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ABSTRACT: High malaria burden has led to the increase use of insecticides in the tropics and subtropics. This study thus aimed at assessing the haematological effects and associated haemostatic alteration of pyrethroid insecticide exposure using experimental animal model. Rats of comparable ages and weights were randomized into four groups (A-D). Rats in groups B, C and D were exposed to pyrethroid insecticide by inhalation for 1, 2 and 3 min daily respectively for three weeks. Rats in group A (control) were not exposed. Haematological and haemostatic variables were comparable in all groups (< 0.05). Results from the study show that minimal exposure to pyrethroids is safe.Pakistan Journal of Biological Sciences 11/2011; 14(22):1024-7.