W Müller-Forell

Universitätsklinikum Freiburg, Freiburg an der Elbe, Lower Saxony, Germany

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Publications (67)113.54 Total impact

  • T. Ibis · J. Gawehn · F. Thoemke · W. Mueller-Forell · M. Dieterich · C. Best ·

    Joint Congress of European Neurology; 05/2014
  • C. Best · P. Zu Eulenburg · H. H. Kraemer · T. Bauermann · W. Mueller-Forell · M. Dieterich ·

    Joint Congress of European Neurology; 05/2014
  • S. Welschehold · T. Kerz · S. Boor · A. Reuland · W. Mueller-Forell ·

    Journal of the Neurological Sciences 10/2013; 333:e281-e282. DOI:10.1016/j.jns.2013.07.1068 · 2.47 Impact Factor
  • S Welschehold · T Kerz · S Boor · K Reuland · F Thömke · A Reuland · C Beyer · W Wagner · W Müller-Forell · A Giese ·
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    ABSTRACT: Background and purpose: Computed tomographic-angiography (CT-A) is becoming more accepted in detecting intracranial circulatory arrest in brain death (BD). An international consensus about the use and the parameters of this technique is currently not established. We examined intracranial contrast enhancement in CT-A after clinically confirmed BD, compared the results with electroencephalography (EEG) and Transcranial Doppler Ultrasonography (TCD) findings and developed a commonly applicable CT-A protocol. Methods: Prospective, monocentric study between April 2008 and October 2011. EEG, TCD and CT-A were performed in 63 patients aged between 18 and 88 years (mean, 55 years) who fulfilled clinical criteria of BD. Evaluation of opacification of cerebral vascular territories in CT-A was performed in arterial as well as in venous scanning series by a neuroradiologist and a neurointensivist/neurosurgeon together. Results: CT-A demonstrated a 95% sensitivity in detecting intracranial circulatory arrest when analysing arterial scanning series. We never observed venous blood return in internal cerebral veins. In three cases, BD confirmation by EEG failed because of artefacts. Confirmation of BD by TCD failed in two cases because of absent temporal window. In three cases, TCD demonstrated residual blood flow. Conclusion: CT-A is easily accessible in almost every hospital, offers a high spatio-temporal resolution, is operator independent and inexpensive. The results of CT-A are comparable to other established brain perfusion techniques in BD. An international consensus should be established to ascertain consistent parameters similar to fixed guidelines for other ancillary procedures to determine BD in order to prevent different scanning and evaluation protocols for detecting intracranial circulatory arrest.
    European Journal of Neurology 07/2012; 20(1). DOI:10.1111/j.1468-1331.2012.03826.x · 4.06 Impact Factor
  • Wibke Müller-Forell · George J Kahaly ·
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    ABSTRACT: Neuroimaging of Graves' orbitopathy (GO) plays an important role in the differential diagnosis and interdisciplinary management of patients with GO. Orbital imaging is required in unclear or asymmetric proptosis, in suspected optic neuropathy and prior to decompression surgery. Especially computed tomography and magnetic resonance (MR) imaging show the actual objective morphological findings, quantitative MR imaging giving additional information concerning the acuteness or chronicity of the disease. Major morphological diagnostic criteria include a spindle like spreading of the rectus muscles without involvement of the tendon, a compression of the optic nerve in the orbital apex (crowded orbital apex syndrome) and the absence of any space occupying intraorbital process. A longer lasting course of the disease may lead to a corresponding impression of the lamina papyracae, the normally parallel configured medial wall of the orbit, similar to a spontaneous decompression.
    Best Practice & Research: Clinical Endocrinology & Metabolism 06/2012; 26(3):259-71. DOI:10.1016/j.beem.2011.11.009 · 4.60 Impact Factor
  • C Best · J Gawehn · F Thömke · W Müller-Forell · M Dieterich ·

    Klinische Neurophysiologie 03/2012; 43(01). DOI:10.1055/s-0032-1301536 · 0.12 Impact Factor
  • H Ridwan · A Kronfeld · J Gawehn · P Stoeter · W Müller-Forell ·

