J C Sahuquillo

Publications (5)12.1 Total impact

• Source

  Available from: Luciano Lopez

  Article: Glucose control and outcome in patients with stable diabetes and previous coronary, cerebrovascular or peripheral artery disease. Findings from the FRENA Registry.

  M Camafort, L R Alvarez-Rodríguez, J F S Muñoz-Torrero, J C Sahuquillo, L López-Jiménez, R Coll, M Monreal
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  ABSTRACT: The aim of this study was to address the controversy over the influence of intensive glucose control on the risk for cardiovascular events in patients with Type 2 diabetes. FRENA is an ongoing registry of stable outpatients with symptomatic coronary artery disease, cerebrovascular disease or peripheral artery disease. We compared the incidence of subsequent ischaemic events (myocardial infarction, stroke or critical limb ischaemia) in patients with Type 2 diabetes and mean HbA(1c) levels < 7.0% (< 53 mmol/mol) vs. those with HbA(1c) levels > 7.0% (> 53 mmol/mol). Of 974 patients with Type 2 diabetes, 480 (49%) had mean HbA(1c) levels < 7% (< 53 mmol/mol). Over a mean follow-up of 14 months, 126 patients (13%) had subsequent ischaemic events: myocardial infarction (43), stroke (29) and critical limb ischaemia (64). The incidence of subsequent ischaemic events was significantly lower in patients with mean HbA(1c) levels < 7.0% (< 53 mmol/mol) than in those with HbA(1c) levels > 7.0% (> 53 mmol/mol) (8.6 vs. 14 per 100 patient-years; rate ratio 0.6; 95% CI 0.4-0.9). These differences persisted after adjusting for potential confounders. However, this better outcome was only found in patients presenting with coronary artery disease (rate ratio 0.4; 95% CI 0.2-0.8), not in those with cerebrovascular disease (rate ratio 0.9; 95% CI 0.4-2.0) or peripheral artery disease (rate ratio 0.8; 95% CI 0.5-1.3). Patients with mean HbA(1c) levels < 7.0% (< 53 mmol/mol) also had a lower mortality (rate ratio 0.6; 95% CI 0.3-0.99). In secondary prevention, patients with diabetes and HbA(1c) levels < 7.0% (< 53 mmol/mol) had a lower incidence of subsequent ischaemic events and a lower mortality than those with HbA(1c) levels > 7.0% (> 53 mmol/mol). These differences appeared only in patients with coronary artery disease.
  Diabetic Medicine 01/2011; 28(1):73-80. · 2.90 Impact Factor
• Article: [Analysis of internal notices to the emergency team of the medical area at a general hospital].

  P Tudela, M J Rego, J Tor, O Estrada, J M Mòdol, J C Sahuquillo
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  ABSTRACT: To study the frequency and characteristics of the hospitalized patients medical emergencies. We have collected daily the notice to the emergency room from patients hospitalized and we have analyzed the clinical and epidemiological characteristics. Three hundred forty-one notices were recorded. The daily mean was higher on holidays. There were mostly medical problems (78%). Complementary explorations were performed in the 44% of the patients, and in the 77% the treatment was changed. The in-patient emergencies account for an important charge of work for the emergency team and involve important diagnosis and therapeutic decisions.
  Medicina Clínica 06/2000; 114(19):730-1. · 1.38 Impact Factor
• Article: [The new staff members].

  J C Sahuquillo
  Medicina Clínica 06/1998; 110(19):759. · 1.38 Impact Factor
• Article: Occult cancer in patients with venous thromboembolism: which patients, which cancers.

  M Monreal, J Fernandez-Llamazares, J Perandreu, A Urrutia, J C Sahuquillo, E Contel
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  ABSTRACT: We have previously demonstrated that patients with idiopathic venous thromboembolism (VTE) have a higher frequency of underlying cancer. Now we present a retrospective analysis of our 5-year experience with a series of 674 consecutive otherwise healthy patients, and a more restricted battery of diagnostic tests. Occult cancer was found in 15 patients during admission. The diagnostic tools which led to suspect occult cancer were: abdominal CT-scan (4 patients); high carcinoembryonic levels (2 patients); and high prostate-specific antigen levels (9 patients). Eight further patients were diagnosed of cancer after discharge. Cancer was more commonly found in patients with idiopathic VTE: 13/105 patients (12%) versus 10/569 patients (2%); p <0.01; O.R.: 7.9 (95% CI: 3.14-20.09). During the same period of time we diagnosed VTE in 147 patients with previously known cancer. When overall considered, VTE was the first sign of malignancy in most patients with prostatic and pancreatic carcinoma. On the contrary, most patients with breast, lung, uterine and brain cancers developed VTE as a terminal event of the disease. At variance with VTE patients and previously known cancer, most patients with occult malignancy were at an early stage. Further studies are needed to confirm whether patients with idiopathic VTE could benefit from screening for occult cancer. Meanwhile, our findings may serve as guidelines for physicians in this field.
  Thrombosis and Haemostasis 11/1997; 78(5):1316-8. · 5.04 Impact Factor
• Article: [Fever, adenopathies, hepatosplenomegaly and cutaneous lesions in a 31-year-old woman with human immunodeficiency virus infection].

  J C Sahuquillo, I Moysset
  Medicina Clínica 03/1995; 104(5):188-95. · 1.38 Impact Factor