Kimberly A Fleming

Publications (2)4.19 Total impact

• Article: Alcohol Cues, Approach Bias, and Inhibitory Control: Applying a Dual Process Model of Addiction to Alcohol Sensitivity.

  Kimberly A Fleming, Bruce D Bartholow
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  ABSTRACT: Low sensitivity to the acute effects of alcohol is a risk factor for heavy drinking and related problems. However, little research has tested process explanations for such effects. The current study tested the hypothesis that low sensitivity is associated with automatic approach biases for alcohol cues, coupled with deficits inhibiting responses in the presence of such cues. Eighty-five participants varying in alcohol sensitivity completed an Alcohol-Approach Avoidance Task and a Cued Go/No-Go Task while event-related potentials were recorded. Low sensitivity (LS) individuals showed evidence of automatic approach tendencies toward alcohol cues in both tasks, and experienced deficits inhibiting prepotent responses cued by alcohol images. Additionally, the event-related potential data indicated that LS individuals experienced more conflict when attempting to inhibit alcohol-cued responses, but not nonalcohol-cued responses, compared with their high-sensitivity counterparts. Together, these data indicate that alcohol cues elicit an approach bias among LS individuals, translating into greater difficulty inhibiting behavioral responses in the presence of such cues, a pattern generally supportive of dual process models of substance use. (PsycINFO Database Record (c) 2013 APA, all rights reserved).
  Psychology of Addictive Behaviors 02/2013; · 2.09 Impact Factor
• Article: Effects of Alcohol on Sequential Information Processing: Evidence for Temporal Myopia.

  Kimberly A Fleming, Bruce D Bartholow, Jeffrey Sable, Melanie Pearson, Monica Fabiani, Gabriele Gratton
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  ABSTRACT: Alcohol Myopia Theory (AMT) posits that alcohol restricts the focus of attention, such that behaviors are determined only by highly salient environmental cues. While AMT is most commonly understood in terms of spatial attention, the present study tested the effects of alcohol in the temporal domain of attention. Seventy-one participants consumed either a placebo beverage or one of two doses of alcohol (0.40g/kg or 0.80g/kg ETOH) before performing an auditory discrimination task while event-related potentials (ERPs) were recorded. Consistent with typical sequential effects, placebo participants showed increased P300 amplitude and slowed behavioral responses when the current target differed from the two-back tone. In contrast, alcohol caused increased P300 and response slowing when the target tone differed from the one-back tone. These findings suggest that alcohol increases the salience of more recently encountered information, consistent with the general tenets of AMT. (PsycINFO Database Record (c) 2012 APA, all rights reserved).
  Psychology of Addictive Behaviors 05/2012; · 2.09 Impact Factor