    RöFo - Fortschritte auf dem Gebiet der R 04/2011; 183(S 01). DOI:10.1055/s-0031-1279615 · 1.40 Impact Factor
  • H M Elflein · F Thömke · W Müller-Forell · S Pitz ·
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    ABSTRACT: To describe clinical features and management of 4 patients suffering from unilateral superior oblique palsies due to MRI-documented trochlear nerve schwannomas. Chart reviews of 4 patients seen at the departments of ophthalmogy and neurology at the University of Mainz. All four patients were male, aged 36 to 72 years at initial presentation. None suffered from neurofibromatosis. The history of double vision prior presentation was 9 months to 13 years, follow-up time was 9 to 156 months. Two patients didn't receive any intervention: one remained stable over the follow-up time of 9 months. In patient #2, fourth nerve palsy was diagnosed 13 years prior to confirmation of a trochlear schwannoma by high-resolution MRI. In the third patient disturbing diplopia and head tilt were sufficiently corrected by strabismus surgery (combined oblique muscle surgery). The fourth patient had received stereotactic radiotherapy of an 8 mm schwannoma. He remained unchanged in the orthoptic measurements for 3,5 years. None of these patients developed any additional symptoms or signs of further cranial nerve or central nervous system involvement. A trochlear nerve schwannoma is a possible cause of an isolated unilateral superior oblique palsy. MRI is a helpful tool for diagnosis and follow-up. Conservative management seems to be justified as patients can remain unchanged over years.
    Strabismus 09/2010; 18(3):83-6. DOI:10.3109/09273972.2010.502959
  • J Gawehn · G Fischer · E Schwandt · W Müller-Forell ·

    RöFo - Fortschritte auf dem Gebiet der R 03/2010; 182. DOI:10.1055/s-0030-1252809 · 1.40 Impact Factor
  • S Boor · S Welschehold · K Riedel · C Beyer · T Kerz · A Ayyad · A Reuland · W Müller-Forell ·

    RöFo - Fortschritte auf dem Gebiet der R 03/2010; 182. DOI:10.1055/s-0030-1253055 · 1.40 Impact Factor
  • J Gawehn · G Kutschke · G Vucurevic · W Müller-Forell ·

    RöFo - Fortschritte auf dem Gebiet der R 03/2010; 182. DOI:10.1055/s-0030-1252747 · 1.40 Impact Factor
  • Wibke Müller-Forell · Kristin Engelhard ·
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    ABSTRACT: Neuroimaging is essential in the treatment of cerebral nervous system disorders or in patients in the ICU with deterioration of their neurologic function. Leading clinical symptoms are acute neurologic deficits with different stages of hemisymptomatology, primary or progressing loss of consciousness or vigilance deficit, focal or generalized seizures, sometimes combined with an acute respiratory or circulatory insufficiency. The resulting questions can be summarized in those of intracranial space occupying hemorrhage; acute infarction; and signs for reduced cerebral blood flow, cerebrovascular vasospasm, or intracranial mass. Recent evolutions in imaging have contributed to an increase in diagnostic sensitivity and specificity along with reduced side effects. This article illustrates typical and atypical differential diagnoses, with some emphasis on traumatic brain injury.
    Anesthesiology Clinics 10/2007; 25(3):413-39, vii-viii. DOI:10.1016/j.anclin.2007.06.003
  • W Müller-Forell · P Urban ·
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    ABSTRACT: Isolated cortical vein thrombosis is only rarely diagnosed, although it presents with typical signs on imaging, presented in the paper. We report on five patients with this diagnosis, who all presented with focal sensomotoric seizures. Imaging with CT and MRI was the leading method. All patients were treated with oral anticoagulation and showed full recovery.
    Der Radiologe 04/2007; 47(3):255-61. DOI:10.1007/s00117-005-1281-3 · 0.43 Impact Factor
  • M Nedelmann · W Müller-Forell · M Kaps ·

