Industry, Cheng, Henan Sheng, China

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Publications (24)45.56 Total impact

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    ABSTRACT: In this paper, we report on the facile one-step synthesis of nanoporous cuprous oxide microspheres on reduced graphene oxide (Cu2OMS-rGO) by synchronously reducing Cu2+ ions and GO with ascorbic acid sodium, followed by their application as electrochemical biosensors for the detection of mercury ions in water. After detailed characterizations of the basic chemical components, crystal structure, surface morphology, and electrochemical properties of the Cu2OMS-rGO nanocomposites, single-stranded and thymine (T)-rich oligonucleotides were successively immobilized onto the surface of the composite electrode modified by Cu2OMS-rGO. Upon introduction of the target analyte, Hg2+ ions were intercalated into the DNA polyion complex membrane based on T-Hg2+-T coordination chemistry. The results show that the Cu2OMS-rGO composite has high sensitivity for the detection of Hg2+, with a detection limit of 8.62 pM within the range of 0.05 nM to 40 nM. Therefore, the Cu2OMS-rGO composite could be utilized as a novel biosensor for the detection of heavy metal ions in water or in the environment. The strategy yielded excellent selectivity of Hg2+ against other interfering metal ions. In addition, the developed DNA sensor for the determination of Hg2+ ions could be reproduced up to 10 cycles, and the recovery was approximately 95%.
    New Journal of Chemistry 09/2014; · 3.16 Impact Factor
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    ABSTRACT: The morphological control of mesoporous silica without any additives has attracted much attention. Discrete rod-like and string-of-beads like mesoporous SBA-15 can be achieved under ultrasound irradiation without changing the composition of synthesis system. The smaller particles of SBA-15 showed improved lysozyme immobilization capacity and higher adsorption rate over conventional rope-like SBA-15.
    Ultrasonics Sonochemistry 08/2014; · 3.52 Impact Factor
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    ABSTRACT: A quaternary nanocomposite Fe3O4@SiO2@TiO2/graphene oxide (GO) was for the first time successfully synthesized in this work for the repeated use in simultaneous adsorption and photocatalytic degradation of aromatically structured chemical pollutants. The resulting sample was characterized by TEM, XRD, FTIR, TG-DTG, XPS, PL, and VSM. Its photocatalytic activity was evaluated in the photocatalytic degradation of rhodamine B (RhB) under high-pressure mercury lamp irradiation. The results showed that about 63% of RhB was absorbed onto the prepared Fe3O4@SiO2@TiO2/GO nanocomposites by just 30 minute mixing, and after 120 min high-pressure mercury lamp irradiation, about 92.03% of RhB was converted. The photocatalytic degradation followed pseudo first-order reaction with an apparent rate constant of 0.0136 min(-1). Compared with the Fe3O4@SiO2@TiO2 nanoparticles, it exhibits an excellent ability to adsorb aromatic compounds via π-π stacking and a higher photocatalytic activity due to the presence of GO. In addition, the synthesized nanomaterial exhibited good magnetic response and the reusability study suggested that the prepared nanocomposites were stable enough and maintained high degradation rate and catalyst recovery even after five cycles, verifying their potential application in water purification.
    Dalton Transactions 08/2014; · 4.10 Impact Factor
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    ABSTRACT: Imine-linked covalent organic framework on amino functionalized silicon substrate was constructed via a step-wise reaction between 1,3,5-benzenetricarboxaldehyde and 1,4-diaminobenzene. The obtained material was used as biosensor for bovine serum albumin (BSA) adsorption and probe DNA immobilization, which extended the application of covalent organic frameworks (COFs) to a new field.
