ABSTRACT: In this chapter, we discuss the process of supramolecular engineering in the self-assembly of guanine derivatives on conductive solid substrate, i.e. highly oriented pyrolitic graphite (HOPG), as investigated by scanning tunneling microscopy (STM). In the first section, we focus on the exploration of systems engineered to form assemblies through the formation of hydrogen-bonds and van der Waals (vdW) interactions. We then present recent examples in 2D crystal engineering using alkylated guanosine derivatives. Further on, we give a perspective into the strategies employed alkyl chain interdigitation as the main building strategy for nanopatterning surfaces with guanine molecules. In the second section we describe systems based on metallo–ligand interactions as well as protonation as a way to trigger dynamic processes in guanine-based dynamers. In the final section discuss the use of guanosine derivatives as scaffolds for the controlled positioning of electrically/optically active groups in 2D.
01/2013: pages 40-47; , ISBN: 978-1-84973-695-4