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ABSTRACT: A system where model parts can be easily exchanged and modified is of great advantage, especially in a combination of models such as an electrophysiological cell model and a mechanical model to a more complex left ventricular (LV) motion model. The use of a distributed simulation environment is straightforward because each simulation model is calculated by an existing user-friendly simulator. However, the weak coupling calculation usually used in a distributed environment reduces the accuracy of the simulation and results in an unstable simulation of the LV motion. To overcome this problem, we have developed a strong coupling simulation system for the distributed simulation environment. Simulation results for a myocardial tissue and a simple LV shape model are presented to elucidate the effectiveness of our system
Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the; 02/2006