    Chinese Journal of Chemistry 07/2014; · 0.92 Impact Factor
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    ABSTRACT: In this study, octavinyl polyhedral oligomeric silsesquioxane (OVPS) is used as the cross-linker instead of N, N’-methylenebisacrylamide (BIS) to copolymerize with 2-(dimethylamino) ethyl methacrylate (DMAEMA) or DMAEMA and N-isopropylacrylamide (NIPAM) to prepare hybrid hydrogels: P(OVPS-co-DMAEMA) and P(OVPS-co-DMAEMA-co- NIPAM). The prepared hydrogels are transparent and show dual response to temperature and pH. The hydrogels are characterized by FT-IR, SEM, XRD, DSC, TGA, DMA and tensile tests. Their mechanical properties, swelling ratio, deswelling, reswelling behaviors as well as drug release properties were investigated. The results indicate that OVPS can be incorporated into polymer networks in proportion to feed ratios. P(OVPS-co-DMAEMA) hydrogel exhibits more homogenous interior structure, higher swelling ratio and faster response than the conventional hydrogel prepared with BIS. Moreover, the incorporation of OVPS enhances the compression and tensile properties of the hydrogels. The feed ratios of OVPS and NIPAM greatly effect on volume phase transition temperature (VPTT), thermal-sensitivity, swelling behavior, mechanical property and drug release property of the hybrid hydrogels. The prepared dual responsive POSS-containing hydrogels are expected to be used as biomedical materials in drug release and tissue engineering.
    Polymer International 04/2014; · 2.13 Impact Factor
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    ABSTRACT: A label-free and effective aptasensor based on an amino-functionalized nanocomposite of graphene and plasma-polymerized allylamine (G–PPAA) was developed for thrombin detection. Graphene was assembled on the substrate, followed by the self-assembly of octadecylamine (OTA) to protect the graphene from etching by subsequent plasma irradiation. Afterward, PPAA was deposited onto the graphene surface with the self-assembled OTA, and the nanocomposite with amino groups was fabricated. The label-free thrombin aptamer was immobilized onto the amino-functionalized nanocomposite matrix via electrostatic interaction between the phosphate groups of the aptamer and the amino groups in PPAA. The process was investigated using impedimetric detection and a quartz crystal microbalance (QCM). The chemical compositions, surface morphology, and electrochemical properties were found to be dependent on the plasma conditions used in the polymer deposition. The amounts and kinetics of aptamer immobilization and thrombin detection were determined using QCM measurements. A relatively high affinity constant of aptamer immobilization and low detection limit for thrombin were achieved by using the G–PPAA film as the biosensor matrix. Results suggest that G–PPAA films can be applied in gene therapy and protein detection.
    J. Mater. Chem. B. 02/2014; 2(11).
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    ABSTRACT: This study investigates the application of Plasma-polymerized pyrrole (ppPY) as bioactive platform for DNA immobilization and cell adhesion based on the fundamental properties of ppPY, such as chemical structure, electrochemical property, and protein adsorption. Variations in electrochemical properties of the ppPY film deposited under different plasma conditions before and after DNA immobilization were measured using electrochemical impedance spectroscopy (EIS). The equilibrium concentration of the probe DNA immobilized on the ppPY surface was deduced by detecting the variations in the surface charge transfer resistance (Rct ) of the ppPY films after DNA immobilization with different concentrations. In addition, the detection limit of the target DNA hybridization with probe DNA, the association constant, Ka , and the dissociation constant were deduced from Langmuir isotherm equations simulated using the experimental data collected by EIS. Moreover, inverted microscope was used to observe the cell adhesions onto the surface of the ppPY films prepared under different plasma conditions. Different adhesive behaviors of cells were observed, demonstrating that ppPY films could be an alternative biomaterial used as the sensitive layer for DNA sensor or cell adhesion.