    Aktuelle Neurologie 01/2007; 34. DOI:10.1055/s-2007-987487 · 0.32 Impact Factor
  • W. Müller-Forell · P Urban ·
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    ABSTRACT: Im klinischen Alltag wird die isolierte oberflächliche Venenthrombose (OVT) selten diagnostiziert, obwohl sich typische bildgebende Befunde finden. Wir berichten von 5 Patienten, die alle wegen fokaler sensomotorischer Anfälle zur Aufnahme kamen. Dabei war die bildgebende Diagnostik mit CT und MRT wegweisend. Nach der Diagnosestellung erfolgte eine orale Antikoagulation, die in allen Fällen zu einer kompletten Beschwerdefreiheit führte.
    Der Radiologe 01/2007; 47(3). · 0.43 Impact Factor
  • Peter P Urban · W Müller-Forell ·
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    ABSTRACT: Isolated cortical vein thrombosis is only rarely diagnosed, although it may commonly be overlooked. We report on four patients with this diagnosis who all presented with focal sensorimotor seizures. The diagnosis was made by a typical CT and MRI-pattern, which is described in detail. The prognosis was excellent in all patients and the treatment options are discussed.
    Journal of Neurology 01/2006; 252(12):1476-81. DOI:10.1007/s00415-005-0893-x · 3.38 Impact Factor
  • W Müller-Forell ·
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    ABSTRACT: Part 2 mainly presents intrinsic lesions as the most common brain tumors (astrocytoma of all grades, ependymoma), arising in the region of the visual pathway. A second focus is on vascular pathology, not only infarction, but cavernoma and venous malformation in Sturge-Weber syndrome. The third topic deals with inflammatory processes such as multiple sclerosis or sarcoidosis.
    Der Radiologe 12/2005; 45(11):1043-55. DOI:10.1007/s00117-005-1278-y · 0.43 Impact Factor
  • W Müller-Forell ·
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    ABSTRACT: The clinical symptoms of lesions affecting the intracranial visual pathway vary as widely as their aetiology. The anatomy, the basics of neuro-ophthalmology and MRI protocols are touched on in the first part of this serial paper; in addition the most important pathological entities affecting the sellar region are presented. The focus is on the differentiation between extrinsic and intrinsic lesions, but in addition to this vascular lesions are presented with reference to illustrative cases.
    Der Radiologe 11/2005; 45(10):941-53; quiz 954-5. · 0.43 Impact Factor
  • Source
    B K Nguyen-Huu · A Thümler · B Weisner · K Wernicke · W Müller-Forell · H Schmidt · K J Werhahn ·
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    ABSTRACT: Listeriosis is a bacterial infection with Listeria monocytogenes mostly affecting immunocompromised patients. In every fourth case, the CNS is involved, usually as meningoencephalitis. This case report of an immunocompetent woman represents the first one of neurolisteriosis initially presenting as cervical myelitis and progressing to supratentorial areas of the brain. Diagnosis was based on universal polymerase chain reaction from a cortical brain biopsy, followed by sequencing of the amplified rDNA gene. Under antibiotic treatment with gentamycin and ampicillin, the patient slowly recovered and has been improving ever since.
    Der Nervenarzt 11/2005; 76(10):1255-8. · 0.79 Impact Factor
  • W. Müller-Forell ·
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    ABSTRACT: Die klinische Symptomatik der Läsionen des intrakraniellen Abschnitts der Sehbahn ist ebenso vielfältig wie ihre möglichen Ursachen. Im ersten Teil werden die Anatomie in Kurzform, die neuroophthalmologischen Grundlagen, die Untersuchungsprotokolle mittels MRT sowie die wichtigsten Erkrankungen der Sellaregion und ihre Differenzialdiagnosen dargestellt. Dabei wird ein Hauptaugenmerk auf die Einteilung der Tumorerkrankungen in Bezug zum Ausgangspunkt ihres Wachstums (extrinsisch/intrinsisch) gelegt, aber auch wichtige Gefäßerkrankungen werden anhand von beispielhaften Fällen dargestellt.
    Der Radiologe 10/2005; 45(10):941-955. DOI:10.1007/s00117-005-1276-0 · 0.43 Impact Factor

Publication Stats

663 Citations
113.54 Total Impact Points


  • 2013
    • Universitätsklinikum Freiburg
      • Institute of Neuropathology
      Freiburg an der Elbe, Lower Saxony, Germany
  • 1989-2012
    • Johannes Gutenberg-Universität Mainz
      • • Department of Neurobiology
      • • Institute of Neuroradiology
      • • Klinik und Poliklinik für Neurologie
      • • III. Department of Medicine
      • • Department of Neurosurgery
      Mayence, Rheinland-Pfalz, Germany