[Show abstract][Hide abstract] ABSTRACT: End stage renal disease (ESRD) represents a clinical condition in which there is an irreversible loss of endogenous renal function. Both structural and functional abnormalities of the kidney are associated with increased morbidity, mortality. Bardet-Biedel syndrome (BBS) is one of the rare genetic disorders with prevalence of 1 in 1, 40,000-1 in 1,60,000 worldwide. ESRD in BBS patients is the final stage of the disease, increasing mortality in youth.
Indian Journal of Clinical Biochemistry 04/2011; 26(2):214-6. DOI:10.1007/s12291-011-0116-4