    Biopolymers 10/2013; · 2.88 Impact Factor
  • Lijun Gao, Liming Zhou, Shaoming Fang, Chao Wu
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    ABSTRACT: A series of new crosslinked copoly(urethane-methacrylate)s (CPUAs) were synthesized by the polymerization of new urethane–methacrylate macromonomers with double bonds at the end of the chain, which were prepared from isophorone diisocyanate, β-hydroxyethyl methacrylate, different content of poly(1,2-propanediol ortho-phthalate) (PPP), and poly(ethylene glycol) 600. The properties of CPUAs were measured by dynamic mechanical analysis, thermogravimetric analysis, wide-angle X-ray diffraction, water uptake, and optical properties testing, and mechanical performance measurements. The results revealed that the greater PPP contents in the CPUAs lead to the higher glass transition temperature, hardness, lower thermal stability, and water uptake. Obtained CPUAs present the good transparence. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
    Journal of Applied Polymer Science 06/2013; 128(6). · 1.40 Impact Factor
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    ABSTRACT: Well-dispersed multiwalled carbon nanotubes/polyurethane (MWCNTs/PU) composites were synthesized in situ polymerization based on treating MWCNTs with nitric acid and silane coupling agent. The morphology and degree of dispersion of the MWCNTs were studied using a high resolution transmission electron microscopy (HR-TEM) and X-ray powder diffraction (XRD). The result showed that MWCNTs could be dispersed still in the PU matrix well with the addition of 2 wt% MWCNTs. The thermal and mechanical properties of the composites were characterized by dynamic mechanical thermal analysis, thermogravimetric analysis, tensile, and impact testing. The result suggested that the glass transition temperature (Tg) of composites increased greatly with increasing MWCNTs content slightly, and the MWCNTs is also helpful to improve mechanical properties of composites. Furthermore, the composites have an excellent mechanical property with the addition of 0.5 wt% MWCNTs. The electrical property testing indicates that the MWCNTs can improve evidently the electrical properties of composites when adding 1 wt% MWCNTs to the PU matrix. The volume resistivity of composites reaches to an equilibrium value. POLYM. COMPOS., 33:1866–1873, 2012. © 2012 Society of Plastics Engineers
    Polymer Composites 11/2012; 33(11). · 1.48 Impact Factor
  • Rui Wang, Shaoming Fang, Lijun Gao, Liming Zhou
    Journal of Computational and Theoretical Nanoscience, vol. 9, issue 9, pp. 1264-1268. 09/2012; 9(9):1264-1268.
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    ABSTRACT: In order to exploit the applications of polypyrrole (PPy) derivatives in biosensors and bioelectronics, the different immobilization mechanisms of biomolecules onto differently functionalized conducting PPy films are investigated. Pyrrole and pyrrole derivatives with carboxyl and amino groups were copolymerized with ω-(N-pyrrolyl)-octylthiol self-assembled on Au surface by the method of the chemical polymerization to form a layer of the copolymer film, i.e., poly[pyrrole-co-(N-pyrrolyl)-caproic acid] (poly(Py-co-PyCA)) and poly[pyrrole-co-(N-pyrrolyl)-hexylamine] (poly(Py-co-PyHA)), in which the carboxyl groups in poly(Py-co-PyCA) were activated to the ester groups. Based on the structure characteristics, the immobilization/hybridization of DNA molecules on PPy, poly(Py-co-PyCA) and poly(Py-co-PyHA) were surveyed by cyclic voltammograms measurements. For differently functionalized copolymers, the immobilization mechanisms of DNA are various. Besides the electrochemical properties of the composite electrodes of PPy and its copolymers being detected before and after bovine serum albumin (BSA) adsorption, the kinetic process of protein binding was determined by surface plasmon resonance of spectroscopy. Since few BSA molecules could anchor onto the PPy and its copolymers surfaces, it suggests this kind of conducting polymers can be applied as the protein-resistant material.
    Chinese Journal of Chemistry 02/2012; 30(2). · 0.92 Impact Factor
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    ABSTRACT: In this paper, polyhedral oligomeric silsesquioxanes (POSS) with three different substituents are blended with poly(L-lactic acid) (PLLA) solution to prepare the hybrid films. The three types of POSS are octa(3-chloroammoniumpropyl)silsesquioxane (OCAPS), octa(3-chloropropyl)silsesquioxane (OCPS) and octavinylsilsesquioxane (OVPS). The effects of POSS substituents on the dispersion and properties of PLLA are investigated by means of SEM, XRD, DSC, DMA, POM, TGA, tensile and in vitro tests. The results show that OCAPS and OCPS have better dispersion states than OVPS, supported by the fact that an obvious phase separation is observed in OVPS/PLLA hybrid film. OCAPS and OVPS hybrid materials show higher Tgs than that of PLLA, whereas OCPS acts as a plasticizer to decrease the Tg of PLLA. Meanwhile, the Tms of PLLA are all decreased by the incorporation of the three POSS. The thermal stability of PLLA has been improved by the presence of OCPS and OVPS. The addition of POSS does not change the crystalline structure of PLLA and POSS appears as the heterogeneous nucleating agents in PLLA matrix, as the Tcs of POSS/PLLA in the reheating cycles shift to lower temperatures. The elongations at break point of OCAPS and OCPS hybrid films increase due to their plasticizer effect when the mechanical force is put on. The hydrophobic character of OCPS and OVPS prohibits the degradation of PLLA, however, OCAPS/PLLA shows faster degradation rate than PLLA due to the high hydrophilic property of OCAPS.
