Publications (2)1.32 Total impact
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Article: A study on in vitro and in vivo bioactivity of nano hydroxyapatite/polymer biocomposite
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ABSTRACT: When bioactive materials are implanted in vivo, a bone-like apatite layer can be found on their surfaces, which is critical to the establishment of bone-bonding between materials and living tissues. In this study, bone-like apatite formation in vitro and in vivo on surface of nano apatite/polyamide (n-HA/PA66) composite was investigated, and the interface between the implanted composite and surrounding bone tissue of rabbit were also examined. The results revealed that in both simulated body fluids (SBF) and dorsal muscles of rabbit, bone-like apatite could form on the biocomposite surface. When the samples were implanted in cortical bone, they combined directly with the natural bone without fibrous tissue in-between. The results showed that the n-HA/PA66 biocomposite had excellent bioactivity, which might be a good candidate for bone defect replacement.Chinese Science Bulletin 04/2012; 52(2):267-271. · 1.32 Impact Factor -
Article: A study on biocomposite of nano apatite/poly (1,4-phenylene-sulfide)–poly (2,4-phenylene sulfide acid)
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ABSTRACT: A new type of biocomposite of nano aptite (NAP)/poly(1,4-phenylene sulfide)–poly (2,4-phenylene sulfide acid) (PPS–PPSA) copolymer (NAP/PPS–PPSA) was prepared by polycondensation in 1-methyl-2-pyrrolidone (NMP). The NAP particles with a size of about 40–60 nm in diameter and 60–80 nm in length uniformly distributed in the composite. The presence of 2,4-phenylene sulfide acid in copolymer increased the copolymer affinity to NAP. Duo to some strong combinations of calcium ion (Ca2+), carboxyl (–COO−) and phosphate radicals ion () in the composite, interfacial chemical binding exists between copolymer and NAP. The NAP/PPS–PPSA biocomposite not only had good homogeneity but also had high NAP content of 60%, which was a potential bioactive material to be used as load-bearing implants or fixation in bone repair.Composites Part B: Engineering.