    Journal of Macromolecular Science Part A 01/2012; 49(1):73-80. · 0.81 Impact Factor
  • Plasma Processes and Polymers 10/2011; 8(10). · 3.73 Impact Factor
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    ABSTRACT: This work is directed towards the synthesis of multifunctional nanoparticles composed of Fe(3)O(4)-Au nanocomposite cores and a porous silica shell (Fe(3)O(4)-Au/pSiO(2)), aimed at ensuring the stability, magnetic, and optical properties of magnetic-gold nanocomposite simultaneously. The prepared Fe(3)O(4)-Au/pSiO(2) core/shell nanoparticles are characterized by means of TEM, N(2) adsorption-desorption isotherms, FTIR, XRD, UV-vis, and VSM. Meanwhile, as an example of the applications, catalytic activity of the porous silica shell-encapsulated Fe(3)O(4)-Au nanoparticles is investigated by choosing a model reaction, reduction of o-nitroaniline to benzenediamine by NaBH(4). Due to the existence of porous silica shells, the reaction with Fe(3)O(4)-Au/pSiO(2) core/shell nanoparticles as a catalyst follows second-order kinetics with the rate constant (k) of about 0.0165 l mol(-1) s(-1), remarkably different from the first-order kinetics with the k of about 0.002 s(-1) for the reduction reaction with the core Fe(3)O(4)-Au nanoparticles as a catalyst.
    Dalton Transactions 06/2011; 40(41):10857-64. · 4.10 Impact Factor
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    ABSTRACT: A series of organic-inorganic hybrid films were prepared based on octa(3-chloropropylsilsesquioxane) (OCPS) and poly(L-lactic acid) (PLLA) via simply solution blending method. The thermal, crystalline and mechanical properties of OCPS/PLLA hybrid films were characterized by Fourier transform infrared, scanning electron microscopy, energy dispersive spectrometer, differential scanning calorimetry (DSC), X-ray diffraction, polarized optical microscopy, thermogravimetric analysis (TGA), and tensile tests. The results showed that OCPS could be dispersed well at molecular level when its content was less than 3 wt % and began to crystallize in PLLA matrix when the content increased to 5 wt %. DSC study revealed that OCPS acted as a plasticizer to decrease both Tg and Tm of the PLLA matrix at various heating rates. The addition of OCPS did not change the crystal form of PLLA, while had an great influence on the cold crystallization and melting behaviors of PLLA in the second heating cycles. Moreover, the initial crystallinity of OCPS/PLLA was higher than that of pure PLLA. The results suggested that OCPS could be an effective heterogeneous nucleating reagent to promote the crystallization of PLLA. TGA showed that the PLLA thermal degradation mechanism remained unchanged, whereas the weight loss temperatures and residual weights were improved. Tensile tests indicated that the incorporation of OCPS into PLLA matrix changed the tensile behavior of the hybrid films from brittle to ductile, and the strain at break was improved remarkably as a result of the plasticizer effect of OCPS. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
    Journal of Applied Polymer Science 04/2011; 122(1):296 - 303. · 1.40 Impact Factor
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    ABSTRACT: In order to fabricate a new polymer matrix for application in biochips and to understand the mechanism of adsorption of proteins on conducting polymers, we prepared polypyrrole (PPy) functionalized with ‐(N‐pyrrolyl)‐octylthiol moieties. The chemical structure of the polymer could be controlled by varying the concentration of pyrrole added as the monomer. Initially, ‐(N‐pyrrolyl)‐octylthiol was self‐assembled into a monolayer on a gold surface. Thereafter, a layer of uniform and smooth PPy was obtained by the chemical copolymerization of pyrrole and the ‐(N‐pyrrolyl)‐octylthiol. Bovine serum albumin (BSA) adsorption on the polymer was investigated using surface plasmon resonance spectroscopy and cyclic voltammograms. The chemical structure and monomer components of the as‐prepared films were characterized using Fourier transform infrared spectroscopy and X‐ray photoelectron spectroscopy. Water contact angle measurements were used to assess the surface wettability of the films throughout the preparative procedure. The kinetics of BSA adsorption onto the polymer could be controlled by varying the copolymer thickness and the pH value of the buffer solutions used. Moreover, the electroactivity was changed upon BSA binding. The results suggest that the new conducting polymer may potentially be applied as a more sensitive and reliable matrix in protein sensors. Copyright © 2011 Society of Chemical Industry
    Polymer International 01/2011; 60(4):703 - 710. · 2.13 Impact Factor
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    ABSTRACT: A pair of novel TbIII-based enantiomers, [Tb(dbm)3·LSS] (1) and [Tb(dbm)3·LRR] (2) (where LSS=(+)-4,5-pinene bipyridine, LRR= (-)-4,5-pinene bipyridine, dbm=dibenzoylmethanate), were synthesized and characterized based on single crystal X-ray diffraction, elemental analysis, FT-IR, TG and CD spectra. X-ray diffraction analysis showed that both the complexes crystallized in monoclinic crystal system with P21 chiral space group. The TbIII ion was eight-coordinated by six O atoms of three dbm ligands and two N atoms from one chiral ligand LSS or LRR. The CD spectra revealed that complexes 1 and 2 were enantiomers. Thermogravimetric analysis results indicated that 1 and 2 were thermally stable up to 246 °C.
    Journal of Rare Earths 01/2011; 29(1):28-31. · 1.36 Impact Factor
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    ABSTRACT: A series of novel cross-linked poly (urethane-methacrylate)s (PUAs) were synthesized in a three-step process: Four kinds of low number average molecular weight aromatic polyesters (PEs) with terminal hydroxyl groups were obtained by phthalic anhydride (PA) reacted with 1,2-propanediol (PDO), 1,4-butanediol (BDO), 1,6-hexanediol (HDO), and diethylene glycol (DEG), respectively. Then, a series of urethane-methacrylate macromonomers(UMAs), which have double bonds at the end of the chain, were prepared from isophorone diisocyanate (IPDI), the PEs obtained in first step, poly(ethylene glycol) 600 (PEG600) and ß-hydroxyethyl methacrylate(HEMA). Dibutytin dilaurate (DBTL) was used as catalyst. Finally, a series of thermosetting PUAs were synthesized by the polymerization of novel functional UMAs using 2,2'-azobis(isobutyronitrile) (AIBN) as catalyst. The compositions of the PEs and UMAs were determined by 1H-NMR and fourier transform infrared (FT-IR). The properties of PUAs were measured by dynamic mechanical analysis (DMA), thermogravimetric analysis (TGA), wide-angle X-ray diffraction (WAXD), water uptake and optical properties testing, and mechanical performance measurements. The results revealed that the mechanical and degradation properties of PUAs were influenced by the kinds of PE or polyether polyols in the PUAs remarkably. The obtained PUAs present the good thermal and mechanical properties, low water uptake (below 1%) and high transparence (above 90%). The diversity of properties suggests that these PUAs can be used in a wide range of excellent optical polymer applications.
    Journal of Polymer Research 01/2011; 18(4). · 2.02 Impact Factor
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    ABSTRACT: In order to fabricate a soluble conducting polypyrrole matrix, applied as a biomaterial to anchor proteins, the preparation of a poly(acryoyl pyrrole)-g-polypyrrole (PAP-g-PPy) copolymer and the adsorption of bovine serum albumin (BSA) onto this conducting copolymer were studied. Polypyrrole (PPy) was synthesized by electrochemical polymerization on an Au surface, which had been spin-coated with a poly(acryloyl chloride) precursor containing a pyrrole moiety in its side chain. The chemical properties of PPy depend on the polymerization conditions, i.e., the concentration of pyrrole and the polymerization time. Subsequently, the adsorption behavior of BSA on PAP-g-PPy was investigated by surface plasmon resonance spectroscopy, suggesting that the copolymer thickness, the concentration of pyrrole monomer used in the preparation of the polymer, the BSA concentration and the pH value of buffer solutions can affect the adsorption behavior of BSA onto the polymer surface. It is therefore predicted that the conducting copolymer PAP-g-PPy could be used as an adsorbed matrix for protein adsorption.
    New Journal of Chemistry 01/2010; · 3.16 Impact Factor
  • Acta Polymerica Sinica - ACTA POLYM SIN. 01/2010; 010(8):1023-1029.